ID   A0A0V0UIH9_9BILA        Unreviewed;      1417 AA.
AC   A0A0V0UIH9;
DT   16-MAR-2016, integrated into UniProtKB/TrEMBL.
DT   16-MAR-2016, sequence version 1.
DT   27-MAR-2024, entry version 21.
DE   RecName: Full=RNA-dependent RNA polymerase {ECO:0000256|RuleBase:RU363098};
DE            EC=2.7.7.48 {ECO:0000256|RuleBase:RU363098};
GN   Name=RDR1 {ECO:0000313|EMBL:KRX50765.1};
GN   ORFNames=T05_4153 {ECO:0000313|EMBL:KRX50765.1};
OS   Trichinella murrelli.
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Enoplea; Dorylaimia;
OC   Trichinellida; Trichinellidae; Trichinella.
OX   NCBI_TaxID=144512 {ECO:0000313|EMBL:KRX50765.1, ECO:0000313|Proteomes:UP000055048};
RN   [1] {ECO:0000313|EMBL:KRX50765.1, ECO:0000313|Proteomes:UP000055048}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ISS417 {ECO:0000313|EMBL:KRX50765.1};
RA   Korhonen P.K., Edoardo P., Giuseppe L.R., Gasser R.B.;
RT   "Evolution of Trichinella species and genotypes.";
RL   Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=a ribonucleoside 5'-triphosphate + RNA(n) = diphosphate +
CC         RNA(n+1); Xref=Rhea:RHEA:21248, Rhea:RHEA-COMP:14527, Rhea:RHEA-
CC         COMP:17342, ChEBI:CHEBI:33019, ChEBI:CHEBI:61557, ChEBI:CHEBI:140395;
CC         EC=2.7.7.48; Evidence={ECO:0000256|ARBA:ARBA00024517,
CC         ECO:0000256|RuleBase:RU363098};
CC   -!- SIMILARITY: Belongs to the RdRP family. {ECO:0000256|ARBA:ARBA00005762,
CC       ECO:0000256|RuleBase:RU363098}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KRX50765.1}.
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DR   EMBL; JYDJ01000003; KRX50765.1; -; Genomic_DNA.
DR   STRING; 144512.A0A0V0UIH9; -.
DR   Proteomes; UP000055048; Unassembled WGS sequence.
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0003968; F:RNA-dependent RNA polymerase activity; IEA:UniProtKB-KW.
DR   GO; GO:0031047; P:regulatory ncRNA-mediated gene silencing; IEA:UniProt.
DR   InterPro; IPR007855; RNA-dep_RNA_pol_euk-typ.
DR   PANTHER; PTHR23079; RNA-DEPENDENT RNA POLYMERASE; 1.
DR   PANTHER; PTHR23079:SF55; RNA-DIRECTED RNA POLYMERASE; 1.
DR   Pfam; PF05183; RdRP; 1.
PE   3: Inferred from homology;
KW   Nucleotidyltransferase {ECO:0000256|RuleBase:RU363098};
KW   Reference proteome {ECO:0000313|Proteomes:UP000055048};
KW   RNA-binding {ECO:0000256|ARBA:ARBA00022884, ECO:0000256|RuleBase:RU363098};
KW   RNA-directed RNA polymerase {ECO:0000256|ARBA:ARBA00022484,
KW   ECO:0000256|RuleBase:RU363098};
KW   Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000256|RuleBase:RU363098}.
SQ   SEQUENCE   1417 AA;  163084 MW;  3A134001C8BD60CF CRC64;
     MSDVSDYFGE FHASVYIAKE VSGNSGLFDK VKNFVSSVCK PLSLHFSIRP CLAQENPDLF
     TEKFHTSISS DWEDLEKYHE SVVEIIKTWC STIRGNLHEQ PLLELIQDAT FPFQLIPLHK
     YNLQGKLSFG FMLNFGIFTE HCVVDLSGSW TAKAIFEHDR RYFSITIFRQ FSKNCSLKLL
     ILYDSVSAIQ VDFNDGKADI YFTLRHPPLI FGLDGGGEQK NQQRRFVRLN KFFSCDMENF
     GKCKVIKMTK SVAKCIVFKK FFWKFLLRMK KRCWNAKIFF GAVQTISVDN LVREDFAKRE
     ISDWPFWCQY YWLALGSRHH SIVYQLTNHF FDEVSRCLTE NLRSIEVAFI QLLCIIDNNS
     QLIVNVRQRF RQVYDKQCSL TDNDYSIELD LAAPYVSVRK VVITPTRVLL SVPDKMMSNR
     ILRQFGSDLA LRVIFRDEAG TRILASKFSL TSLKQIVTKV MTTGLTIGPR LYQFLGWSNS
     QLRDHGCYFY ASTEEVNVEE IRRWMGDFSS IRSVPKLMSR MGQCFTQAFA ITAIPFNADS
     KEVLIETDIQ SSDSKFCFSD GIGRMSTKLA EEVAERLELW PVPSAFQIRY AGFKGMLCVD
     PRLDGDVKMV FRQSMHKFHT EGTHTLEIVK HSQPCEVNLN RPLIMILDQV AFKEGFPVNG
     RVQNRVMQLL DQQICELSQM LLFEDQAKSV LSATLSSEMN FEKLADAGFR FTEEPFFRNM
     LLACYKFKVK EKLFRMKIEI DPSLGRTMYG VMDELGLLHP GQVFIQCSAS ILRPGEDKRV
     ITGKVMVTKS PSVVPGDVRI LTAVDLEIYH YLNDVIVFPK IGYRPVTDQM AGSDLDGDEY
     AVIWDEELMF VNNYPAMLYE KVISSEIDGD ITSDKMVDFF LHYMCSDSIG RIAIAHLVAS
     DSYGIFDDVS NCIARKHSMA VDFPKSGVTP PKLENDEIPF KYPDYIPKCY NSLYMSKWLL
     GSLYRKVSML NSIAELSLAR KVTTSKSDPH LKIAGAQNFE EKARAIFQRY KSELHSLLDE
     YGIENEFQLI TGKITKMHNR LSDGEQDDFS YYNTEKILKV RLGMLQKKYK KLFVSQFSSV
     ASKEQLANCS EVQAAASAWY SVAYRDAEIS NRTALSFPWL VWEVLLDLKL KNCPSERMDP
     VVVNLQNSIQ AQRMNNEQLM EIIDRIFENS KMNFENRQHF ENVQRILYTL FNWCDSVGLF
     AKSGGSTEVV NVVGQLFVDF VVFFEKSIEN EMALLELNDS NTRSNGSISD RYCARVLLKF
     LEHCVNRRFD FSPHGQQFSK SPEANILYRS AFKQYHGMAV SGNFRGLFPG DGINEETDIL
     LSDVREMEPM MLSLSRETLT FLKVGAIVAM LKKWSKCEEV AFRSVNIERD HDDRFLISAY
     GTLQARRRLQ NILLSNHIEQ WFKSGECNYD VDEIAWL
//