ID   A0A0V0USD5_9BILA        Unreviewed;       518 AA.
AC   A0A0V0USD5;
DT   16-MAR-2016, integrated into UniProtKB/TrEMBL.
DT   16-MAR-2016, sequence version 1.
DT   22-FEB-2023, entry version 17.
DE   RecName: Full=Transcription initiation factor IIF subunit alpha {ECO:0000256|RuleBase:RU366044};
GN   ORFNames=T09_11093 {ECO:0000313|EMBL:KRX54005.1};
OS   Trichinella sp. T9.
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Enoplea; Dorylaimia;
OC   Trichinellida; Trichinellidae; Trichinella.
OX   NCBI_TaxID=181606 {ECO:0000313|EMBL:KRX54005.1, ECO:0000313|Proteomes:UP000054681};
RN   [1] {ECO:0000313|EMBL:KRX54005.1, ECO:0000313|Proteomes:UP000054681}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ISS409 {ECO:0000313|EMBL:KRX54005.1};
RA   Korhonen P.K., Edoardo P., Giuseppe L.R., Gasser R.B.;
RT   "Evolution of Trichinella species and genotypes.";
RL   Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: TFIIF is a general transcription initiation factor that binds
CC       to RNA polymerase II and helps to recruit it to the initiation complex
CC       in collaboration with TFIIB. It promotes transcription elongation.
CC       {ECO:0000256|ARBA:ARBA00025232, ECO:0000256|RuleBase:RU366044}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123,
CC       ECO:0000256|RuleBase:RU366044}.
CC   -!- SIMILARITY: Belongs to the TFIIF alpha subunit family.
CC       {ECO:0000256|ARBA:ARBA00005249, ECO:0000256|RuleBase:RU366044}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KRX54005.1}.
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DR   EMBL; JYDN01000183; KRX54005.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A0V0USD5; -.
DR   Proteomes; UP000054681; Unassembled WGS sequence.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0032968; P:positive regulation of transcription elongation by RNA polymerase II; IEA:InterPro.
DR   GO; GO:0006367; P:transcription initiation at RNA polymerase II promoter; IEA:InterPro.
DR   Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR   InterPro; IPR008851; TFIIF-alpha.
DR   InterPro; IPR011039; TFIIF_interaction.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   PANTHER; PTHR13011:SF0; GENERAL TRANSCRIPTION FACTOR IIF SUBUNIT 1; 1.
DR   PANTHER; PTHR13011; TFIIF-ALPHA; 1.
DR   Pfam; PF05793; TFIIF_alpha; 1.
DR   SUPFAM; SSF50916; Rap30/74 interaction domains; 1.
PE   3: Inferred from homology;
KW   DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|RuleBase:RU366044};
KW   Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|RuleBase:RU366044};
KW   Reference proteome {ECO:0000313|Proteomes:UP000054681};
KW   Transcription {ECO:0000256|ARBA:ARBA00023163,
KW   ECO:0000256|RuleBase:RU366044};
KW   Transcription regulation {ECO:0000256|ARBA:ARBA00023015,
KW   ECO:0000256|RuleBase:RU366044}.
FT   REGION          1..21
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          181..247
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          269..290
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          356..377
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        181..222
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        223..238
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        356..372
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   518 AA;  59550 MW;  E44FAF6B552A3D63 CRC64;
     MYNLQNQRKQ PGPGTNHQYD RQLSVKKVPI KLKQMKLRIV GLEKEAGQKV REARAGQKQF
     GIEAEFSYLF LPTLSTSVPD SKNCNMQASK EHLPLRLAVE ANCKVRHYRG IRDGVISNYS
     DYWIFEKNGK NAFDAYLVGE IYNLIPVRDR KAMSIEEVEE HFKRRREIVL NQFALRARIR
     RPGEENDNDD ESESARGHQN EKCEKGAYKT ETDKRNDHED GVVMEESDDG DEDGREVDCM
     SDGDCSSGVE LEEKTLVGID EELTDAFQSV DESEQDDENA ENDKQGGPIK LEDMNKKKLL
     QRLQILGCER NEICHIFQNN YNCNSEDFDS EDIKSLFLLQ CKTDVKPVSS KRKVELDSLA
     EQKPKKKAKL PNAGTDSDGS KFRIMEEEVR HCFQRHPMST TDLVAKKSKP EQTRRKGTLH
     FTLLYVAHKA LEIDENSLLY PMVKRYCIRS ISKCEAKKIF FHHYSTINLI ISKTPQTSLS
     YDAVKFAQIY EETIPLFFCF QTKNVGMHLK RALSGCVS
//