ID A0A0V0URP2_9BILA Unreviewed; 1238 AA.
AC A0A0V0URP2;
DT 16-MAR-2016, integrated into UniProtKB/TrEMBL.
DT 16-MAR-2016, sequence version 1.
DT 24-JAN-2024, entry version 24.
DE SubName: Full=Vacuolar protein sorting-associated protein VTA1-like protein {ECO:0000313|EMBL:KRX53874.1};
DE Flags: Fragment;
GN Name=ralbp1-a {ECO:0000313|EMBL:KRX53874.1};
GN ORFNames=T09_5991 {ECO:0000313|EMBL:KRX53874.1};
OS Trichinella sp. T9.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Enoplea; Dorylaimia;
OC Trichinellida; Trichinellidae; Trichinella.
OX NCBI_TaxID=181606 {ECO:0000313|EMBL:KRX53874.1, ECO:0000313|Proteomes:UP000054681};
RN [1] {ECO:0000313|EMBL:KRX53874.1, ECO:0000313|Proteomes:UP000054681}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ISS409 {ECO:0000313|EMBL:KRX53874.1};
RA Korhonen P.K., Edoardo P., Giuseppe L.R., Gasser R.B.;
RT "Evolution of Trichinella species and genotypes.";
RL Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KRX53874.1}.
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DR EMBL; JYDN01000188; KRX53874.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0V0URP2; -.
DR Proteomes; UP000054681; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.
DR GO; GO:0031267; F:small GTPase binding; IEA:InterPro.
DR GO; GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
DR CDD; cd00159; RhoGAP; 1.
DR Gene3D; 1.20.58.90; -; 1.
DR Gene3D; 1.10.555.10; Rho GTPase activation protein; 1.
DR Gene3D; 1.25.40.270; Vacuolar protein sorting-associated protein vta1; 1.
DR InterPro; IPR039767; RALBP1.
DR InterPro; IPR049041; RalBP1-like_Ral-bd.
DR InterPro; IPR008936; Rho_GTPase_activation_prot.
DR InterPro; IPR000198; RhoGAP_dom.
DR InterPro; IPR039431; Vta1/CALS_N.
DR InterPro; IPR023175; Vta1/CALS_N_sf.
DR PANTHER; PTHR12783; RALA BINDING PROTEIN 1 RALBP1; 1.
DR PANTHER; PTHR12783:SF5; RALA-BINDING PROTEIN 1; 1.
DR Pfam; PF00620; RhoGAP; 1.
DR Pfam; PF20924; RLIP76_Ral-bd; 1.
DR Pfam; PF04652; Vta1; 1.
DR SMART; SM00324; RhoGAP; 1.
DR SUPFAM; SSF48350; GTPase activation domain, GAP; 1.
DR PROSITE; PS50238; RHOGAP; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW GTPase activation {ECO:0000256|ARBA:ARBA00022468};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000054681};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 297..317
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 453..644
FT /note="Rho-GAP"
FT /evidence="ECO:0000259|PROSITE:PS50238"
FT REGION 408..439
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 1054..1129
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 408..436
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1238
FT /evidence="ECO:0000313|EMBL:KRX53874.1"
SQ SEQUENCE 1238 AA; 141568 MW; FD281B7B9F7F1F77 CRC64;
MRSFRVPSVP VPEFRLRWLT MTDGKTSMRE LPVSYGSLSP FLKLAAKFRS YNIIGEYWCL
KYVLQRLYRM KIYSKECLDF AFSLMSYVEQ LRLEFPLIIP LADKRSAAPF VLCEATRMFE
RADTFDRHAR YSVSLVQLYM QASNLFTVLS MLCELDDIAI KIQKYCKWRA WYLFNCFKNG
ETPLPAPKSV MLHLDSFQSD EERLQCPWKH EEIIPLGVKI GLPIQFWNFF SECEEHCVFF
DMLVERFGHF NVVYKLCKSA MHALENDNEE DVIDKLERAL RLAILIKCGI KACCVVFFEY
VIRFVVILFI SIFLNFATDM NKVIRFIWED RFMEDATVCF GSKDAVLSLS HSDLDEGSSE
SLYQCDEWTS KKGKREKKDK GYCYLHRLSS EEQLVHIRPK PKKTVFGKLK DKNKEKDKEK
EKEQKSKSKS KQKCKNKAET VAPAAPARPV FAVPLARALC NNPSYDRVPV PAFVRRCIDY
INENALDQEG LYRVSPSVEE LRNAVDNGEE PSFGDAYQAA CLLKLFIREL PESLFTEELL
DKFEHAAQSR AQQDDHSENV FHIATAFQRV AAVVECFSAE SANFVSECFT EKVTDQPSQT
GVALPGIEGE VDEAQVELLE TVGRAERVRV EQVQVRVAQG SRLYRQQSRA GQVEQFELVQ
AGQSVRFDQH QLAVVVQMQR SQRAERGEGV VGDVGELVPS QIQRVEFGQA GELVAVDVGD
VVAGQIELAQ ASHGGERVRL DRRDQVDAQV EHFESRQTVE HRTGQVFQKI PRQIQLDQLS
ERSEGVAGQR GDGIFLHAQL AQVGQRRSDH GQRPVVETVA GAQDQRVDHR QVVERARLEA
LQAVVGQVDR AQVFQVGQRP GSERSNRIVG QFEHFEPLEL ADHGWHVVQP AAEYGQLAQG
MRDACERAVR EVEPLPCAAA EYCQFFGCDV VGLEVAVRHA VAEEVHFAQL DTPNVGSGPA
HLVHRFGQRI DGRTEQTVNH RPLLLIFCRH RVAVAVFSGV HWTYISPLRP ASGKSLPTDP
KAILEELAKQ EFLLSHLHDE INSGINDPQK EEQLWDVQRL VTQLKRELKS LKKKNIDAFN
EVEQESGPCI EMFEEKQLLA VHMDLRNKIE IQRAQIEELM RQMDDIGGQH AVLSARSVAR
FSDAELSPEK KFDPKWPEQY SALEDRKREL IESIFAVDTL HCKQYTTYNY TECIYCHSHY
YYYYGYITTT VAKIQASSCT ILEHTILITL QFSFCNFD
//
