ID A0A0V0TD50_9BILA Unreviewed; 1986 AA.
AC A0A0V0TD50;
DT 16-MAR-2016, integrated into UniProtKB/TrEMBL.
DT 16-MAR-2016, sequence version 1.
DT 27-MAR-2024, entry version 20.
DE SubName: Full=Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1 {ECO:0000313|EMBL:KRX36881.1};
GN ORFNames=T05_2738 {ECO:0000313|EMBL:KRX36881.1};
OS Trichinella murrelli.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Enoplea; Dorylaimia;
OC Trichinellida; Trichinellidae; Trichinella.
OX NCBI_TaxID=144512 {ECO:0000313|EMBL:KRX36881.1, ECO:0000313|Proteomes:UP000055048};
RN [1] {ECO:0000313|EMBL:KRX36881.1, ECO:0000313|Proteomes:UP000055048}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ISS417 {ECO:0000313|EMBL:KRX36881.1};
RA Korhonen P.K., Edoardo P., Giuseppe L.R., Gasser R.B.;
RT "Evolution of Trichinella species and genotypes.";
RL Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KRX36881.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; JYDJ01000339; KRX36881.1; -; Genomic_DNA.
DR STRING; 144512.A0A0V0TD50; -.
DR Proteomes; UP000055048; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProt.
DR GO; GO:0012505; C:endomembrane system; IEA:UniProt.
DR GO; GO:0043231; C:intracellular membrane-bounded organelle; IEA:UniProt.
DR GO; GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:InterPro.
DR GO; GO:0051641; P:cellular localization; IEA:UniProt.
DR GO; GO:0032012; P:regulation of ARF protein signal transduction; IEA:InterPro.
DR GO; GO:0016192; P:vesicle-mediated transport; IEA:UniProt.
DR CDD; cd00171; Sec7; 1.
DR Gene3D; 1.10.220.20; -; 1.
DR Gene3D; 1.10.1000.11; Arf Nucleotide-binding Site Opener,domain 2; 1.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR010414; FRG1.
DR InterPro; IPR032691; Mon2/Sec7/BIG1-like_HUS.
DR InterPro; IPR023394; Sec7_C_sf.
DR InterPro; IPR000904; Sec7_dom.
DR InterPro; IPR035999; Sec7_dom_sf.
DR PANTHER; PTHR10663:SF388; GOLGI-SPECIFIC BREFELDIN A-RESISTANCE GUANINE NUCLEOTIDE EXCHANGE FACTOR 1; 1.
DR PANTHER; PTHR10663; GUANYL-NUCLEOTIDE EXCHANGE FACTOR; 1.
DR Pfam; PF06229; FRG1; 1.
DR Pfam; PF01369; Sec7; 1.
DR Pfam; PF12783; Sec7-like_HUS; 1.
DR SMART; SM00222; Sec7; 1.
DR SUPFAM; SSF48371; ARM repeat; 2.
DR SUPFAM; SSF48425; Sec7 domain; 1.
DR PROSITE; PS50190; SEC7; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000055048}.
