ID A0A0V0S8C2_9BILA Unreviewed; 377 AA.
AC A0A0V0S8C2;
DT 16-MAR-2016, integrated into UniProtKB/TrEMBL.
DT 16-MAR-2016, sequence version 1.
DT 27-MAR-2024, entry version 20.
DE SubName: Full=Carnitine O-palmitoyltransferase 2, mitochondrial {ECO:0000313|EMBL:KRX22969.1};
GN Name=Cpt2 {ECO:0000313|EMBL:KRX22969.1};
GN ORFNames=T07_1920 {ECO:0000313|EMBL:KRX22969.1};
OS Trichinella nelsoni.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Enoplea; Dorylaimia;
OC Trichinellida; Trichinellidae; Trichinella.
OX NCBI_TaxID=6336 {ECO:0000313|EMBL:KRX22969.1, ECO:0000313|Proteomes:UP000054630};
RN [1] {ECO:0000313|EMBL:KRX22969.1, ECO:0000313|Proteomes:UP000054630}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ISS37 {ECO:0000313|EMBL:KRX22969.1};
RA Korhonen P.K., Edoardo P., Giuseppe L.R., Gasser R.B.;
RT "Evolution of Trichinella species and genotypes.";
RL Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=(R)-carnitine + 4,8-dimethylnonanoyl-CoA = CoA + O-4,8-
CC dimethylnonanoyl-(R)-carnitine; Xref=Rhea:RHEA:44860,
CC ChEBI:CHEBI:16347, ChEBI:CHEBI:57287, ChEBI:CHEBI:77061,
CC ChEBI:CHEBI:84654; Evidence={ECO:0000256|ARBA:ARBA00024283};
CC -!- PATHWAY: Lipid metabolism; fatty acid beta-oxidation.
CC {ECO:0000256|ARBA:ARBA00005005}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KRX22969.1}.
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DR EMBL; JYDL01000027; KRX22969.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0V0S8C2; -.
DR UniPathway; UPA00659; -.
DR Proteomes; UP000054630; Unassembled WGS sequence.
DR GO; GO:0016746; F:acyltransferase activity; IEA:UniProtKB-KW.
DR GO; GO:0006635; P:fatty acid beta-oxidation; IEA:UniProtKB-UniPathway.
DR Gene3D; 1.20.1280.180; -; 1.
DR Gene3D; 1.10.275.20; Choline/Carnitine o-acyltransferase; 1.
DR Gene3D; 3.30.559.70; Choline/Carnitine o-acyltransferase, domain 2; 1.
DR InterPro; IPR000542; Carn_acyl_trans.
DR InterPro; IPR042572; Carn_acyl_trans_N.
DR InterPro; IPR039551; Cho/carn_acyl_trans.
DR InterPro; IPR042231; Cho/carn_acyl_trans_2.
DR PANTHER; PTHR22589; CARNITINE O-ACYLTRANSFERASE; 1.
DR PANTHER; PTHR22589:SF16; CARNITINE O-PALMITOYLTRANSFERASE 2, MITOCHONDRIAL; 1.
DR Pfam; PF00755; Carn_acyltransf; 1.
DR SUPFAM; SSF52777; CoA-dependent acyltransferases; 1.
PE 4: Predicted;
KW Acyltransferase {ECO:0000256|ARBA:ARBA00023315};
KW Reference proteome {ECO:0000313|Proteomes:UP000054630};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000313|EMBL:KRX22969.1}.
FT DOMAIN 89..368
FT /note="Choline/carnitine acyltransferase"
FT /evidence="ECO:0000259|Pfam:PF00755"
SQ SEQUENCE 377 AA; 43748 MW; F98355580C33DCED CRC64;
MPRGSGFDNS VIAVAAVCSK QAGIDYDIEV ADSFLTKMKA KLGDRLEFSQ RSSEKINNNR
DQEPHDMAYQ FLERSKIPTM HFQDGLPRLP IPKLKYTCQN YLNGIRPFLN DEQFDAAKKL
VDDFRHSSGE RLNRELILWY RRNKHTSYIA EPWFDMYFRY RAALPINQNP FLVWKPYNES
FNNDQLSVAT NIVISACRFK RSLDYNCLQP EVYHLHPNKS NTPFFRNICS RLPGKLAWLI
AFLMKAFPLD MSQYSFLFNT TRIPVMIKDQ LNTNRSSKCI IVLRRGYFYS LTVFRKDGSL
ISPAEIHASL EYILKDNRPV AENPVGLLTT VDREQWSLLR SQLLMIDGNE RSLLTIDGGL
FVLNLDELQS IDPETMV
//
