ID   A0A0V0TL47_9BILA        Unreviewed;      1241 AA.
AC   A0A0V0TL47;
DT   16-MAR-2016, integrated into UniProtKB/TrEMBL.
DT   16-MAR-2016, sequence version 1.
DT   24-JAN-2024, entry version 20.
DE   SubName: Full=Regulator of nonsense transcripts 2 {ECO:0000313|EMBL:KRX39753.1};
DE   Flags: Fragment;
GN   Name=UPF2 {ECO:0000313|EMBL:KRX39753.1};
GN   ORFNames=T05_16071 {ECO:0000313|EMBL:KRX39753.1};
OS   Trichinella murrelli.
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Enoplea; Dorylaimia;
OC   Trichinellida; Trichinellidae; Trichinella.
OX   NCBI_TaxID=144512 {ECO:0000313|EMBL:KRX39753.1, ECO:0000313|Proteomes:UP000055048};
RN   [1] {ECO:0000313|EMBL:KRX39753.1, ECO:0000313|Proteomes:UP000055048}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ISS417 {ECO:0000313|EMBL:KRX39753.1};
RA   Korhonen P.K., Edoardo P., Giuseppe L.R., Gasser R.B.;
RT   "Evolution of Trichinella species and genotypes.";
RL   Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KRX39753.1}.
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DR   EMBL; JYDJ01000223; KRX39753.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A0V0TL47; -.
DR   Proteomes; UP000055048; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR   GO; GO:0000184; P:nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; IEA:InterPro.
DR   Gene3D; 1.25.40.180; -; 3.
DR   InterPro; IPR016024; ARM-type_fold.
DR   InterPro; IPR003890; MIF4G-like_typ-3.
DR   InterPro; IPR039762; Nmd2/UPF2.
DR   InterPro; IPR007193; Upf2/Nmd2_C.
DR   PANTHER; PTHR12839; NONSENSE-MEDIATED MRNA DECAY PROTEIN 2 UP-FRAMESHIFT SUPPRESSOR 2; 1.
DR   PANTHER; PTHR12839:SF7; REGULATOR OF NONSENSE TRANSCRIPTS 2; 1.
DR   Pfam; PF02854; MIF4G; 3.
DR   Pfam; PF04050; Upf2; 1.
DR   SMART; SM00543; MIF4G; 3.
DR   SUPFAM; SSF48371; ARM repeat; 3.
PE   4: Predicted;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW   Reference proteome {ECO:0000313|Proteomes:UP000055048}.
FT   DOMAIN          77..274
FT                   /note="MIF4G"
FT                   /evidence="ECO:0000259|SMART:SM00543"
FT   DOMAIN          498..691
FT                   /note="MIF4G"
FT                   /evidence="ECO:0000259|SMART:SM00543"
FT   DOMAIN          709..923
FT                   /note="MIF4G"
FT                   /evidence="ECO:0000259|SMART:SM00543"
FT   REGION          337..373
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          461..493
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          1014..1051
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          1192..1212
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          1222..1241
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          1014..1051
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COMPBIAS        347..362
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        464..492
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   NON_TER         1
FT                   /evidence="ECO:0000313|EMBL:KRX39753.1"
SQ   SEQUENCE   1241 AA;  143446 MW;  C73F4E145B537CBE CRC64;
     LGLDFQNDYF IEVDFMSTVE VKSLGSGVEP VTDDEILSSI QQSIDRLGRK REIRQANLTA
     VETRPDETFL RKLDSSLKKN TAFVKRLKTF TESQSANIIR DFRTLNLSRY VTEMVSSLCE
     AKLKNSDIIP LIEFCSLAHQ RYADFSGFLL DYFKRTFSSS DSKVATNMSK LRVDLRFLVE
     LLLHGILTEK EAAPVLLDAV TIITRLEKER KFTFLSTLVS FCRQCGEDLL GLLPRNFRTV
     AQQKKIDYHC SDLISEELRE KLMMKVKAYY NALIVHVSGL NGELLKMRQK NMRQMESKGE
     VHPAAVRNFE ELKSTLDKLI QSMNTLANWL DVDTPHLPDE ATLEESGESI QKSVVSKSSE
     ESQSESPFED EESRLFYTSL PQLKEMLPQI LFQDAQKNQE NFSSEKDMEA MRALEKEMSE
     QMKKQSQPLQ VDNELKMENQ NGVDQSSVSY TDVDGISEET NTAELEDECV KSENCKSVNN
     GEKSEEDHED SSNVSSSILQ MKSFIAKLPL LINRDMIDQA AIEYATHLNT KSNRRRLIKT
     LFEVHRSRLD LLPFYSRLIA ILDPVFPDIR NEICHLLISQ FRHHIRKKDQ VQIESKVKVC
     RYIGELVKFG IFPKSDALLC FKLLLMDFRH HNIEMACAIL DSSGYYLFHS SDSHLKMKFL
     LEQMKRRAET LYLDFRYQGM IMNAYYTCYP ESVQPVVESC DQVEVPIVFK YIWHLVSNRT
     VLKEVEFVLK EMQKIDWSDA NVVNYVVRIF SEPWLLRAQY FNCIASVLCG IAEFYPIVGV
     RVADNVLEIF RSSLESDSML NQQQRMSLCM YMGELYNYKL INTSAYFNSL YLLLTLNVES
     VEGADIPTPV EGLFRIRLAC AMLQLCGSYF SRGVGAQKMT CYLKYLQQYC LRQASRECWK
     NDESAVLKVK ALLKETIEGL RKHGFVIFST LEEANEAISA MEADCRTRME HLVKTRYCCN
     DSAMHEMYEL EEHLPDSGEL DVDVVRETSH GEEYDEEDSD SSTIEANDHY FAEEEEFDEE
     EDDFEVQEEE EEEEEEEDEE LEEEEEEDDD DMLEEFNKCA LGDEEFLNDS SFNVEYEKLV
     NNMIQQRINE QVKIPQFDTA PSQITKNNQI NIANAEIVQE PEDSVTSEQK VKFLLLTKNK
     SNRSVVKTIQ VPEGSDLAMN WKHREAAALK EKERMKRLTL NMTQRMQYED NADVSDANQS
     PHTNADTFLE SKKSSIGYQM KQTNTKEFPG NSREMNSNGW F
//