ID   A0A0V0S4K9_9BILA        Unreviewed;       874 AA.
AC   A0A0V0S4K9;
DT   16-MAR-2016, integrated into UniProtKB/TrEMBL.
DT   16-MAR-2016, sequence version 1.
DT   24-JAN-2024, entry version 14.
DE   SubName: Full=Cysteine-rich motor neuron 1 protein {ECO:0000313|EMBL:KRX21694.1};
GN   Name=CRIM1 {ECO:0000313|EMBL:KRX21694.1};
GN   ORFNames=T07_14569 {ECO:0000313|EMBL:KRX21694.1};
OS   Trichinella nelsoni.
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Enoplea; Dorylaimia;
OC   Trichinellida; Trichinellidae; Trichinella.
OX   NCBI_TaxID=6336 {ECO:0000313|EMBL:KRX21694.1, ECO:0000313|Proteomes:UP000054630};
RN   [1] {ECO:0000313|EMBL:KRX21694.1, ECO:0000313|Proteomes:UP000054630}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ISS37 {ECO:0000313|EMBL:KRX21694.1};
RA   Korhonen P.K., Edoardo P., Giuseppe L.R., Gasser R.B.;
RT   "Evolution of Trichinella species and genotypes.";
RL   Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KRX21694.1}.
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DR   EMBL; JYDL01000037; KRX21694.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A0V0S4K9; -.
DR   Proteomes; UP000054630; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0004867; F:serine-type endopeptidase inhibitor activity; IEA:InterPro.
DR   Gene3D; 6.20.200.20; -; 6.
DR   InterPro; IPR004094; Antistasin-like.
DR   InterPro; IPR011061; Hirudin/antistatin.
DR   InterPro; IPR001007; VWF_dom.
DR   PANTHER; PTHR46439; CYSTEINE-RICH MOTOR NEURON 1 PROTEIN; 1.
DR   PANTHER; PTHR46439:SF1; CYSTEINE-RICH MOTOR NEURON 1 PROTEIN; 1.
DR   Pfam; PF02822; Antistasin; 3.
DR   Pfam; PF00093; VWC; 4.
DR   SMART; SM00214; VWC; 6.
DR   SUPFAM; SSF57603; FnI-like domain; 5.
DR   SUPFAM; SSF57262; Leech antihemostatic proteins; 1.
DR   PROSITE; PS51252; ANTISTASIN; 2.
DR   PROSITE; PS01208; VWFC_1; 4.
DR   PROSITE; PS50184; VWFC_2; 6.
PE   4: Predicted;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000054630};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        786..810
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          220..279
FT                   /note="VWFC"
FT                   /evidence="ECO:0000259|PROSITE:PS50184"
FT   DOMAIN          279..337
FT                   /note="VWFC"
FT                   /evidence="ECO:0000259|PROSITE:PS50184"
FT   DOMAIN          348..374
FT                   /note="Antistasin-like"
FT                   /evidence="ECO:0000259|PROSITE:PS51252"
FT   DOMAIN          450..476
FT                   /note="Antistasin-like"
FT                   /evidence="ECO:0000259|PROSITE:PS51252"
FT   DOMAIN          498..554
FT                   /note="VWFC"
FT                   /evidence="ECO:0000259|PROSITE:PS50184"
FT   DOMAIN          565..624
FT                   /note="VWFC"
FT                   /evidence="ECO:0000259|PROSITE:PS50184"
FT   DOMAIN          639..698
FT                   /note="VWFC"
FT                   /evidence="ECO:0000259|PROSITE:PS50184"
FT   DOMAIN          704..760
FT                   /note="VWFC"
FT                   /evidence="ECO:0000259|PROSITE:PS50184"
SQ   SEQUENCE   874 AA;  97081 MW;  8064EAB804B605B1 CRC64;
     MENPNMLNCS APSLYHGCSL FLKHGCSCLT VKSCQQAHFQ FSDEAICHEE WIRRKTMWKE
     VCLKAKCGVV FQPKCPEDSI LVPAPAPEPP NCCPSPDTCQ CSQEACLKHI KSCPPESELV
     RVSEGTDTPG RCCDIFECFP KKFGCNHVRC PPTKVEKCPE DSYRPPQVIA EKGCCPVVEE
     CRCLAGVCPP AVCPPNHHLV VLKKGNGIPG MEPAVNETSM ICEVEKTVFH NGDTWHPKPC
     TECECKDGII FCRSLLCHPP PPSCRRIQVP EGECCPICSG CETENGESRN ITEQWKKDDC
     TTCQCSEDGQ VICQRQLCSV ECDNPLYVSG QCCPVCEKSL LINLPLSCPS IELCTLRCEY
     GLKRGLDGCF LCECQQNLQH LSGAEDEHHG NFMSVKISEP ITAEKVEVLP LEPGSKSGCQ
     FWNLQSCTKR CAHGFEHDAN GCPMCKCNAC PRIYNCNKHC LYGYEKNLHG CEICRCRGIW
     IESDSSIFPT KNSTSEWIGC SSLAGYRDHG EWWFDDCRHC YCDHGREFCS LLACPHLNCT
     EPTFIDGECC PRCPDAALDR RLHRLTCHAP GGNRNYVEGE FWNLDKCTIC TCHVGHVLCH
     RKECPPAPCA KPSISDDTCC PVCRDIGFGE FTPPANISSF CSTETGVAHV EGSVWKEGPC
     VSCVCRHSQV RCYYQSCASV TCDSRSLHLK DSCCPICMEK MDTGVCHLNG VSYNIGEMWR
     DNICRNCTCQ YGGELFCSQM ECRKCVEPIY KEGLCCPVCK EMTNWQVLPN YPKLNDNSTD
     VQQASLVVAL CIIGILAVVL LIVLLVVWLA KKYRAPAIAK STEARLSSLK FQQGKSLLKH
     IKRNGAYKQR KNVSLLRETG GSCEEPECAS DAAV
//