ID A0A0V0SAL4_9BILA Unreviewed; 866 AA.
AC A0A0V0SAL4;
DT 16-MAR-2016, integrated into UniProtKB/TrEMBL.
DT 16-MAR-2016, sequence version 1.
DT 13-SEP-2023, entry version 28.
DE RecName: Full=RBR-type E3 ubiquitin transferase {ECO:0000256|ARBA:ARBA00012251};
DE EC=2.3.2.31 {ECO:0000256|ARBA:ARBA00012251};
GN ORFNames=T07_11537 {ECO:0000313|EMBL:KRX23722.1};
OS Trichinella nelsoni.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Enoplea; Dorylaimia;
OC Trichinellida; Trichinellidae; Trichinella.
OX NCBI_TaxID=6336 {ECO:0000313|EMBL:KRX23722.1, ECO:0000313|Proteomes:UP000054630};
RN [1] {ECO:0000313|EMBL:KRX23722.1, ECO:0000313|Proteomes:UP000054630}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ISS37 {ECO:0000313|EMBL:KRX23722.1};
RA Korhonen P.K., Edoardo P., Giuseppe L.R., Gasser R.B.;
RT "Evolution of Trichinella species and genotypes.";
RL Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=[E2 ubiquitin-conjugating enzyme]-S-ubiquitinyl-L-cysteine +
CC [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-
CC cysteine + [acceptor protein]-N(6)-ubiquitinyl-L-lysine.;
CC EC=2.3.2.31; Evidence={ECO:0000256|ARBA:ARBA00001798};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KRX23722.1}.
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DR EMBL; JYDL01000022; KRX23722.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0V0SAL4; -.
DR STRING; 6336.A0A0V0SAL4; -.
DR Proteomes; UP000054630; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0004842; F:ubiquitin-protein transferase activity; IEA:InterPro.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR GO; GO:0016567; P:protein ubiquitination; IEA:InterPro.
DR CDD; cd20338; BRcat_RBR_RNF19; 1.
DR CDD; cd20355; Rcat_RBR_RNF19; 1.
DR Gene3D; 1.20.120.1750; -; 1.
DR Gene3D; 2.20.25.20; -; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR031127; E3_UB_ligase_RBR.
DR InterPro; IPR002867; IBR_dom.
DR InterPro; IPR044066; TRIAD_supradom.
DR InterPro; IPR001841; Znf_RING.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR PANTHER; PTHR11685; RBR FAMILY RING FINGER AND IBR DOMAIN-CONTAINING; 1.
DR PANTHER; PTHR11685:SF427; RBR-TYPE E3 UBIQUITIN TRANSFERASE; 1.
DR Pfam; PF01485; IBR; 2.
DR SMART; SM00647; IBR; 2.
DR SUPFAM; SSF57850; RING/U-box; 3.
DR PROSITE; PS51873; TRIAD; 1.
DR PROSITE; PS50089; ZF_RING_2; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000054630};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius};
KW Ubl conjugation pathway {ECO:0000256|ARBA:ARBA00022786};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00175}.
FT TRANSMEM 394..423
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 444..477
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 167..384
FT /note="RING-type"
FT /evidence="ECO:0000259|PROSITE:PS51873"
FT DOMAIN 171..220
FT /note="RING-type"
FT /evidence="ECO:0000259|PROSITE:PS50089"
SQ SEQUENCE 866 AA; 95180 MW; 227FB1693049C59E CRC64;
MGVCPVKVSK TLAALVKRSP DSPTQMFKQS LRMRRFRIGF KLLSYTYSVA FEMKKRVGQM
RSGEILMHER LVNDDKKGDM STQSAARKSA LFRFGRRAKR KSKKAVAVDS SKERNFAADM
VEGVGHSSAD CGSSSVHGQS VFPMQPTPDS FCNDQQASAL PSVSKGATKE CPVCVTRQPI
EQFPRLICCN HRACLSCLIE VRHALQILES RVNLTCYECN EMLHPDDVYS ILKNKPHLIE
KYEEFSVRRV LMSDPDTRWC PAPDCSYAVI ASGCAACPEI KCERIGCGAS FCYHCKMIWH
SNQTCDEAKA SRRSVADSPM QIDVNVKPGD LKACPRCKTY IVKMNDGSCN HMICALCGVE
FCWLCLREIS DLHYLSPSGC TFWGKKPWSR KKKLIWQVSM LVGAPVGIAL VAGLAVPAII
FGFPVWIGRK IHQRLKYSTK FKRILAILGG VAGGVVLSPV LASLAISVGV PILLAYVYGV
VLVSLCRNGY CGVNSSNSGV RLDSDETVVS SAVRNELMQE RAFLLREVDR QDSENFITSV
SSDASGQNSI QIQVDVCDST VPAAERHSRF NVEALSTKTF ETACFDDKSI RTYDSFADTC
NVSLQEGDSL KGLHGSLGFP CVDEEAKSTA NFAAAVQRFQ DSTTLKCDCT DVNSSTINGN
TAVELSSCRG LDSLVLAFAD EQSASSGNQS PSEKIEELDN ESSRILLSCQ SDESHSKLSC
KHRLRNSSAE GEGEFLLLPS DAVLWKSGKP LLSEMKMSKS SSTLSQRPSA ASTVLNSILE
MASDSTAALD RTARGLFTSV DRSMGAGRRR FSVLFRKEKN ATDPMPTILP DFLDHEDISR
SMPNMNSSTC QLRSQLYDDQ AQRGDF
//
