ID A0A0V0RSU3_9BILA Unreviewed; 1490 AA.
AC A0A0V0RSU3;
DT 16-MAR-2016, integrated into UniProtKB/TrEMBL.
DT 16-MAR-2016, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE SubName: Full=Antigen-like protein {ECO:0000313|EMBL:KRX17550.1};
GN Name=CD109 {ECO:0000313|EMBL:KRX17550.1};
GN ORFNames=T07_6853 {ECO:0000313|EMBL:KRX17550.1};
OS Trichinella nelsoni.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Enoplea; Dorylaimia;
OC Trichinellida; Trichinellidae; Trichinella.
OX NCBI_TaxID=6336 {ECO:0000313|EMBL:KRX17550.1, ECO:0000313|Proteomes:UP000054630};
RN [1] {ECO:0000313|EMBL:KRX17550.1, ECO:0000313|Proteomes:UP000054630}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ISS37 {ECO:0000313|EMBL:KRX17550.1};
RA Korhonen P.K., Edoardo P., Giuseppe L.R., Gasser R.B.;
RT "Evolution of Trichinella species and genotypes.";
RL Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KRX17550.1}.
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DR EMBL; JYDL01000086; KRX17550.1; -; Genomic_DNA.
DR Proteomes; UP000054630; Unassembled WGS sequence.
DR GO; GO:0005615; C:extracellular space; IEA:InterPro.
DR GO; GO:0004866; F:endopeptidase inhibitor activity; IEA:InterPro.
DR CDD; cd02897; A2M_2; 1.
DR Gene3D; 1.50.10.20; -; 1.
DR Gene3D; 2.20.130.20; -; 1.
DR Gene3D; 2.60.120.1540; -; 1.
DR Gene3D; 2.60.40.1930; -; 2.
DR Gene3D; 2.60.40.1940; -; 1.
DR Gene3D; 2.60.40.2950; -; 1.
DR Gene3D; 6.20.50.160; -; 1.
DR Gene3D; 2.60.40.690; Alpha-macroglobulin, receptor-binding domain; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 2.
DR InterPro; IPR009048; A-macroglobulin_rcpt-bd.
DR InterPro; IPR036595; A-macroglobulin_rcpt-bd_sf.
DR InterPro; IPR011625; A2M_N_BRD.
DR InterPro; IPR041813; A2M_TED.
DR InterPro; IPR047565; Alpha-macroglob_thiol-ester_cl.
DR InterPro; IPR011626; Alpha-macroglobulin_TED.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR001599; Macroglobln_a2.
DR InterPro; IPR019742; MacrogloblnA2_CS.
DR InterPro; IPR002890; MG2.
DR InterPro; IPR041555; MG3.
DR InterPro; IPR008930; Terpenoid_cyclase/PrenylTrfase.
DR PANTHER; PTHR11412:SF179; LD23292P; 1.
DR PANTHER; PTHR11412; MACROGLOBULIN / COMPLEMENT; 1.
DR Pfam; PF00207; A2M; 1.
DR Pfam; PF07703; A2M_BRD; 1.
DR Pfam; PF07677; A2M_recep; 1.
DR Pfam; PF01835; MG2; 1.
DR Pfam; PF17791; MG3; 1.
DR Pfam; PF07678; TED_complement; 1.
DR SMART; SM01360; A2M; 1.
DR SMART; SM01359; A2M_N_2; 1.
DR SMART; SM01361; A2M_recep; 1.
DR SMART; SM01419; Thiol-ester_cl; 1.
DR SUPFAM; SSF49410; Alpha-macroglobulin receptor domain; 1.
DR SUPFAM; SSF48239; Terpenoid cyclases/Protein prenyltransferases; 1.
DR PROSITE; PS00477; ALPHA_2_MACROGLOBULIN; 1.
PE 4: Predicted;
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Reference proteome {ECO:0000313|Proteomes:UP000054630};
KW Signal {ECO:0000256|ARBA:ARBA00022729};
KW Thioester bond {ECO:0000256|ARBA:ARBA00022966}.
