ID A0A0V0R4S5_PSEPJ Unreviewed; 1528 AA.
AC A0A0V0R4S5;
DT 16-MAR-2016, integrated into UniProtKB/TrEMBL.
DT 16-MAR-2016, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE SubName: Full=Cyclic nucleotide-binding protein {ECO:0000313|EMBL:KRX09492.1};
GN ORFNames=PPERSA_12235 {ECO:0000313|EMBL:KRX09492.1};
OS Pseudocohnilembus persalinus (Ciliate).
OC Eukaryota; Sar; Alveolata; Ciliophora; Intramacronucleata;
OC Oligohymenophorea; Scuticociliatia; Philasterida; Pseudocohnilembidae;
OC Pseudocohnilembus.
OX NCBI_TaxID=266149 {ECO:0000313|EMBL:KRX09492.1, ECO:0000313|Proteomes:UP000054937};
RN [1] {ECO:0000313|EMBL:KRX09492.1, ECO:0000313|Proteomes:UP000054937}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=36N120E {ECO:0000313|EMBL:KRX09492.1};
RX PubMed=26486372; DOI=10.1038/srep15470;
RA Xiong J., Wang G., Cheng J., Tian M., Pan X., Warren A., Jiang C., Yuan D.,
RA Miao W.;
RT "Genome of the facultative scuticociliatosis pathogen Pseudocohnilembus
RT persalinus provides insight into its virulence through horizontal gene
RT transfer.";
RL Sci. Rep. 5:15470-15470(2015).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KRX09492.1}.
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DR EMBL; LDAU01000048; KRX09492.1; -; Genomic_DNA.
DR EnsemblProtists; KRX09492; KRX09492; PPERSA_12235.
DR InParanoid; A0A0V0R4S5; -.
DR OrthoDB; 204138at2759; -.
DR Proteomes; UP000054937; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR CDD; cd00038; CAP_ED; 1.
DR Gene3D; 1.10.287.70; -; 1.
DR Gene3D; 2.60.120.10; Jelly Rolls; 1.
DR InterPro; IPR000595; cNMP-bd_dom.
DR InterPro; IPR018490; cNMP-bd_dom_sf.
DR InterPro; IPR013099; K_chnl_dom.
DR InterPro; IPR014710; RmlC-like_jellyroll.
DR PANTHER; PTHR45689; I[[H]] CHANNEL, ISOFORM E; 1.
DR PANTHER; PTHR45689:SF5; I[[H]] CHANNEL, ISOFORM E; 1.
DR Pfam; PF00027; cNMP_binding; 1.
DR Pfam; PF07885; Ion_trans_2; 1.
DR SMART; SM00100; cNMP; 1.
DR SUPFAM; SSF51206; cAMP-binding domain-like; 1.
DR SUPFAM; SSF81324; Voltage-gated potassium channels; 1.
DR PROSITE; PS50042; CNMP_BINDING_3; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Magnesium {ECO:0000256|ARBA:ARBA00022842};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000054937};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 158..176
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 188..207
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 295..404
FT /note="Cyclic nucleotide-binding"
FT /evidence="ECO:0000259|PROSITE:PS50042"
FT REGION 1..28
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 847..901
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 921..988
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1026..1139
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1186..1211
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1501..1528
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 1368..1402
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 881..901
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1026..1062
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1090..1139
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1528 AA; 179383 MW; A7141254AC33F2DB CRC64;
MNVQKQNFIK QNEKEKNNLQ QKQEQQNQFQ PHNLMKKFQS FNNSQILSNY QAKKIQKIFE
IMKIRQKGIK TLILTSQKYR YRTFTDAILN FFNDKSFYYS NKSPKHKENE KWIYACDKLL
QKLPVLQPSG WFKISIENGT HNWTDLVPNQ TPESLKGFIL YNYAFYYATA TMLTVGYGDI
YPMNQTEITI AIIFMMFACI IQSFFIGKIQ SIMNNLQQDN IEKNEIISQL NRYIKNTPIS
KSLKQSIIEY IQYYFKYNVE DQINFESKLR SMLNQPLRKS LMQESYKNIL TSPIFANNFS
PTVLQKLIIF IEEVKLSPDQ LVLQKNQHDN SLIFVENGKL EIFIEKDAKL ENYIEETNTL
KTIQKGESVG AFEFFTAAAN RYSVRSRGYG AILQIKRSDF VNLIKDYPED YEKFIYLQDS
VIYSQNYLGI ANKCLACHSI WHFSHDCPYI SLKVNKQKLI HQCLKFVPQI RKSYIRNAKN
FKAKKNSLLN MIFIQDRAQD LQLNNSQLIE NLSYIIDEDD FCTSFYNSSV NQSYSYDLNS
TDFQNEDEIV DNNKINKKNK SYSPQIQFSD IIEENEKSQQ DYNSFNLKSE QNENTLNPNQ
NLNSKSKGAF QTENNIIKVE QLFSIDKSQN LNQNKNRAFS SFNVNTKPQN TKKFSLVLQQ
FLNKGNKENN LINPKKITSC KQIQSIQQRL LDPGNPLLRQ RKNEFTQPVN LQISYQNSIN
SVRTLSNSNN NLSSSHLQKK KQRKFLFEQE ETKNLFYDQK KTSLDSKIPS AKQNNLLNQI
YLQHTLSQNT NQIQDQKQKQ IQIQNEKKQK NQNFQPKMQK IKSKQYMSNN ILVYNENNLQ
AQIKEYSDPL SSLSSLGDTE SDSPRRKKLK KPKKNQEQKE NQFGNENQNQ KQDKQNNQQK
NSQIIKIQEN EQNIEQKLQQ DVENRSFSSS SFSSSQPSSS SQQSSIKNQQ NSSNSSSELS
VITSNSSSPP KQHIQKNLNI PRTSKGTSSI SELREIIFQQ KISQKTEKNK AQKSQNNHEI
QSENIQFSKK EQEQQQVQNF STDQNLIKRK ISKKYSQQPQ NQNKKNKEKR QSTPMLTSDQ
VKKLSHIKIN IKNNKLNNNN QDNNFQNNYQ DNNQQINQNI NDNQNRNQNI NDNQNRNQNV
NQNSNIFINL NENNNNTTIT GTKTNKCLNK KQSDNNSNKN HLNIKQQKIS QQQQQLSQFG
NRKSKDLSQL SKGAVNTSGS FILQQNSQIQ QNSQFKNSQE ITVDFSQTQK YSQFKQTDQN
KRKLKKLRSE EFSSQYLKQL SGNFQNIQYI NQKKENKNLI NPNINNNNTS PIQNFPQLIA
NNSHNEIQNQ NNQQQFQLFN QFIQFQKFQQ FQNQQQQQQQ QNQQQQFYSQ INSQAEKQQQ
QLQQVQEQAE KVEQQKMNQK QQKLLDIDFS CALDLDTKKE FKIYYPNFNY TTLLFKFSEF
QKPIIEETFK RRKQRYKTKI LNTMAKSRTF HKKRMGLGMS MSKQGNDFMF DSFANKINSG
SQNQLKNSLG TNQTLNLKNS NQNNNNNQ
//
