ID A0A0V0USS1_9BILA Unreviewed; 551 AA.
AC A0A0V0USS1;
DT 16-MAR-2016, integrated into UniProtKB/TrEMBL.
DT 16-MAR-2016, sequence version 1.
DT 24-JAN-2024, entry version 20.
DE RecName: Full=Protein tweety homolog {ECO:0000256|RuleBase:RU361114};
GN ORFNames=T09_14398 {ECO:0000313|EMBL:KRX54149.1};
OS Trichinella sp. T9.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Enoplea; Dorylaimia;
OC Trichinellida; Trichinellidae; Trichinella.
OX NCBI_TaxID=181606 {ECO:0000313|EMBL:KRX54149.1, ECO:0000313|Proteomes:UP000054681};
RN [1] {ECO:0000313|EMBL:KRX54149.1, ECO:0000313|Proteomes:UP000054681}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ISS409 {ECO:0000313|EMBL:KRX54149.1};
RA Korhonen P.K., Edoardo P., Giuseppe L.R., Gasser R.B.;
RT "Evolution of Trichinella species and genotypes.";
RL Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Probable chloride channel. {ECO:0000256|RuleBase:RU361114}.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|RuleBase:RU361114};
CC Multi-pass membrane protein {ECO:0000256|RuleBase:RU361114}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the tweety family.
CC {ECO:0000256|ARBA:ARBA00009849, ECO:0000256|RuleBase:RU361114}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KRX54149.1}.
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DR EMBL; JYDN01000180; KRX54149.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0V0USS1; -.
DR Proteomes; UP000054681; Unassembled WGS sequence.
DR GO; GO:0034707; C:chloride channel complex; IEA:UniProtKB-UniRule.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005254; F:chloride channel activity; IEA:UniProtKB-UniRule.
DR InterPro; IPR006990; Tweety.
DR PANTHER; PTHR12424:SF8; PROTEIN TWEETY; 1.
DR PANTHER; PTHR12424; TWEETY-RELATED; 1.
DR Pfam; PF04906; Tweety; 1.
PE 3: Inferred from homology;
KW Chloride {ECO:0000256|RuleBase:RU361114};
KW Chloride channel {ECO:0000256|RuleBase:RU361114};
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Ion channel {ECO:0000256|RuleBase:RU361114};
KW Ion transport {ECO:0000256|RuleBase:RU361114};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU361114};
KW Reference proteome {ECO:0000313|Proteomes:UP000054681};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU361114};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|RuleBase:RU361114};
KW Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|RuleBase:RU361114}.
FT TRANSMEM 90..114
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU361114"
FT TRANSMEM 241..260
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU361114"
FT TRANSMEM 272..303
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU361114"
FT TRANSMEM 424..443
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU361114"
FT TRANSMEM 489..510
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU361114"
SQ SEQUENCE 551 AA; 63211 MW; 9677D6BB4B663F11 CRC64;
MKYFYRRCWI YERKQRHIYY EITEKITYVK QNIILTASIT IVQPRFDIDR KTGVMLWLAE
LFHKFPKVNF AFHSVESKFD LTNKDYVEAL IIYATCPVIL CVLLFIVIIG VWSVKCCTKG
NTSKPKSDAR AIASGLIACL GVSMNEVVYG IGDLGNELTK FGEKVQLYNF SLNSELLPAM
RTLQNELQDA KVLLNDQFWK NFSMMIEVGV HEMDSLVQFG SDLTTLENSK YFIQRLEFER
WMLCVILFAI VLIVNLWGLI GSCNLSGKGI MFFSGAGIIT FLVVWALVAF AFVLCLAVSD
FCLDPYPSLE RFMNDDFSLM LRYFRKCVEN KDSVLEGTPL GRLLQQTKDM HIFLTRFFMN
LKLEGKETSH PEIWTAISGI HDAYAEATKS AVSLYNLVSC SNMREEYKTI RYGLCNESLS
ANSVLLMALT AFGIIQFVTL LIVSSSWKAF QPRADAAAVH TDFYGSHVFN PLCVHVIDFH
LRCQQNAQVL FRLLMYVVYK LVPLLLQLII ADKFPSFRVS FKLLAFMNFI ERKIKNCTAM
HFTTCASFER I
//
