ID A0A0V0V6X0_9BILA Unreviewed; 1334 AA.
AC A0A0V0V6X0;
DT 16-MAR-2016, integrated into UniProtKB/TrEMBL.
DT 16-MAR-2016, sequence version 1.
DT 27-MAR-2024, entry version 35.
DE SubName: Full=Protein HIRA {ECO:0000313|EMBL:KRX59224.1};
DE Flags: Fragment;
GN ORFNames=T09_4479 {ECO:0000313|EMBL:KRX59224.1};
OS Trichinella sp. T9.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Enoplea; Dorylaimia;
OC Trichinellida; Trichinellidae; Trichinella.
OX NCBI_TaxID=181606 {ECO:0000313|EMBL:KRX59224.1, ECO:0000313|Proteomes:UP000054681};
RN [1] {ECO:0000313|EMBL:KRX59224.1, ECO:0000313|Proteomes:UP000054681}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ISS409 {ECO:0000313|EMBL:KRX59224.1};
RA Korhonen P.K., Edoardo P., Giuseppe L.R., Gasser R.B.;
RT "Evolution of Trichinella species and genotypes.";
RL Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the WD repeat HIR1 family.
CC {ECO:0000256|ARBA:ARBA00007306}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KRX59224.1}.
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DR EMBL; JYDN01000075; KRX59224.1; -; Genomic_DNA.
DR Proteomes; UP000054681; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:InterPro.
DR GO; GO:0006338; P:chromatin remodeling; IEA:InterPro.
DR GO; GO:0006351; P:DNA-templated transcription; IEA:InterPro.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd00200; WD40; 1.
DR Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 2.
DR InterPro; IPR031120; HIR1-like.
DR InterPro; IPR011494; HIRA-like_C.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR InterPro; IPR036322; WD40_repeat_dom_sf.
DR InterPro; IPR001680; WD40_rpt.
DR PANTHER; PTHR13831; MEMBER OF THE HIR1 FAMILY OF WD-REPEAT PROTEINS; 1.
DR PANTHER; PTHR13831:SF0; PROTEIN HIRA; 1.
DR Pfam; PF07569; Hira; 1.
DR Pfam; PF00400; WD40; 3.
DR SMART; SM00320; WD40; 6.
DR SUPFAM; SSF50978; WD40 repeat-like; 2.
DR PROSITE; PS50082; WD_REPEATS_2; 3.
DR PROSITE; PS50294; WD_REPEATS_REGION; 3.
PE 3: Inferred from homology;
KW Chromatin regulator {ECO:0000256|ARBA:ARBA00022853};
KW Reference proteome {ECO:0000313|Proteomes:UP000054681};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015};
KW WD repeat {ECO:0000256|ARBA:ARBA00022574, ECO:0000256|PROSITE-
KW ProRule:PRU00221}.
FT REPEAT 69..100
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 125..157
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 168..200
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT DOMAIN 738..933
FT /note="Protein HIRA-like C-terminal"
FT /evidence="ECO:0000259|Pfam:PF07569"
FT REGION 529..560
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 578..615
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 596..615
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:KRX59224.1"
SQ SEQUENCE 1334 AA; 148623 MW; 731B39D5889EDBD1 CRC64;
LEMKFIKPNW VNHDGLPIYS VDIEPAGNRF ATGGQSVTGI GLIVLWSLKP VIDVENETND
KIPLLLCRLE AHSTCINCIR WSSDSRYLAS AGTDQAVKIW RFVSYIPNVQ SRVTAVEHWK
CVSTLHGHAG DVLHLSWSPG DRYLASCGID NIIIIWNAKK FPEKITSLVG HEGFVKGVCW
DPIGKYLASQ SDDRSLRIWS TVDWNVVHKF RRPFKEAPCA THTLRLDWSP DGLLLATAHA
VNNGGPVSKI IERNGWKCEL DFAGHRMAIT CVRWSNVLYH RNRKVFLTEK SNVCSCCAIG
SKDRSLSVWS ASENRPVVVL TDIFESSISD ISWDSSGLIL IAASVDGSVV CLVWTTDELG
VPLSLDEKIN NLRRYYGNVD VGLLGLQRKS DQNSNKIIED ADYVMTHAKV IANRSNENGV
NGGVCASTTA VRTAPPPSTS DSNWNVQLET RTKSGKRRIT PINVEVVAEV DTDNNSQPPW
IREGVGLGVA GKAKGLIDEK MTVIDNAERW SGLNSTTVEP LVAPSFSSAS ASKSTLVKSR
KGDNFDAGGK SISKSSEDHS GGIVEEFLEK SKSELKFDKK KSWHQKGKKA SKHAPRESPI
SQTFPSSETE VEVETDFQTH QTVAVSSSSK QKTPTHRLEA LKVVQLLMSS VVVDEVIRTG
RDREGVLIGS ESEVLLQLSN NIGSKPKGKF AELLCMKNSN CVWKVLLETG AVALKANRHL
ILVVFENGMF DILSPLDGRM MCLTNVLGDS VHYVNLDGKL IALVTVCAEL YVWSFVKSLE
LVCQVSLKAL LRDPKLNLSR IVFSAVGMPI ISFNDGSLFS YDASSKIWQK LLNPSDSFIK
YSPTSMLAST KAYLKTKGRF QNLCKNLFSS VTFTAERDSE MQERIREGFL ERFSLASRAV
GSEHEYMYWL SEYVKLLVKA ESEVKLRCLF RTLVESDEHM KTNSMLSRDK SEKRSAVTDL
LPLVAANPKL QRLYSELSFL VAEKSSNEQA DDLYSEIAAT RVGCNLLAKY YTTNSLKLSC
DVMSVEKFMK SASEEKSSHM SMAVILLNKM NKRCVGYVLK SDKDSSSGSR FILTTRTCSA
NFNRQINAPI YILPENKERH VKAIHTRGFH ESLAVIEMQD KYAFKLASES TCPLEFPEIS
EECFTVYAVE SQVNKRDIVA EPYKSSPKSS CEKYWITFNE ESFACAATSQ KEKRNGLGLV
CSQGGKLALV GISSENQQTT SVTSFTLLYP YAKQTGKCFH RINKIFQFLE NVMQRFATKN
EIAQFTFLKF NTVILELLGK NSFLKCSREN SQWKSIDQQY GSDSQSGGNL HRLQRGKISD
GFQGDSFFAF VNSE
//
