ID A0A0V0S308_9BILA Unreviewed; 800 AA.
AC A0A0V0S308;
DT 16-MAR-2016, integrated into UniProtKB/TrEMBL.
DT 16-MAR-2016, sequence version 1.
DT 27-MAR-2024, entry version 29.
DE SubName: Full=Rho GTPase-activating protein 10 {ECO:0000313|EMBL:KRX21147.1};
GN Name=arhgap26 {ECO:0000313|EMBL:KRX21147.1};
GN ORFNames=T07_416 {ECO:0000313|EMBL:KRX21147.1};
OS Trichinella nelsoni.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Enoplea; Dorylaimia;
OC Trichinellida; Trichinellidae; Trichinella.
OX NCBI_TaxID=6336 {ECO:0000313|EMBL:KRX21147.1, ECO:0000313|Proteomes:UP000054630};
RN [1] {ECO:0000313|EMBL:KRX21147.1, ECO:0000313|Proteomes:UP000054630}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ISS37 {ECO:0000313|EMBL:KRX21147.1};
RA Korhonen P.K., Edoardo P., Giuseppe L.R., Gasser R.B.;
RT "Evolution of Trichinella species and genotypes.";
RL Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KRX21147.1}.
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DR EMBL; JYDL01000042; KRX21147.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0V0S308; -.
DR STRING; 6336.A0A0V0S308; -.
DR Proteomes; UP000054630; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:InterPro.
DR GO; GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.
DR GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR CDD; cd01249; BAR-PH_GRAF_family; 1.
DR Gene3D; 1.20.1270.60; Arfaptin homology (AH) domain/BAR domain; 1.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR Gene3D; 1.10.555.10; Rho GTPase activation protein; 1.
DR Gene3D; 2.30.30.40; SH3 Domains; 1.
DR InterPro; IPR027267; AH/BAR_dom_sf.
DR InterPro; IPR004148; BAR_dom.
DR InterPro; IPR047234; GRAF_fam.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR001849; PH_domain.
DR InterPro; IPR047225; PH_GRAF.
DR InterPro; IPR008936; Rho_GTPase_activation_prot.
DR InterPro; IPR000198; RhoGAP_dom.
DR InterPro; IPR036028; SH3-like_dom_sf.
DR InterPro; IPR001452; SH3_domain.
DR PANTHER; PTHR12552; OLIGOPHRENIN 1; 1.
DR PANTHER; PTHR12552:SF1; RHO GTPASE-ACTIVATING PROTEIN GRAF; 1.
DR Pfam; PF16746; BAR_3; 1.
DR Pfam; PF00169; PH; 1.
DR Pfam; PF00620; RhoGAP; 1.
DR Pfam; PF14604; SH3_9; 1.
DR SMART; SM00233; PH; 1.
DR SMART; SM00324; RhoGAP; 1.
DR SMART; SM00326; SH3; 1.
DR SUPFAM; SSF103657; BAR/IMD domain-like; 1.
DR SUPFAM; SSF48350; GTPase activation domain, GAP; 1.
DR SUPFAM; SSF50729; PH domain-like; 1.
DR SUPFAM; SSF50044; SH3-domain; 1.
DR PROSITE; PS50003; PH_DOMAIN; 1.
DR PROSITE; PS50238; RHOGAP; 1.
DR PROSITE; PS50002; SH3; 1.
PE 4: Predicted;
KW GTPase activation {ECO:0000256|ARBA:ARBA00022468};
KW Reference proteome {ECO:0000313|Proteomes:UP000054630};
KW SH3 domain {ECO:0000256|ARBA:ARBA00022443, ECO:0000256|PROSITE-
KW ProRule:PRU00192}.
FT DOMAIN 270..377
FT /note="PH"
FT /evidence="ECO:0000259|PROSITE:PS50003"
FT DOMAIN 391..584
FT /note="Rho-GAP"
FT /evidence="ECO:0000259|PROSITE:PS50238"
FT DOMAIN 741..800
FT /note="SH3"
FT /evidence="ECO:0000259|PROSITE:PS50002"
FT REGION 646..667
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 715..738
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 646..666
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 800 AA; 91496 MW; 78D6DCB6DA770258 CRC64;
MVLKPLEFAD CVTDSPWFRA NLREHELALE RSYKSIKLLE SQSKELISAG QKLQTAQRNF
AKTLQELKLE TIGTTETEDE RIIANSLKEY SKLILQLEDQ RSHILQETEK NFIGPFRKFR
IECIGNAIQH ERKKYEKSSY KFYQTLEKHL HLSTNKRNDF KEADTALEAE QRQFYRASLD
YVCVLQSVQE RMKFEFVENL SSFLYSLLTF YHVGHVIHED FKPYLDHVKY RVQKAKESHY
ATERETEEFR KKMLRLNSMS HPMEMCAGRV AIKQGYLYLC EKKNLVTSWT KYYCVYQKET
RMFAIVPVTQ TLIKDIKEAF CQSISFKLKS CIRRASDTID KRFCFDIISD NDDVLTFQAL
SDEDRRCWLN ALDGKEPFYS PTSGPCKPMQ TSLDNNSYKF VKALLERIEQ NFINEQGLYR
NCGINSKVQR LLQTALTTNS GNNNDFTTTT TTDSNDFSEW DAKTMTSAVK TFLRSLPEPL
MTHALHGQFL SASKLDSAKE RVEHIHYYVH QLPNENFRML KLLMHHLKRV AECASQNLMT
ACNLAVCFGP CVLRAEEETV AAIMDIKFYN LVVEVLIDNC DQIFEGEPKT FIASPPSKPP
HSCTRRSFDC CTGTFSPKSI LKTSENADTK IPADQTNDDV LSHDGVRVSS SSVSSSVSNG
EENIDESRTG SIGEFLDQLE NVSSFANSRG SASRTCVKYP RPYTSSKRRL FLNPKLTIPN
KTPPNRPHSP VSRAVSSSGL QASNRVRTLY ECVADCRCQL SFMPGQILTN VSKSKEPGWL
VGTLNGKPGL VPENFVEPLP
//