FT DOMAIN 465..600
FT /note="Alpha-2-macroglobulin bait region"
FT /evidence="ECO:0000259|SMART:SM01359"
FT DOMAIN 725..816
FT /note="Alpha-2-macroglobulin"
FT /evidence="ECO:0000259|SMART:SM01360"
FT DOMAIN 1341..1430
FT /note="Alpha-macroglobulin receptor-binding"
FT /evidence="ECO:0000259|SMART:SM01361"
SQ SEQUENCE 1490 AA; 166617 MW; EEF148377E91C580 CRC64;
MLYLFVRLFT STGSYVILAP RLVRPNLPYV ISVNLLESRQ PVVIRARILD SQNQSIAHTW
GQDLQSGKLT EVRIEKIPSH LPPETVYTLF VQGETVSGRV LFQKSAKLEF VHKSLSIFIQ
TDKGIYKPGS DVHIRVVVVE PNMKPYKGAA NITIMDPSGN MIVQHLDVPI VAGICGMNDS
LMLRLTSAPA LGQWQITVDV DGETQFQKFT VEKYVLPKFE VKVTPPSVST ISDDITVFVS
AKYTNGRGVE GNVTIKAEYP WPYYGSEELQ DVVKKTTLDH VGEAAFQFAN EELRQKKLIN
EYGYNQIKFT AIVTERLTGE TRNGSSTVTV HQHPIKVELI RSSDFFKAGI NYTFRVAVKT
QDDKPFISDS HSDIFLSVDF IIRQLHHHND NTTTADFANF TIFDPKREKY NQVVKLESDG
TQMVTISTPF NASSMRIEAH YGSEESNVYT FDYIDASHSP SNNFLQIISK QDEISDQKFL
TFDVIASTAV KEVYAFVIAR ATIVWSGQVL FENFKATLQI ESSKEMIPKA RLLAYALIPD
TKEILVDALD FKFSNGFSDQ INLSITPDTV EPNENVTFSI NAPPSSYVGL LVVDQSVLLM
QSPNDITLEA VENEILSYEL FSYGYHGLTQ VAIDRRKKRT ICYRCGVFGA GSKDAYSIFQ
NSGIIVITDA FLYQQLNSPF LFRVAAPALA SLSADVDNDL MVGSVMTKSG STSLNVRLRS
HFPETWIWAD LFANEHGLAV YNAVAPDTIT SWIASAFSLS EQYGLNALSD AKKVTVFRPF
FIRLQLPYSV KRGEAIALQV LIFNYLDKDE KVNVILDYHK DSGFEFIVKK SVSSMIKKSV
EVKPENSKTV TVKHESSSAA YFLIRPTKVG TLKLSVKAFA QSAADAIQVP LLVEAEGYPV
SYTRSFAIDM KERNTFKQSF QLDHPEDMID DSMKIEVSVI GDIMAPVIKN LDSLIHMPDG
CGEQNMIHFV PNIAVMQYLI STNRLESNLK QTLLRYMEAG YQRELTYRRN DDSYSAFGNA
DQQGSTWLTA FVVRSFSEAK SFIFIDEEKL KLSAAFLANQ QKENGMFEEN GQVLHSGLQG
GSGQGGVPLT AYVYIALLKT GTNNLEALNY LEQSLDYISN NTYAVSITAY ALHLANSSKK
DSAFYLLEKL SSSKDGQKFW AAESSGESNN GKNMSWYEKP RPADVESTAY ALLVHVLRGE
ASNAFPIVRW LTMQQDAFGG FSSSQDTVVG LQALAAFAEA TYSDNVEMDV TVKNGNEEAA
FAISSKNSLV LQTYEIRNFV EKQIDIFATG RGLAFAQIKW RYNVKSLDNN RPFLCETDVS
QQAYTALTVS FCCKYMFEGT SNMAIMELTA PSGFVIDVQQ LNGLTDTNQL QMVETKKQDT
QANIYFDSIG ISPICFNVSS KLAYQVADQK PAIVRLYDYY EPQNRIEFEY KVKKEVSIED
ACGDSCYAEI SSAALTEQPA SKGTMPNCCS IIQTLPVLIY LFYYSVLRFH
//
