ID A0A0V0TC74_9BILA Unreviewed; 2511 AA.
AC A0A0V0TC74;
DT 16-MAR-2016, integrated into UniProtKB/TrEMBL.
DT 16-MAR-2016, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE SubName: Full=Putative neurobeachin-like protein {ECO:0000313|EMBL:KRX36620.1};
GN Name=sel-2 {ECO:0000313|EMBL:KRX36620.1};
GN ORFNames=T05_10559 {ECO:0000313|EMBL:KRX36620.1};
OS Trichinella murrelli.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Enoplea; Dorylaimia;
OC Trichinellida; Trichinellidae; Trichinella.
OX NCBI_TaxID=144512 {ECO:0000313|EMBL:KRX36620.1, ECO:0000313|Proteomes:UP000055048};
RN [1] {ECO:0000313|EMBL:KRX36620.1, ECO:0000313|Proteomes:UP000055048}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ISS417 {ECO:0000313|EMBL:KRX36620.1};
RA Korhonen P.K., Edoardo P., Giuseppe L.R., Gasser R.B.;
RT "Evolution of Trichinella species and genotypes.";
RL Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KRX36620.1}.
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DR EMBL; JYDJ01000352; KRX36620.1; -; Genomic_DNA.
DR Proteomes; UP000055048; Unassembled WGS sequence.
DR CDD; cd06071; Beach; 1.
DR CDD; cd01201; PH_BEACH; 1.
DR Gene3D; 2.60.120.200; -; 1.
DR Gene3D; 1.10.1540.10; BEACH domain; 1.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 2.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR000409; BEACH_dom.
DR InterPro; IPR036372; BEACH_dom_sf.
DR InterPro; IPR013320; ConA-like_dom_sf.
DR InterPro; IPR046851; NBCH_WD40.
DR InterPro; IPR010508; NBEA-like_DUF1088.
DR InterPro; IPR031570; NBEA/BDCP_DUF4704.
DR InterPro; IPR046852; Neurobeachin_a-sol.
DR InterPro; IPR023362; PH-BEACH_dom.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR InterPro; IPR036322; WD40_repeat_dom_sf.
DR InterPro; IPR001680; WD40_rpt.
DR PANTHER; PTHR13743; BEIGE/BEACH-RELATED; 1.
DR PANTHER; PTHR13743:SF160; NEUROBEACHIN; 1.
DR Pfam; PF02138; Beach; 1.
DR Pfam; PF06469; DUF1088; 1.
DR Pfam; PF15787; DUF4704; 1.
DR Pfam; PF13385; Laminin_G_3; 1.
DR Pfam; PF20426; NBCH_WD40; 1.
DR Pfam; PF20425; Neurobeachin; 1.
DR Pfam; PF14844; PH_BEACH; 1.
DR SMART; SM01026; Beach; 1.
DR SMART; SM00320; WD40; 4.
DR SUPFAM; SSF48371; ARM repeat; 1.
DR SUPFAM; SSF81837; BEACH domain; 1.
DR SUPFAM; SSF49899; Concanavalin A-like lectins/glucanases; 1.
DR SUPFAM; SSF50729; PH domain-like; 1.
DR SUPFAM; SSF50978; WD40 repeat-like; 1.
DR PROSITE; PS50197; BEACH; 1.
DR PROSITE; PS51783; PH_BEACH; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000055048};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW WD repeat {ECO:0000256|ARBA:ARBA00022574}.
FT DOMAIN 1697..1805
FT /note="BEACH-type PH"
FT /evidence="ECO:0000259|PROSITE:PS51783"
FT DOMAIN 1824..2103
FT /note="BEACH"
FT /evidence="ECO:0000259|PROSITE:PS50197"
FT REGION 1334..1361
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1382..1414
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1623..1651
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1382..1404
