ID A0A0V0TAQ6_9BILA Unreviewed; 781 AA.
AC A0A0V0TAQ6;
DT 16-MAR-2016, integrated into UniProtKB/TrEMBL.
DT 16-MAR-2016, sequence version 1.
DT 24-JAN-2024, entry version 28.
DE SubName: Full=Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 2 {ECO:0000313|EMBL:KRX36033.1};
GN Name=Acap2 {ECO:0000313|EMBL:KRX36033.1};
GN ORFNames=T05_16068 {ECO:0000313|EMBL:KRX36033.1};
OS Trichinella murrelli.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Enoplea; Dorylaimia;
OC Trichinellida; Trichinellidae; Trichinella.
OX NCBI_TaxID=144512 {ECO:0000313|EMBL:KRX36033.1, ECO:0000313|Proteomes:UP000055048};
RN [1] {ECO:0000313|EMBL:KRX36033.1, ECO:0000313|Proteomes:UP000055048}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ISS417 {ECO:0000313|EMBL:KRX36033.1};
RA Korhonen P.K., Edoardo P., Giuseppe L.R., Gasser R.B.;
RT "Evolution of Trichinella species and genotypes.";
RL Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KRX36033.1}.
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DR EMBL; JYDJ01000390; KRX36033.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0V0TAQ6; -.
DR STRING; 144512.A0A0V0TAQ6; -.
DR Proteomes; UP000055048; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:InterPro.
DR GO; GO:0005096; F:GTPase activator activity; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR CDD; cd08835; ArfGap_ACAP; 1.
DR CDD; cd13250; PH_ACAP; 1.
DR Gene3D; 1.25.40.20; Ankyrin repeat-containing domain; 1.
DR Gene3D; 1.10.220.150; Arf GTPase activating protein; 1.
DR Gene3D; 1.20.1270.60; Arfaptin homology (AH) domain/BAR domain; 1.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR InterPro; IPR045258; ACAP1/2/3-like.
DR InterPro; IPR027267; AH/BAR_dom_sf.
DR InterPro; IPR002110; Ankyrin_rpt.
DR InterPro; IPR036770; Ankyrin_rpt-contain_sf.
DR InterPro; IPR037278; ARFGAP/RecO.
DR InterPro; IPR001164; ArfGAP_dom.
DR InterPro; IPR038508; ArfGAP_dom_sf.
DR InterPro; IPR004148; BAR_dom.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR001849; PH_domain.
DR PANTHER; PTHR23180:SF399; BLOWN FUSE, ISOFORM A-RELATED; 1.
DR PANTHER; PTHR23180; CENTAURIN/ARF; 1.
DR Pfam; PF12796; Ank_2; 1.
DR Pfam; PF01412; ArfGap; 1.
DR Pfam; PF16746; BAR_3; 1.
DR Pfam; PF00169; PH; 1.
DR PRINTS; PR00405; REVINTRACTNG.
DR SMART; SM00248; ANK; 3.
DR SMART; SM00105; ArfGap; 1.
DR SMART; SM00233; PH; 1.
DR SUPFAM; SSF48403; Ankyrin repeat; 1.
DR SUPFAM; SSF57863; ArfGap/RecO-like zinc finger; 1.
DR SUPFAM; SSF103657; BAR/IMD domain-like; 1.
DR SUPFAM; SSF50729; PH domain-like; 1.
DR PROSITE; PS50297; ANK_REP_REGION; 1.
DR PROSITE; PS50088; ANK_REPEAT; 2.
DR PROSITE; PS50115; ARFGAP; 1.
DR PROSITE; PS50003; PH_DOMAIN; 1.
PE 4: Predicted;
KW ANK repeat {ECO:0000256|ARBA:ARBA00023043, ECO:0000256|PROSITE-
KW ProRule:PRU00023}; Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000055048};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00288}.
FT DOMAIN 267..375
FT /note="PH"
FT /evidence="ECO:0000259|PROSITE:PS50003"
FT DOMAIN 398..524
FT /note="Arf-GAP"
FT /evidence="ECO:0000259|PROSITE:PS50115"
FT REPEAT 651..683
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 684..716
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
SQ SEQUENCE 781 AA; 89169 MW; 08168A01B54F3EC0 CRC64;
MGTYNLDALN AAEALKNSPH FKWQLAQHES YLQMYDTKIL ELLRWTNDMI EKGKAYVDSF
QHFLGAFADM NVTCFSHDQT ASSSLQMTLA LLNEVAKYQK VFVEQIYWSL VKNLEEIRKR
DLSKVYEMRS HFQRVSRSLD DALWKNAHVS KLKDHEGSDA KNELTAVGTC FAHTCLDYIF
QINLVHASKK HEILEAFLSF VYATETFFHQ GYDLFGPEWL ETKNQMVETL SYFKAQEKQT
ERKMQDRHAL VPREIFQHPP SISLDPDIVM EGYLFKRSSR TIKTWNRRWF IIKNNKLVYF
RREVDFSSPA FLTNFYNFCT VMEDDLRLCL VRPAPAACDR RFCFEVVTPH KTHMLQADSE
SLRAAWISAL QRTIEAALHY GSLNSSSSCS GSDTMHKSQS SHAITTADEI LNVCGNQQCA
DCGSKNPKWA SVNLGITLCI ECCGIHRSLG VQVSKVRSLT LDAWEPDQVH LMLLLGNEKV
NRIFMAFRPD FSYLMPNSPR FAREAWIKAK YLKRRFMKSF AYQDRLYQRH LIFCSGTDQL
VLHGLALRYY EFSSSSFPSV DCCGCEGFAN ARELGGRRTT DLTISNERAH ARRSWVSEST
LNFSELDSAL CTEIRQQTDK LLLATKNDDI LAMFQAIASG ASLNFSDGNS EKKTALHEAV
CRNSSTSCEL LFLNGARINV CDIHQRTPLH YACLLGSAAM VLYLLKRGAD QGVCDKSGKT
PLDIAIEQAN ADIVTLLRLA KLNDEFKDEY SSSSELNFSS VCRDFTLAYS KPDILNRPKE
Y
//
