ID A0A0V0V9L4_9BILA Unreviewed; 1297 AA.
AC A0A0V0V9L4;
DT 16-MAR-2016, integrated into UniProtKB/TrEMBL.
DT 16-MAR-2016, sequence version 1.
DT 27-MAR-2024, entry version 29.
DE SubName: Full=Neurogenic locus notch-like protein 1 {ECO:0000313|EMBL:KRX60214.1};
GN ORFNames=T09_8675 {ECO:0000313|EMBL:KRX60214.1};
OS Trichinella sp. T9.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Enoplea; Dorylaimia;
OC Trichinellida; Trichinellidae; Trichinella.
OX NCBI_TaxID=181606 {ECO:0000313|EMBL:KRX60214.1, ECO:0000313|Proteomes:UP000054681};
RN [1] {ECO:0000313|EMBL:KRX60214.1, ECO:0000313|Proteomes:UP000054681}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ISS409 {ECO:0000313|EMBL:KRX60214.1};
RA Korhonen P.K., Edoardo P., Giuseppe L.R., Gasser R.B.;
RT "Evolution of Trichinella species and genotypes.";
RL Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00076}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KRX60214.1}.
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DR EMBL; JYDN01000062; KRX60214.1; -; Genomic_DNA.
DR Proteomes; UP000054681; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR GO; GO:0048468; P:cell development; IEA:UniProt.
DR CDD; cd00054; EGF_CA; 5.
DR CDD; cd01767; UBX; 1.
DR CDD; cd22249; UDM1_RNF168_RNF169-like; 1.
DR Gene3D; 3.30.70.3310; -; 1.
DR Gene3D; 1.25.40.20; Ankyrin repeat-containing domain; 2.
DR Gene3D; 2.10.25.10; Laminin; 7.
DR InterPro; IPR002110; Ankyrin_rpt.
DR InterPro; IPR036770; Ankyrin_rpt-contain_sf.
DR InterPro; IPR001881; EGF-like_Ca-bd_dom.
DR InterPro; IPR013032; EGF-like_CS.
DR InterPro; IPR000742; EGF-like_dom.
DR InterPro; IPR000152; EGF-type_Asp/Asn_hydroxyl_site.
DR InterPro; IPR010660; Notch_NOD_dom.
DR InterPro; IPR029071; Ubiquitin-like_domsf.
DR InterPro; IPR001012; UBX_dom.
DR InterPro; IPR013087; Znf_C2H2_type.
DR PANTHER; PTHR24044:SF511; EGF-LIKE DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR24044; NOTCH LIGAND FAMILY MEMBER; 1.
DR Pfam; PF12796; Ank_2; 2.
DR Pfam; PF00008; EGF; 3.
DR Pfam; PF12661; hEGF; 2.
DR Pfam; PF06816; NOD; 1.
DR Pfam; PF00789; UBX; 1.
DR PRINTS; PR01983; NOTCH.
DR SMART; SM00248; ANK; 6.
DR SMART; SM00181; EGF; 7.
DR SMART; SM00179; EGF_CA; 7.
DR SMART; SM00166; UBX; 1.
DR SUPFAM; SSF48403; Ankyrin repeat; 1.
DR SUPFAM; SSF57196; EGF/Laminin; 7.
DR SUPFAM; SSF54236; Ubiquitin-like; 1.
DR PROSITE; PS50297; ANK_REP_REGION; 1.
DR PROSITE; PS50088; ANK_REPEAT; 1.
DR PROSITE; PS00010; ASX_HYDROXYL; 1.
DR PROSITE; PS00022; EGF_1; 6.
DR PROSITE; PS01186; EGF_2; 4.
DR PROSITE; PS50026; EGF_3; 7.
DR PROSITE; PS50033; UBX; 1.
DR PROSITE; PS00028; ZINC_FINGER_C2H2_1; 1.