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 2511 AA; 283035 MW; 08F72A2FBEBFD882 CRC64;
MFEHGADFSE LDLEGNLLTR ASVEGNSTSD VVSLTVDTTP GEVQNGADCN ENGSVLKSSF
QHAPQNAKKE NTTESCKENN NCMKSETAEQ MFSRLKMGLK DGKIAGKELV DSVFQLLVGG
PFNMENAFLI QNKEYIIPMV YLLDAICIFS AEMWCVFIGI ARKSHRNLEA CAESGLIRAL
LGRLPDAEDV VADFLIELLT ILTTYSINVK DMKMLLRALR AVDDKWPRHS AKLLLVIKQM
LRKEGPDVFF SFFGGSKTGI HIPPLSKWPY QNGWSFVTWV RLDPESSATF EEETPYLFSF
RTRNGLGHSC HFVGNCMVVT TVKNKNGQSV QQCIKYELQV RKWYHVVLAY SYSRWGRSEL
QCFVNGQPVS GFEFNWHVST NEYDRCFVGC CPDSNGKNSF SGQMSVLYLF SESLNLQQVN
SLYGLGPNYQ SCFKFKNEVD IPIAYMKYLF DGKLSSALVF AYSPQNCDRQ LCLNSVMKEN
QGYFFQTPHA VMMDGVNVVV THSIHTTLHS VGGVQVFLPL LTQLDFPVQT SCDHSTLLSI
FSQLMVCSPG VQQQLLQTNA FLVIGVSLTA ADKKHITESV LNTFIEMAHF LISPESSSAN
LLRQLFEFVL LNPNLWINTD GRVSLVCLWV QTRLYQYLAT DFYDKAKIFN PVRRVTTIMQ
LLHSLKFYYW VTDPRRRSGI DGKGKAGPRP TVDNILTIRA HILTLMYKIV SNNEPGAQTG
DELKAILNFL TTVHEDDNLT DVLSMLIKLV AANPAMLIPA FDKKRGVWVV FKLIGAANET
VRLLALKLFG FFLCRCTSKR KQDTMNPYNL YTLLTDRLLL HATYINVRTY NVLFEILIEK
MTSDILDGRH PEPSTNCKFE NPMLIRTIAS LLQQSDQQNT EVLEVKKVFL TDLIHMCTNS
SENRRIILQM SVWQDWLISL TSLEPNTEAE MHIRSLVYHL FAILLHHAIK LEYGGWRVWI
DTMAIIHSKG SFERFCRKNS GKAVSRLDMT QSEKNDDVEK EVVTVVQDLL SKVAGQSSTV
ASDESQSVFS TSNVSSESTY VGSRSEEKAS QQADSTVPLY RIPEFRWSAA HLTLLSDLLL
GIESDIAVWK NDGSRSLIDY INQSDNAVFV VNAIHVMSQS LDSFIVACGG LLPLLAALTS
PSSDLEIADT SNQGLSMNVA ISFLVRLANL ADVIVFGTAC NFADLEREKN MPTGGILRQI
LRLVTMVAVR NCLVYRYKSC FDHQLVVCAK ERAIKALVDD LTSLDETNSD FLNLKTTVQD
PERVLQEVDV YRLKATLYRD IEESRQAQFL ALATIYFLSV LMVSRYRDIL EPPSSPSPFH
NTVSAGSNFN QTAEYRKDNS KIVPSEAKTS VKNENDEQSL LSGAKSAADG FHDLTDSIRL
KQDENVSNSP MATVETAPPK SDQSSSKDDA SKERQALLSA RLRTALEPVA PLFREIIADF
QSYFQKTLLG THGQEIMNDP KGIGVRFVLN TLRNSNVSVI ELVMLLCSQE WQTSVQKHAG
LAFIELVNEG RLLAHATRDH LVRVANEAEY ILNRMRAEDV MKHAEFEAMC AQLVVTSKEE
ESTCNLLISA ARRRNTMISR KILDKVHVIL RSEYGAWGVE NRAKMFWKLD IWEDDSRRRR
RLVPNSFGSS HPEATLKSAD NQGEDESEVE KTRDAFASYL RDKNIVLPSS TPSSLTNELL
TETEIVLWNE ETDEEVNQQA GSCFITPCHL VAPGLVLPGI LSITANELSF DCKDDDAELQ
QADPAILRYC EHLHGRWHTA EIRAIFLRRH LLQNRALEIF LTSRTAIMFA FPDQNTVKKV
VQRLPAVGVG QKYGIAQSRK ASLMTPRQLF KHSDMPQKWQ RREICNFEYL MFLNTIAGRT
YNDLNQYPVF PWILSNYDSE ELDLKQPANF RDLSKPVGAL NDSRRKYFID RYRQWEHDKI
PPFHYGTHYS TAAFTMNWLM RMEPFTSLFL SLQSGKFDHA DRMFHSVAES WKHCLRDTHD
VKELIPEFFY LPEMFLNING YQLGKRDDGS LVGDVILPPW AKSPEHFITI HRQLHQWIDL
IFGYKQRGPE AVRATNVFYY LTYEGVVDLS SFDDPMIKKA LENQIRNFGQ TPAQLLSEPH
TPRQSIMTIS PLMFQPVPDD ICMIMKFISN SAVVHLSANT HAQLPNPTVV SITASLGFAL
NRWNNNYSGN FGSHLAPVGV ETAGSTQNLV PPNLPLTVDP LLATGNPASP VARRMLGDSL
DQHLTIKWNN FVTTCDSKYI FVCGYPDHSF RVIETENARI RQVIFGHKSV VTCLARSEAS
TGIDFYIASG SSDCTVLLWQ WNVKSSFVVG EQNITGESAS PRVILIGHDS EITCIHVSAE
HGLVLSTSVG GPLLIHTTQG DLLRCLRPAE QDQQQHSVGS PRILLMSREC YAVVCYDLGN
LCLFTTNGRL ISQLKTASHI TCMCLSRDGE YFVTGSEEGT VSVYATVDLK CLYAYSACDG
AAVRSVAIVY NHRHIVAGLS NGAIVVYNVD FNKWHHEYRH RYVLLSNSRD Q
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