ID A0A0V0SKF3_9BILA Unreviewed; 426 AA.
AC A0A0V0SKF3;
DT 16-MAR-2016, integrated into UniProtKB/TrEMBL.
DT 16-MAR-2016, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE SubName: Full=tRNA pseudouridine(38/39) synthase {ECO:0000313|EMBL:KRX27230.1};
GN Name=Pus3 {ECO:0000313|EMBL:KRX27230.1};
GN ORFNames=T07_5000 {ECO:0000313|EMBL:KRX27230.1};
OS Trichinella nelsoni.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Enoplea; Dorylaimia;
OC Trichinellida; Trichinellidae; Trichinella.
OX NCBI_TaxID=6336 {ECO:0000313|EMBL:KRX27230.1, ECO:0000313|Proteomes:UP000054630};
RN [1] {ECO:0000313|EMBL:KRX27230.1, ECO:0000313|Proteomes:UP000054630}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ISS37 {ECO:0000313|EMBL:KRX27230.1};
RA Korhonen P.K., Edoardo P., Giuseppe L.R., Gasser R.B.;
RT "Evolution of Trichinella species and genotypes.";
RL Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the tRNA pseudouridine synthase TruA family.
CC {ECO:0000256|ARBA:ARBA00009375}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KRX27230.1}.
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DR EMBL; JYDL01000004; KRX27230.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0V0SKF3; -.
DR Proteomes; UP000054630; Unassembled WGS sequence.
DR GO; GO:0009982; F:pseudouridine synthase activity; IEA:InterPro.
DR GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR GO; GO:0001522; P:pseudouridine synthesis; IEA:InterPro.
DR GO; GO:0008033; P:tRNA processing; IEA:UniProtKB-KW.
DR CDD; cd02569; PseudoU_synth_ScPus3; 1.
DR Gene3D; 3.30.70.660; Pseudouridine synthase I, catalytic domain, C-terminal subdomain; 1.
DR Gene3D; 3.30.70.580; Pseudouridine synthase I, catalytic domain, N-terminal subdomain; 1.
DR HAMAP; MF_00171; TruA; 1.
DR InterPro; IPR020103; PsdUridine_synth_cat_dom_sf.
DR InterPro; IPR001406; PsdUridine_synth_TruA.
DR InterPro; IPR020097; PsdUridine_synth_TruA_a/b_dom.
DR InterPro; IPR020095; PsdUridine_synth_TruA_C.
DR InterPro; IPR041707; Pus3-like.
DR InterPro; IPR020094; TruA/RsuA/RluB/E/F_N.
DR NCBIfam; TIGR00071; hisT_truA; 1.
DR PANTHER; PTHR11142; PSEUDOURIDYLATE SYNTHASE; 1.
DR PANTHER; PTHR11142:SF5; TRNA PSEUDOURIDINE(38_39) SYNTHASE; 1.
DR Pfam; PF01416; PseudoU_synth_1; 1.
DR SUPFAM; SSF55120; Pseudouridine synthase; 1.
PE 3: Inferred from homology;
KW Isomerase {ECO:0000256|ARBA:ARBA00023235};
KW Reference proteome {ECO:0000313|Proteomes:UP000054630};
KW tRNA processing {ECO:0000256|ARBA:ARBA00022694}.
FT DOMAIN 193..307
FT /note="Pseudouridine synthase I TruA alpha/beta"
FT /evidence="ECO:0000259|Pfam:PF01416"
FT REGION 116..135
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 392..426
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 408..426
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 426 AA; 48804 MW; 7BD08FBC8F696591 CRC64;
MKLCCKLKTA TGIIKPYEMP RKDERQFDFS RYCRRHIALM VAYLGWDLDG FCAQNNSQNT
VESKIFKALI ETKLIQSLET ANYSRCGRTD KTVSAFSQVL SLDVRSNQTT GVGVFEPDGY
CPNEPKPTSR KTTPKSEELD YAKILNSVLP QEIRVLAWAP VERTFNARYN CTSRQYKYFF
PKGALNLKLM EQASKRLIGE HDFRNFCKID MSKNEIQSCV RTVFDVQFTK VNAGGLNSRR
LCCFTIVANA FLWHQIRCIM SVLFAIGEGK EQPDVIEWLL NTELCPAKPQ YSMVVGWPLV
LYGCQYDNLE WHWKEGIIME CISSLQRTWV NFAIKIEIIE NMMNSLLSLM PNSSTTADLN
TTSILHPELL SHSYRPLKGR SVGKSLEEKI AKKKKQQLGT KRTTADDTTK QSLNEEEEEA
VENLSR
//
