ID A0A0V0URW6_9BILA Unreviewed; 698 AA.
AC A0A0V0URW6;
DT 16-MAR-2016, integrated into UniProtKB/TrEMBL.
DT 16-MAR-2016, sequence version 1.
DT 27-MAR-2024, entry version 35.
DE SubName: Full=TBC1 domain family member 13 {ECO:0000313|EMBL:KRX53719.1};
GN ORFNames=T09_15191 {ECO:0000313|EMBL:KRX53719.1};
OS Trichinella sp. T9.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Enoplea; Dorylaimia;
OC Trichinellida; Trichinellidae; Trichinella.
OX NCBI_TaxID=181606 {ECO:0000313|EMBL:KRX53719.1, ECO:0000313|Proteomes:UP000054681};
RN [1] {ECO:0000313|EMBL:KRX53719.1, ECO:0000313|Proteomes:UP000054681}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ISS409 {ECO:0000313|EMBL:KRX53719.1};
RA Korhonen P.K., Edoardo P., Giuseppe L.R., Gasser R.B.;
RT "Evolution of Trichinella species and genotypes.";
RL Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123,
CC ECO:0000256|PROSITE-ProRule:PRU00108, ECO:0000256|RuleBase:RU000682}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KRX53719.1}.
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DR EMBL; JYDN01000193; KRX53719.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0V0URW6; -.
DR Proteomes; UP000054681; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0030182; P:neuron differentiation; IEA:UniProt.
DR CDD; cd00086; homeodomain; 1.
DR CDD; cd09379; LIM2_AWH; 1.
DR Gene3D; 2.10.110.10; Cysteine Rich Protein; 2.
DR Gene3D; 1.10.10.60; Homeodomain-like; 1.
DR Gene3D; 1.10.8.270; putative rabgap domain of human tbc1 domain family member 14 like domains; 1.
DR Gene3D; 1.10.472.80; Ypt/Rab-GAP domain of gyp1p, domain 3; 1.
DR InterPro; IPR009057; Homeobox-like_sf.
DR InterPro; IPR001356; Homeobox_dom.
DR InterPro; IPR000195; Rab-GAP-TBC_dom.
DR InterPro; IPR035969; Rab-GAP_TBC_sf.
DR InterPro; IPR001781; Znf_LIM.
DR PANTHER; PTHR24208; LIM/HOMEOBOX PROTEIN LHX; 1.
DR PANTHER; PTHR24208:SF127; LIM_HOMEOBOX PROTEIN AWH; 1.
DR Pfam; PF00046; Homeodomain; 1.
DR Pfam; PF00412; LIM; 2.
DR Pfam; PF00566; RabGAP-TBC; 1.
DR SMART; SM00389; HOX; 1.
DR SMART; SM00132; LIM; 2.
DR SMART; SM00164; TBC; 1.
DR SUPFAM; SSF57716; Glucocorticoid receptor-like (DNA-binding domain); 2.
DR SUPFAM; SSF46689; Homeodomain-like; 1.
DR SUPFAM; SSF47923; Ypt/Rab-GAP domain of gyp1p; 2.
DR PROSITE; PS50071; HOMEOBOX_2; 1.
DR PROSITE; PS00478; LIM_DOMAIN_1; 1.
DR PROSITE; PS50023; LIM_DOMAIN_2; 2.
DR PROSITE; PS50086; TBC_RABGAP; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|PROSITE-ProRule:PRU00108,
KW ECO:0000256|RuleBase:RU000682};
KW Homeobox {ECO:0000256|PROSITE-ProRule:PRU00108,
KW ECO:0000256|RuleBase:RU000682};
KW LIM domain {ECO:0000256|ARBA:ARBA00023038, ECO:0000256|PROSITE-
KW ProRule:PRU00125}; Metal-binding {ECO:0000256|PROSITE-ProRule:PRU00125};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|PROSITE-
KW ProRule:PRU00108}; Reference proteome {ECO:0000313|Proteomes:UP000054681};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Zinc {ECO:0000256|PROSITE-ProRule:PRU00125}.
FT DOMAIN 34..332
FT /note="Rab-GAP TBC"
FT /evidence="ECO:0000259|PROSITE:PS50086"
FT DOMAIN 417..478
FT /note="LIM zinc-binding"
FT /evidence="ECO:0000259|PROSITE:PS50023"
FT DOMAIN 479..540
FT /note="LIM zinc-binding"
FT /evidence="ECO:0000259|PROSITE:PS50023"
FT DOMAIN 549..609
FT /note="Homeobox"
FT /evidence="ECO:0000259|PROSITE:PS50071"
FT DNA_BIND 551..610
FT /note="Homeobox"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00108"
FT REGION 605..658
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 698 AA; 80940 MW; 94C05F4CAB18DD29 CRC64;
MVNNRRRIEC FRQILDQDRI DLKLLREACF CGIPDESELR PICWRLLLNY LPIEKVKWPE
YLKNQRKLYA DLVEDIVIKW NSILDTDEHS CDHPLSAEPN SVWSQYFRDN EVLVQINKDV
RRLCPEMSFF QKITQYPCQA IVKNGALALS QRVLTSTLRA EHLRNHRSGA NNLVEDCSKR
GNDDYFTIDK GKETHWQVVE RILFIYSKLN PGVKYVQGMN EIVGPIYFVF ASDSQWQEHA
EADTFFCFQN LMSEIKDNFI KTLDSSNVGI DHQMRALYSL LQRVDPVLHQ AMTEVQQLCP
QYFAFRWLSL LLSQEFLLPD VIRLWDTLFA DCRRFEFLLY VCLAMLILVR NDILTNEFSV
NVRMLQNYPP IDIVSVIKLA SEIRAVMEDR HPCVQGKLNL PLPESKAMKS DVYLTEEICS
GCGNLIYDRY LLQVNQQLWH VNCLRCSSCT ALLDKLPSCY LKEDKVFCKM CYQRQFSVKC
DRCNQVIQSN HWVRRARQYV YHLACFACDS CQRQLSTGEE FALQDSRVLC KQHYMELLEG
DNGKVHHKQK TKRVRTTFTE EQLQILQANF QIDSNPDGQD LERIAQGTGL SKRVTQVWFQ
NSRARQKKCQ GVKAKSNSSH PNQSSQDSYD ESSPSGPVSE PVTSHSIRSS PSQEDFSDLQ
YITDANEANV SMETDHIHMN AMFDSIDSVS SSVTNSPC
//
