ID A0A0V0V6P6_9BILA Unreviewed; 934 AA.
AC A0A0V0V6P6;
DT 16-MAR-2016, integrated into UniProtKB/TrEMBL.
DT 16-MAR-2016, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE RecName: Full=Ceramide transfer protein {ECO:0000256|ARBA:ARBA00021440};
DE AltName: Full=Collagen type IV alpha-3-binding protein {ECO:0000256|ARBA:ARBA00031527};
GN ORFNames=T09_8407 {ECO:0000313|EMBL:KRX59160.1};
OS Trichinella sp. T9.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Enoplea; Dorylaimia;
OC Trichinellida; Trichinellidae; Trichinella.
OX NCBI_TaxID=181606 {ECO:0000313|EMBL:KRX59160.1, ECO:0000313|Proteomes:UP000054681};
RN [1] {ECO:0000313|EMBL:KRX59160.1, ECO:0000313|Proteomes:UP000054681}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ISS409 {ECO:0000313|EMBL:KRX59160.1};
RA Korhonen P.K., Edoardo P., Giuseppe L.R., Gasser R.B.;
RT "Evolution of Trichinella species and genotypes.";
RL Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=N-hexadecanoylsphing-4-enine(in) = N-hexadecanoylsphing-4-
CC enine(out); Xref=Rhea:RHEA:45720, ChEBI:CHEBI:72959;
CC Evidence={ECO:0000256|ARBA:ARBA00000074};
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC Endoplasmic reticulum {ECO:0000256|ARBA:ARBA00004240}. Golgi apparatus
CC {ECO:0000256|ARBA:ARBA00004555}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KRX59160.1}.
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DR EMBL; JYDN01000076; KRX59160.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0V0V6P6; -.
DR Proteomes; UP000054681; Unassembled WGS sequence.
DR GO; GO:0005581; C:collagen trimer; IEA:UniProtKB-KW.
DR GO; GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-SubCell.
DR GO; GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0008289; F:lipid binding; IEA:InterPro.
DR CDD; cd13283; PH_GPBP; 1.
DR CDD; cd08872; START_STARD11-like; 1.
DR Gene3D; 3.30.530.20; -; 1.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR InterPro; IPR010876; C1orf43.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR001849; PH_domain.
DR InterPro; IPR041952; STARD11_START.
DR InterPro; IPR023393; START-like_dom_sf.
DR InterPro; IPR002913; START_lipid-bd_dom.
DR PANTHER; PTHR19308:SF53; CERAMIDE TRANSFER PROTEIN; 1.
DR PANTHER; PTHR19308; PHOSPHATIDYLCHOLINE TRANSFER PROTEIN; 1.
DR Pfam; PF07406; NICE-3; 1.
DR Pfam; PF00169; PH; 1.
DR Pfam; PF01852; START; 1.
DR SMART; SM00233; PH; 1.
DR SMART; SM00234; START; 1.
DR SUPFAM; SSF55961; Bet v1-like; 1.
DR SUPFAM; SSF50729; PH domain-like; 1.
DR PROSITE; PS50003; PH_DOMAIN; 1.
DR PROSITE; PS50848; START; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW Collagen {ECO:0000313|EMBL:KRX59160.1};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Endoplasmic reticulum {ECO:0000256|ARBA:ARBA00022824};
KW Golgi apparatus {ECO:0000256|ARBA:ARBA00023034};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000054681};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 22..45
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 339..433
FT /note="PH"
FT /evidence="ECO:0000259|PROSITE:PS50003"
FT DOMAIN 726..928
FT /note="START"
FT /evidence="ECO:0000259|PROSITE:PS50848"
FT REGION 239..263
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 599..626
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 934 AA; 105973 MW; 0B304EABE6A39252 CRC64;
MEYANISNAG NNSTSGYRLG QISGITLTYL IALAGQILAV VFIMAKRRVV RNNLLLPKNP
YSAAGTGASA RFRAKIQRGI LLTSSYKHFH PLLVGGSEQE RAERFRRQAV DSFATVLTKL
GSWARFRWSR HSLPTVALLR RLVDEGYIGG QQQVTDDDCE QFASLYDTAR YTSRPFGEQE
LDRFVLLYEK MFAGVEGWHE KQPLEEDVRM YHITSLGTQS LNLAKRTIKR ALSSHQQSDS
VVVTTSQQQQ QQQQHQQQQS TGAAEPLLVE HQHPPARRAQ PQQQENWICG NCASSPTQHK
LCADGFFQTT SSASRNDDNS NCAETVSWSS EGEPVESACP ILTGVLNKWT NYIHGWQPRY
FVLQAGTLAY YKSEQEIEFG CRGAITVSKA IIQMHDYDDC RVDISVNDCV WYLRADRLQD
RQRWLDAIEA YRADSGYGSQ GDLCRHGSLV SLTSNKSLAS SSSFKVCQGL NEKISELETY
REIVLRQIDT LQSYFDSCAE ETTSTWNIPR APREPGEDFD DVDADHTMVH PSPHLITMGT
AGILNAHANG TTVHHREEPT IPNAKRAADF RSEALTFKAT TAGILPLLQH CTDLVQQSED
AWKRRLEQET DRRKRADDNC RQLALELQKL HVDRSSLAFG GPDYEEGPHS ALKEDEWHDA
LDAALEKQDL EDRRVERLLA RNVGPGKLQP FDKILLSTDH ALFNEIEQTT MEQVKYAQQG
VSDGEWQLFS EDGEMKMYRR EVEIGGLVCD PLKAVHHVKG VSALEYLHYF YEPDYKMDWD
TTLEELKVIE RMSEDTMILQ QIHKRVWPAA QRESLFWSHI RRVPKPTDSN ALDMIVVCNH
DTQHAAAPPN SRTVRVGLTI AMVCQTIVEN ASVDRNKLTR DDVSCKITYV AQVNPRGWAP
SSVLRAVYKR EYPKFLKRFT QYVLQKVENS PIQL
//
