ID A0A0V0VA52_9BILA Unreviewed; 1437 AA.
AC A0A0V0VA52;
DT 16-MAR-2016, integrated into UniProtKB/TrEMBL.
DT 16-MAR-2016, sequence version 1.
DT 27-MAR-2024, entry version 16.
DE SubName: Full=Protein patched-like protein 1 {ECO:0000313|EMBL:KRX60257.1};
GN Name=ptc-1 {ECO:0000313|EMBL:KRX60257.1};
GN ORFNames=T09_3321 {ECO:0000313|EMBL:KRX60257.1};
OS Trichinella sp. T9.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Enoplea; Dorylaimia;
OC Trichinellida; Trichinellidae; Trichinella.
OX NCBI_TaxID=181606 {ECO:0000313|EMBL:KRX60257.1, ECO:0000313|Proteomes:UP000054681};
RN [1] {ECO:0000313|EMBL:KRX60257.1, ECO:0000313|Proteomes:UP000054681}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ISS409 {ECO:0000313|EMBL:KRX60257.1};
RA Korhonen P.K., Edoardo P., Giuseppe L.R., Gasser R.B.;
RT "Evolution of Trichinella species and genotypes.";
RL Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the patched family.
CC {ECO:0000256|ARBA:ARBA00005585}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KRX60257.1}.
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DR EMBL; JYDN01000062; KRX60257.1; -; Genomic_DNA.
DR Proteomes; UP000054681; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR Gene3D; 1.20.1640.10; Multidrug efflux transporter AcrB transmembrane domain; 2.
DR InterPro; IPR003392; Ptc/Disp.
DR InterPro; IPR000731; SSD.
DR PANTHER; PTHR46022; PROTEIN PATCHED; 1.
DR PANTHER; PTHR46022:SF1; PROTEIN PATCHED; 1.
DR Pfam; PF02460; Patched; 1.
DR SUPFAM; SSF82866; Multidrug efflux transporter AcrB transmembrane domain; 2.
DR PROSITE; PS50156; SSD; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000054681};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 140..159
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 607..627
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 639..663
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 675..694
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 715..738
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 744..767
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1137..1157
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1163..1185
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1192..1211
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1231..1251
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1258..1287
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 608..767
FT /note="SSD"
FT /evidence="ECO:0000259|PROSITE:PS50156"
FT REGION 1..23
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 809..831
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1368..1397
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 809..825
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1437 AA; 160003 MW; CBA6F31979F1C19E CRC64;
MDINTDKGKT ASAPVQDPES GRFTTRSISN AASIVKMGRA KLCLYDRELQ RMLPAQVAPP
LQPRCISRLG RLPSDMVQID TSKWGEEFRR RPSWVDAGMA LRLIQSDKAK GNKPALWIRM
LLQRGMLCLG HRIQRHAGQV LFFGLLMLSI CCIGLRLVAF ETDMEKLWIE KGGRLEEERN
FLSENSARLP NGKLRSVEHA DNRDEVMVAN TGDAFLILIQ TPRKGKSNIL TKDDLLLHEK
VVSEMGRMTI SLFGETWGLE DICFRPPSPS IEGAISEIIK VLLDKIIPCT LITPLDCFWD
GSKPLGPNPP LKIGAEIQTF VPSLQDQVTW KNLNPQGVID DVKTLGIFDI SIFDNFLERS
GIASAYQHRP CIEPLDPECP STAPNYINMC PVVEKFLAWN LKTKQYSFPN ITMDVEKLLM
GNDTVDSTEP TTTTKPKETS MYEQEYNTFE EMFGSIREKP VMTEPKICRL FKEDVRSLLL
ANETLSRQFL PAAAFTNYST IMTGGCRGYA ENFMKWPEDL IIGGITKKDG IIQTAAEVYE
RFASSHSEST LARVNWSIEN AQSVLTAWQR NFSNLIYDYA NNTAENRQVH PMSGTSINDM
LEMFSELNPT VMIVGYVLMV FYASFSLCST DDGGVASGVG LAVCGCILVT ISSLAGLGCS
MLLGVKFNPT TTQVVPFLSL GLGVDDMFLL LHNYRDIARQ YQVDQIGMLL KETGLSALLT
SVNNILAFLV GALLPIPALR SFCIQVALVL LLNAVTILTI YPALMTFDLA RRKRRLLDVF
CCIRAPQPKS RLNSRSEPVS VVYEKVNSGQ MNKSNNSNSV SKSPVGENEP KKRRCHLTGI
TVENFLKYIY GPLITRTPVK IGIVVFNLVL VALSIDGVTK ISLGLELTDL IPKHTAPYGF
LAAREAYFSF FPFSAVLKGP MDIPHKQRLI REYRSAIGEI DYVIRHDGQP SEKYWLSMMT
EWLVSLQQKF DEDWQKGYIN RSGVISTLVS NDAKLAYKLL CNQGDILDCG RVGTTRLIDR
EGLINPDGFY NYLTAWFNLD QMSYYISQAN FYPQPPIWYN TDHIRSDTDN KVPPAVCPTV
SHIPFFVTNL VDTASVVDLI NKVRSICEEY TAMGLPNFPE GLPFNFWEHY VHLNRNLLLA
LLMISASVFV IVSLLLFSPW TALLVVTVVD LMVFELAGFM GMIGLKMNPV SAVTLITAVG
IGVEFTVHMS LSFLTALGSR DQRVQMAVDH MFVPVLHGGL STLLGLIMLA FSEFEFIVHY
FFLVMSCLIL LGIINGLFLF PVLLSWLGPP GEVRTIDGSD SLPPPSPSLV AKQLASLSKK
SNQGAYFGLA RASQKGYRRQ SDMSLSTITE ERTPPNSATP PVLTITPVQA GNNSPAVEVT
SSTVTPRIHS SLPNVTNDLT QMENGEDGRS NRFSNAFTRF GNSIRRSLGH QSQQKPV
//
