ID A0A0V0RND0_9BILA Unreviewed; 712 AA.
AC A0A0V0RND0;
DT 16-MAR-2016, integrated into UniProtKB/TrEMBL.
DT 16-MAR-2016, sequence version 1.
DT 27-MAR-2024, entry version 36.
DE RecName: Full=Homeobox protein engrailed-like {ECO:0000256|RuleBase:RU510713};
DE Flags: Fragment;
GN Name=eng1a {ECO:0000313|EMBL:KRX15977.1};
GN ORFNames=T07_10035 {ECO:0000313|EMBL:KRX15977.1};
OS Trichinella nelsoni.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Enoplea; Dorylaimia;
OC Trichinellida; Trichinellidae; Trichinella.
OX NCBI_TaxID=6336 {ECO:0000313|EMBL:KRX15977.1, ECO:0000313|Proteomes:UP000054630};
RN [1] {ECO:0000313|EMBL:KRX15977.1, ECO:0000313|Proteomes:UP000054630}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ISS37 {ECO:0000313|EMBL:KRX15977.1};
RA Korhonen P.K., Edoardo P., Giuseppe L.R., Gasser R.B.;
RT "Evolution of Trichinella species and genotypes.";
RL Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123,
CC ECO:0000256|PROSITE-ProRule:PRU00108, ECO:0000256|RuleBase:RU000682}.
CC -!- SIMILARITY: Belongs to the Engrailed homeobox family.
CC {ECO:0000256|RuleBase:RU510713}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KRX15977.1}.
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DR EMBL; JYDL01000118; KRX15977.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0V0RND0; -.
DR STRING; 6336.A0A0V0RND0; -.
DR Proteomes; UP000054630; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0140664; F:ATP-dependent DNA damage sensor activity; IEA:InterPro.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0000981; F:DNA-binding transcription factor activity, RNA polymerase II-specific; IEA:InterPro.
DR GO; GO:0006281; P:DNA repair; IEA:InterPro.
DR GO; GO:0007399; P:nervous system development; IEA:UniProt.
DR CDD; cd00086; homeodomain; 1.
DR Gene3D; 1.10.10.60; Homeodomain-like; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR013632; DNA_recomb/repair_Rad51_C.
DR InterPro; IPR019549; Homeobox-engrailed_C-terminal.
DR InterPro; IPR009057; Homeobox-like_sf.
DR InterPro; IPR017970; Homeobox_CS.
DR InterPro; IPR001356; Homeobox_dom.
DR InterPro; IPR000747; Homeobox_engrailed.
DR InterPro; IPR020479; Homeobox_metazoa.
DR InterPro; IPR019737; Homoebox-engrailed_CS.
DR InterPro; IPR000047; HTH_motif.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR020588; RecA_ATP-bd.
DR PANTHER; PTHR24341; HOMEOBOX PROTEIN ENGRAILED; 1.
DR PANTHER; PTHR24341:SF6; HOMEOBOX PROTEIN INVECTED-RELATED; 1.
DR Pfam; PF10525; Engrail_1_C_sig; 1.
DR Pfam; PF00046; Homeodomain; 1.
DR Pfam; PF08423; Rad51; 1.
DR PRINTS; PR00026; ENGRAILED.
DR PRINTS; PR00024; HOMEOBOX.
DR PRINTS; PR00031; HTHREPRESSR.
DR SMART; SM00382; AAA; 1.
DR SMART; SM00389; HOX; 1.
DR SUPFAM; SSF46689; Homeodomain-like; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS00033; ENGRAILED; 1.
DR PROSITE; PS00027; HOMEOBOX_1; 1.
DR PROSITE; PS50071; HOMEOBOX_2; 1.
DR PROSITE; PS50162; RECA_2; 1.
PE 3: Inferred from homology;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|PROSITE-
KW ProRule:PRU00108};
KW Homeobox {ECO:0000256|ARBA:ARBA00023155, ECO:0000256|PROSITE-
KW ProRule:PRU00108};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|PROSITE-
KW ProRule:PRU00108}; Reference proteome {ECO:0000313|Proteomes:UP000054630}.
FT DOMAIN 38..209
FT /note="RecA family profile 1"
FT /evidence="ECO:0000259|PROSITE:PS50162"
FT DOMAIN 609..669
FT /note="Homeobox"
FT /evidence="ECO:0000259|PROSITE:PS50071"
FT DNA_BIND 611..670
FT /note="Homeobox"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00108"
FT REGION 470..498
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 593..616
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 691..712
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 595..616
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:KRX15977.1"
SQ SEQUENCE 712 AA; 79053 MW; 2EE4E60D5CF6222F CRC64;
LENMNMRGDV SGYRCACNPD CTLKMFSGID LYSDMYRNIC AFSTGYEAMD GMLKGGIYSS
ELTELVGPVG SGKTQFCLTF VANLVKQTGG RVLFIDTTGG FSGVRLAEIL LSRTSSSEIQ
IIHELLSKVV VEFAVSHDDL NRILEGVEQN AEGILTKLKV IVVDHVGTIL SPTVFGEREM
GIQKTMKTCL RLRNLAKDFN LAVLVVNSAV ELDDGEIRPM LGQWWAAMPD TRLLFRTLDF
NFYSVTLIKS CKLSIGEAVS FSCGLEGVKC PESALYEKQC ARTFIKARKE AASGQARAAA
KMTRRTKKML IPLQIGQNCT LRVPDVDRGP ADPKNFLVVV MAECEGLYTV GCREGKLASK
FTAADLQVIS ENILSIDEVP DTEIPLRTAV TKATGGQGYV KCMCLSGCSC GRCSCSRKRV
LCNSRCHPGK ILFSEGDKAN SPIYQSRGAD QSLKGAYLAM TLCVKVKPQT RQPSLGSDGE
HSDSESASPS PSSAKETNAN ELEQLYSRAE LKFSVENILK PDFGLHSRSE MINKNLKEMK
TSMNLNTKRP STSSGNGQIS KSLSEMTGCE SQMKNVPQVL WPAWVYCTRY SDRPSSGPRN
RRIRNKAKAD EKRPRTAFTT QQLERLRFEF QENRYLTEKR RQELASELGL NESQIKIWFQ
NKRAKIKKQN RCNNLLAIQL MAQGLYNHTT STRLTSSKNN DISDEEEEEL SP
//