FT DOMAIN 761..951
FT /note="SEC7"
FT /evidence="ECO:0000259|PROSITE:PS50190"
FT REGION 357..425
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1398..1417
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1546..1578
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1695..1727
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1874..1917
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1949..1986
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 367..395
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1546..1572
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1893..1908
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1951..1986
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1986 AA; 217865 MW; 1559FA670C06F46D CRC64;
MALMGHNNCF MNYDNDAEGY IMVNSKKAKE NEMIKMRTNA ERAVVGDSVP EQDKKPSGEC
EVSYIKLYQH SKVKVSQEDR SNVKRAKVQG NLHEVLLDRN TLYIVQSELN AVVATLRRSQ
RLLGGVPQGQ DPLLRSFFDL REVLSSVPSL ADVAPSVFVA PFLDVIRSDH TGGTATEQAL
VSVDKFLSYG LFDPACITAA SAVQQIAEAV TRARFVGTDP SFDEVVILRI LQVLRALLLS
PAGALLTDET VCEMLQSCFR ICFEEGLSQL LRKAAESCLK DMVQLIFKRL ADFREDPRHP
YVRRLQTRAS SRDETFSSRR RLKRRRKHFA AVVSSEPSSL AAVEQAEHCP LGLDVLADAG
SGGSGSPPAS AGPSDQSGLQ ADGVVENSNT GNQPEIAVPA KLDPETLGTD DAGAAETVDP
SPSTGPYGLP CSRELFRFLI ALCNPWEQQQ NDQMIELGLN LLTVALEVGV DQLSKFSLML
PLVQNDLCRH LISLLQATKV SLLSSALRVG FLLFESLRCH LKLQLEMYLC KLMELATAAE
VLPTPTSATA QSGPSISSRT STLSNTVRLE LRELALEALV QLWRVPGLIT ELYLNYDCDL
YCSDLFEELT KLLSKNAFPV TGLTNAHILS LDALLTVVDT IELNCHLRMI NYRRHSSSSS
DAGGGDATAA AAAAATPCSF DGQWFQTATP SPGSRSSTAY ALPAVCGYSV GFAVSSGSLS
TTTGQQRSDD DVKLENETAP NPELLLCAVA AHETEIPSHE ELLRLKMKKQ ILTNASDLFN
QNPSKGIEFL QENGLLSMPY SPNEVVRWLR ENPRLNKRKI AEFIVNRKNR PVLDAFVKSF
DFRKLRIDES LREFLESFRL PGEAAEISTI IEYYADHWHK SNGTPFASTD AAFTLAYAVI
MLNVDQHNPQ AKRQQQPMSL EQFVKNLNGV NGGDNFDRTM LEKIYQAVRT EEIVMPEEQG
GLVRENYVWD VLLRRGAGTQ GRFLRAPGHG GGLYDRELFA LVWGPTVAAL SFVFDKTDSE
PLIGRVISGF RKSAAVAAHF GLCDVFDNLT ISLCKFSCLL TPARNADGAD QLCATLAESA
KAQAAARALF DLVHAHGDIL REGWRSVFDC LLNCYHAELL PLGLTDCEDF ADSRGYINIS
RPLPRAQKQD SSASGLLSSL YSYLGGSASG GDSRDADSHG ARQRNEWRQR GAALLVDCRV
DQTLVDSKYL SSQALSELVK ALLLASAAVL PDDGAVGRRR LSDVDERSLV FLTETMVSVA
VHNRDRIAPF WRTLHAHLFS LIADHADRRF LVERAVVGWL RLANRLLPRQ DVGDQVLDAL
PALGAASQAT VPSIARQLAH GLHQLLRANA AYVRLARHWD QLFALLELVG AGAFVGQLDS
TGDVRDQSFD QHRHQAFNTV GEQPKQQQQQ QQYDRGYTSD SELYTAAATT GSRKLPVGSV
GDLHSRAGSG EWTFVDKQQQ QQQQLDNGPT TPSKQLLSTR LLLRSGLRRH DPDAYVKCCE
TLTWLVRDAG HVSVENLQPC IRCVRTFVEA GLNGGLHYTN PITTANNNNN SATLSSTHQR
SSLSSGKDRN GTSQVNGEDK KKTLLDGCDL ASTYLQLSLQ LLDLTYLIFV KVATPLFDTP
TATLWTRCWQ PLLQALARLC CDRRRVVRTT AMTFLQRAML VPELKQITGQ DWESCFYWVL
FPLLSALLNA DQQSISNPST GTTPTTHHHH HNEDDNDDAA VAGGGGGCGG SMDETRVRAL
TMTSKVFLQH LMPLSTLDSF VDLWLDILDF MERYLELENN DLVESVPESV KNMLLVMHTA
GLFDTVPSLL DRTRHKLNAS FPDLAHAIDT QTSVVDQATA AAQPAPAHLA TANNNNNDDD
ISLEEVVVVA DPQPRAEAVP LPSTSTSPSK PLPLSSSQPP PLPSSLPPPQ QQQQQQQCSV
LLALNNNNNN NNTSAVPVTG QVILHPPVDI STVTPQPSSA VRNDHHHSAQ LTLDHNSTTD
DSTPVN
//
