ID A0A0V0S384_9BILA Unreviewed; 1382 AA.
AC A0A0V0S384;
DT 16-MAR-2016, integrated into UniProtKB/TrEMBL.
DT 16-MAR-2016, sequence version 1.
DT 27-MAR-2024, entry version 18.
DE SubName: Full=Rho GTPase-activating protein 7 {ECO:0000313|EMBL:KRX21164.1};
GN Name=DLC1 {ECO:0000313|EMBL:KRX21164.1};
GN ORFNames=T07_630 {ECO:0000313|EMBL:KRX21164.1};
OS Trichinella nelsoni.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Enoplea; Dorylaimia;
OC Trichinellida; Trichinellidae; Trichinella.
OX NCBI_TaxID=6336 {ECO:0000313|EMBL:KRX21164.1, ECO:0000313|Proteomes:UP000054630};
RN [1] {ECO:0000313|EMBL:KRX21164.1, ECO:0000313|Proteomes:UP000054630}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ISS37 {ECO:0000313|EMBL:KRX21164.1};
RA Korhonen P.K., Edoardo P., Giuseppe L.R., Gasser R.B.;
RT "Evolution of Trichinella species and genotypes.";
RL Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KRX21164.1}.
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DR EMBL; JYDL01000042; KRX21164.1; -; Genomic_DNA.
DR STRING; 6336.A0A0V0S384; -.
DR Proteomes; UP000054630; Unassembled WGS sequence.
DR GO; GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.
DR GO; GO:0008289; F:lipid binding; IEA:InterPro.
DR GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR Gene3D; 3.30.530.20; -; 1.
DR Gene3D; 1.10.555.10; Rho GTPase activation protein; 1.
DR InterPro; IPR008936; Rho_GTPase_activation_prot.
DR InterPro; IPR000198; RhoGAP_dom.
DR InterPro; IPR023393; START-like_dom_sf.
DR InterPro; IPR002913; START_lipid-bd_dom.
DR PANTHER; PTHR12659:SF7; CROSSVEINLESS C, ISOFORM C; 1.
DR PANTHER; PTHR12659; RHO-TYPE GTPASE ACTIVATING PROTEIN; 1.
DR Pfam; PF00620; RhoGAP; 1.
DR Pfam; PF01852; START; 1.
DR SMART; SM00324; RhoGAP; 1.
DR SMART; SM00234; START; 1.
DR SUPFAM; SSF55961; Bet v1-like; 1.
DR SUPFAM; SSF48350; GTPase activation domain, GAP; 1.
DR PROSITE; PS50238; RHOGAP; 1.
DR PROSITE; PS50848; START; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000054630}.
FT DOMAIN 935..1140
FT /note="Rho-GAP"
FT /evidence="ECO:0000259|PROSITE:PS50238"
FT DOMAIN 1194..1363
FT /note="START"
FT /evidence="ECO:0000259|PROSITE:PS50848"
FT REGION 73..111
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 540..562
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 638..681
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 73..91
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 638..673
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1382 AA; 152254 MW; 0A02A90FF6B81BA7 CRC64;
MDHITRSVAP VVTTATTVLP AGFSPVPAPR KRNALKAKKQ LEQSLLANVD GTGSRQIVAD
GRTVANAHAA SLHFSNNHNN NSNSSSLSVA RSRANDHHHH HHVVDQGSPP LRGLSERLLE
EAQSMPNCYQ FVQQTDTREL KGDIPACPAH QTSDIRLQFE IACAALHGVR ADLANSLASA
EDACIVAGGQ SSTDDALPAG PFDTKAYGKC KRPPPPPSTH NVRHRQAKCS EISISSPAAS
TVANPVVVLS TAHSIGYIGE SAKLQRYRFA HSSASRRSSS LEFTPVEEDS RIVVPMVRPT
SKSKRSAALE ILNGFGQGSQ IADEQSTNSC GSSSVFDASP PPHLSVRSVR HVVDKLIKQV
ESQIPRFRRS GGASRPTWAP PTQLDPDLVE TRRQAEMWTT DHTLSCDLMT GSVDDESRRN
VDACTQTSPL SLSCSSSFSW RSETDSIMAN GMSGELSNNG FLADNEISGP NSEGSPVMTT
TTPATAVATT TTTTTTALLS SSSSSAFAFS YSASSSSSSS SSCHSLSSVS DVADQKFATP
SATAAQLPSE SDRSSNGATK RLSSQQAFEE ALRLLLVAAA DDRFDDPKLA EILNVIREPT
TKPPNRPKPA TAGQQRCQVT FFEQPTARRS DHWTMSTLNN KSDENSVVSS LSPTFSSPET
QVRFHQSSTS RPDDPIAPHP ILRPDQSNLM SLSLSSSSSS KTVPGYGSKQ ACNKFSPDEQ
QVVVQQDDLV DGAVVGRFKS PQDDDGTRRK KKFSFSTVTG VISSGSNDDS SLDSDKWTPE
IRLATEKLSK TFTSKKTFEN GKKSAMDLGP PYKAGALIRS GTWLRREDSF AGDKRKSRVA
GITALARSKS LTARSRCFQD VHLPSLDGLQ IPVKIDALSV SQLTLTMKYA LLHLTSILEK
NVPYTKPTGF QFGVQRFFKR KKVPESTAST GVFGTALSVI VQRTGHPLPK CIYDAMKYIE
ANALDAVGIF RKSGVRSRIQ KLKSLCDDPS AEPVDFDQYQ AWDIADLIKL YFRELPDQLL
TTNLSETFIY ISLYVPESMK MDAIRKALLL LPDENREVLH TLLHFLHKIS QVSAVNQMDA
QNLAICLAPS LFYIRSMSTG HPNWRRKTIT TGFPSEKELK ENRAAQLCLG TMIRHYDQIF
QISEDVLRSC CFDKNIENRL HFVVSDQGAT FDLSNHYTVC CNSLIKEHND KWRGWIVEGS
WHGAEVTSKK ITDSFPLKLW RCWTEVEAPP KEVLFRILFE RKIWDPDMVS CRVVKKLTDR
CDVFQYMQQE TPPHLKRDFC TIRIWETDLP EFRGGCVLVA FSVNNEVTEL IGDVRANCLA
ARYVIEPAGR GRSRLTYISR IDLRGRCKTW YNRNFGPLCA RQIAQIRDSF LLQLAPGPET
RL
//