PE 4: Predicted;
KW ANK repeat {ECO:0000256|PROSITE-ProRule:PRU00023};
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157, ECO:0000256|PROSITE-
KW ProRule:PRU00076};
KW EGF-like domain {ECO:0000256|ARBA:ARBA00022536, ECO:0000256|PROSITE-
KW ProRule:PRU00076}; Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000054681};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Signal {ECO:0000256|ARBA:ARBA00022729};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 874..896
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 252..328
FT /note="UBX"
FT /evidence="ECO:0000259|PROSITE:PS50033"
FT DOMAIN 331..368
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 369..410
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 413..449
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 450..487
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 602..638
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 640..676
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 678..714
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT REPEAT 1151..1183
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REGION 223..249
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 143..174
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 227..246
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT DISULFID 358..367
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 400..409
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 417..427
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 439..448
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 477..486
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 628..637
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 666..675
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 704..713
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
SQ SEQUENCE 1297 AA; 145006 MW; A71C59201B749340 CRC64;
MEDNDNSTLA EMGFPQHHID LARQITGSSD IQVLCDWLMA NSLTLDEADK GETAVEQKLL
EEMKSIEDRH QVGDLEKMDL KQAKTEAPLE NQPEKKVTYM KCNDCGRLLS SQKAMKQHSL
EFKHCNFSEV EDTVAEEEKK KTTQNLYIRM QEMAKQREEK EQRKEIEAEK ERRKMGLEMA
DYRRRLELEE IKQMVKQRKQ QKHDDYLAKK KILDEIRMDR EARQLQKSKA ASASEPSASS
SVGEEEKASI GNDLETCTLQ FRMRNGSKVV KEFKKTQTWA DAKLFADNFF GSERLEYFTT
FPTRFFNEED KSKTLLDMKL HPSAVIHVRS LNQKCELNLC KNGGYCFLNE HGNAQCECTP
GYVGKHCQTV DICMSNPCKN GGSCVYQIEE DEIVSFTCLC PLGLTSTFCE NPLPNACDSL
PCKNGICELE TLDSFHCRCE SGYEGKFCEN FTRCKYNLCN NGGQCMVLPD GTYRCVCPKG
FAGSTCESDI DECTRDICEH GKCTNLFGDY QLSISIDVPV YFDSIVLLGV LAVHASRALV
GKIVIKCNVR AVRFCATTTA TASKLLQTTI AFVSQSTNYP PTLSSSSSSS LLGFTGVHCE
VEHFNCQQTV CENGGICVIA NGTSKCLCTE PYTGATCGTG IGSCFYNPCY NGGVCHEFND
HFTCACPAGI TGKYCEITSN RCSANMCLNG GTCFNYNDTF FCSCPDGIFG RRCQFYEAGV
EQVEYEDIVI VVLVEPRTFM STLSELLAII NSHMHINITL KKDELSLPKV YSWNSQSGYD
KNSNAVLFNN TDETGNNNWK FLIANQADAI YGTLAVMTIS SSACTRENSK SCVAKFGEVI
NQLASDAQFD YLKSRVSWKI NTVDRKKKSE ISNFLPLIVT VISSLVLIIF FVLLMLQRKR
LHAATWHPPV EEGPVNLNTT LRSNYLTPLA SVLQKSTTDK KATNGAQKIF LKSKQDSFCA
TDSQTVDQEK RYATSRDTYK WSDLHLCIIH GVLVDPETIT DDQVNALGPD DQTPLMVAAE
RCTSDVELQF MIMLLNAGAK MEAQTELLKE TALIIAIRHS RLQAVLALIN FRCSLETADV
DGNTALHHAV MTRNTEILCA LLDSELCNTE TRNNDGLTPF VLNAKVCGAV DTEIAFLLLS
SGASIDSTDD EGMHAVHYAA INGNIPLLEL LFQRYTNINL MDCYGRTALF FAVREKHTEA
VEWLLQVGGV CIPIDDGHYA TITFPSAPDG ETFQFPAVQL DDFPNISDSP KDACCTDLTE
EQSYQFPHST SHFETLHTDT TETFIPTQQQ YWSWCFS
//
