ID A0A0V0TZY2_9BILA Unreviewed; 506 AA.
AC A0A0V0TZY2;
DT 16-MAR-2016, integrated into UniProtKB/TrEMBL.
DT 16-MAR-2016, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE SubName: Full=Homeobox protein Nkx-2.2a {ECO:0000313|EMBL:KRX44533.1};
DE Flags: Fragment;
GN Name=nkx2.2a {ECO:0000313|EMBL:KRX44533.1};
GN ORFNames=T05_10000 {ECO:0000313|EMBL:KRX44533.1};
OS Trichinella murrelli.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Enoplea; Dorylaimia;
OC Trichinellida; Trichinellidae; Trichinella.
OX NCBI_TaxID=144512 {ECO:0000313|EMBL:KRX44533.1, ECO:0000313|Proteomes:UP000055048};
RN [1] {ECO:0000313|EMBL:KRX44533.1, ECO:0000313|Proteomes:UP000055048}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ISS417 {ECO:0000313|EMBL:KRX44533.1};
RA Korhonen P.K., Edoardo P., Giuseppe L.R., Gasser R.B.;
RT "Evolution of Trichinella species and genotypes.";
RL Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123,
CC ECO:0000256|PROSITE-ProRule:PRU00108, ECO:0000256|RuleBase:RU000682}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KRX44533.1}.
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DR EMBL; JYDJ01000094; KRX44533.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0V0TZY2; -.
DR STRING; 144512.A0A0V0TZY2; -.
DR Proteomes; UP000055048; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0000981; F:DNA-binding transcription factor activity, RNA polymerase II-specific; IEA:InterPro.
DR CDD; cd00086; homeodomain; 1.
DR Gene3D; 1.10.10.60; Homeodomain-like; 1.
DR InterPro; IPR009057; Homeobox-like_sf.
DR InterPro; IPR017970; Homeobox_CS.
DR InterPro; IPR001356; Homeobox_dom.
DR PANTHER; PTHR24340; HOMEOBOX PROTEIN NKX; 1.
DR PANTHER; PTHR24340:SF82; HOMEOBOX PROTEIN VND-RELATED; 1.
DR Pfam; PF00046; Homeodomain; 1.
DR SMART; SM00389; HOX; 1.
DR SUPFAM; SSF46689; Homeodomain-like; 1.
DR PROSITE; PS00027; HOMEOBOX_1; 1.
DR PROSITE; PS50071; HOMEOBOX_2; 1.
PE 4: Predicted;
KW Developmental protein {ECO:0000256|ARBA:ARBA00022473};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|PROSITE-
KW ProRule:PRU00108};
KW Homeobox {ECO:0000256|ARBA:ARBA00023155, ECO:0000256|PROSITE-
KW ProRule:PRU00108};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|PROSITE-
KW ProRule:PRU00108}; Reference proteome {ECO:0000313|Proteomes:UP000055048}.
FT DOMAIN 340..400
FT /note="Homeobox"
FT /evidence="ECO:0000259|PROSITE:PS50071"
FT DNA_BIND 342..401
FT /note="Homeobox"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00108"
FT REGION 44..78
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 116..164
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 276..347
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 116..145
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 276..317
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:KRX44533.1"
FT NON_TER 506
FT /evidence="ECO:0000313|EMBL:KRX44533.1"
SQ SEQUENCE 506 AA; 57613 MW; F8EABA7C240445CF CRC64;
LFIRREISYL KVAPRLMLTS TGDAQLTQPA ASAETLTSKL ESTEKVDQVV DDNKKQQKQD
QLEDCRPASQ ERLTEQRSKR TTCFSVKDIL QLPSQRRQLS SKNRFAVALM YHHPQPQQQQ
HNVSPFHNQH NQQQQQSQQV TLHQHHQQEQ QHHHQLNDLF SATPNTPIND CTHYSHHSVG
HEYTPTSFAK PSHFQYANGV QLHLRHAFDQ APTTGYCNGR MPVATSPSPW LQATFSVRYP
QQTPASAVQT DFYHYRHLSP SSLTDAYMLD QPFHQITADK STRSPIHRQA SAKLDSPNPD
SKQQNSANNI TTDEKHIQNG SELSDKPEPV TAKKQTTSST KKRKRRILFS KSQTVELERR
FRQQRYLSAP ERELLAQQIR LTPTQVKIWF QNHRYKTKKG IHDRTIGPSH LNNSLMSSRR
ISIPLLVHDG KPCTGTRKTL DSVSSLPNPM PLMGAAHFGP LAPDPVTPTP PMGLFAGTSA
THHHHQQQTP APVLGASHYY LQNGWW
//
