ID A0A0V0UCW0_9BILA Unreviewed; 637 AA.
AC A0A0V0UCW0;
DT 16-MAR-2016, integrated into UniProtKB/TrEMBL.
DT 16-MAR-2016, sequence version 1.
DT 08-NOV-2023, entry version 20.
DE RecName: Full=protein phosphatase methylesterase-1 {ECO:0000256|ARBA:ARBA00013111};
DE EC=3.1.1.89 {ECO:0000256|ARBA:ARBA00013111};
GN Name=PPME1 {ECO:0000313|EMBL:KRX49003.1};
GN ORFNames=T05_15061 {ECO:0000313|EMBL:KRX49003.1};
OS Trichinella murrelli.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Enoplea; Dorylaimia;
OC Trichinellida; Trichinellidae; Trichinella.
OX NCBI_TaxID=144512 {ECO:0000313|EMBL:KRX49003.1, ECO:0000313|Proteomes:UP000055048};
RN [1] {ECO:0000313|EMBL:KRX49003.1, ECO:0000313|Proteomes:UP000055048}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ISS417 {ECO:0000313|EMBL:KRX49003.1};
RA Korhonen P.K., Edoardo P., Giuseppe L.R., Gasser R.B.;
RT "Evolution of Trichinella species and genotypes.";
RL Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=[phosphatase 2A protein]-C-terminal L-leucine methyl ester +
CC H2O = [phosphatase 2A protein]-C-terminal L-leucine + H(+) +
CC methanol; Xref=Rhea:RHEA:48548, Rhea:RHEA-COMP:12134, Rhea:RHEA-
CC COMP:12135, ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:17790,
CC ChEBI:CHEBI:90516, ChEBI:CHEBI:90517; EC=3.1.1.89;
CC Evidence={ECO:0000256|ARBA:ARBA00000906};
CC -!- SIMILARITY: Belongs to the AB hydrolase superfamily.
CC {ECO:0000256|ARBA:ARBA00008645}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KRX49003.1}.
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DR EMBL; JYDJ01000021; KRX49003.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0V0UCW0; -.
DR STRING; 144512.A0A0V0UCW0; -.
DR Proteomes; UP000055048; Unassembled WGS sequence.
DR GO; GO:0051723; F:protein methylesterase activity; IEA:InterPro.
DR Gene3D; 3.40.50.1820; alpha/beta hydrolase; 1.
DR InterPro; IPR029058; AB_hydrolase.
DR InterPro; IPR000073; AB_hydrolase_1.
DR InterPro; IPR016812; PPase_methylesterase_euk.
DR PANTHER; PTHR14189:SF0; PROTEIN PHOSPHATASE METHYLESTERASE 1; 1.
DR PANTHER; PTHR14189; PROTEIN PHOSPHATASE METHYLESTERASE-1 RELATED; 1.
DR Pfam; PF12697; Abhydrolase_6; 1.
DR SUPFAM; SSF53474; alpha/beta-Hydrolases; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000055048}.
FT DOMAIN 314..604
FT /note="AB hydrolase-1"
FT /evidence="ECO:0000259|Pfam:PF12697"
FT REGION 41..61
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 637 AA; 71280 MW; 1F9AE9D20F1F0470 CRC64;
MDRRTTTLAG LISHAVDLSP ASFSSKNAFW VTVFDEARKN FSRSSPPQQI DASSSTSTRI
SLQPRAKTPW ANLPHLCANV REFHSAYTSS CNKPFRQSNQ SQRSSTVDTT TAPAAARAVH
LFLPNFKLGH SSQHILHEFA TSRAQFDQIE RPFVTYFVQH LYTPQSQNFT EHLTHFWRCE
KITVFTKYTT SRCVITINGT RQSPVHVLGN GYWAAKANFM CQKLQEISSV RSSRKTNIGL
CKVMASELEK SLHKRLLISS PPKSRANLKT SKRLNADRFQ PLEWNVYFDK KETVKISDKN
LFNVYIKGKD GPLLVFLHGG GCSALSWACL AVNSFIIVLK SSAPKYLSSL ITCTVFAIDL
RGHGETTTDD EYNLALEVMA DDVAAVLKTY FSQITAPVIL IGHSMGGAVA VEVAHSKNIP
SLAALIVVDV SEGSALQALK CMQNYLLSRP KQFNSLPMAI EWSKRSSYIR NLESARVSMP
GQVKKIQSVK ENLVKSDQHP IDRIDEEAAE LEEIPQTSDV ECPESTIYGW RIDLSKTEKY
WEGWYTGMSE KFLSISVPKL LLLANKDNMD TALTTAQMQG KFQMALLTEV GHSVHEDSPE
KTAEIFASFL LRQRLAETLN AEAKEKLFNA AVQMRTC
//
