ID A0A0V0VJP8_9BILA Unreviewed; 660 AA.
AC A0A0V0VJP8;
DT 16-MAR-2016, integrated into UniProtKB/TrEMBL.
DT 16-MAR-2016, sequence version 1.
DT 27-MAR-2024, entry version 28.
DE SubName: Full=Eukaryotic elongation factor 2 kinase {ECO:0000313|EMBL:KRX63633.1};
GN Name=efk-1 {ECO:0000313|EMBL:KRX63633.1};
GN ORFNames=T09_8244 {ECO:0000313|EMBL:KRX63633.1};
OS Trichinella sp. T9.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Enoplea; Dorylaimia;
OC Trichinellida; Trichinellidae; Trichinella.
OX NCBI_TaxID=181606 {ECO:0000313|EMBL:KRX63633.1, ECO:0000313|Proteomes:UP000054681};
RN [1] {ECO:0000313|EMBL:KRX63633.1, ECO:0000313|Proteomes:UP000054681}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ISS409 {ECO:0000313|EMBL:KRX63633.1};
RA Korhonen P.K., Edoardo P., Giuseppe L.R., Gasser R.B.;
RT "Evolution of Trichinella species and genotypes.";
RL Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KRX63633.1}.
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DR EMBL; JYDN01000029; KRX63633.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0V0VJP8; -.
DR STRING; 181606.A0A0V0VJP8; -.
DR Proteomes; UP000054681; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0004686; F:elongation factor-2 kinase activity; IEA:InterPro.
DR GO; GO:0003746; F:translation elongation factor activity; IEA:UniProtKB-KW.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR CDD; cd16967; Alpha_kinase_eEF2K; 1.
DR Gene3D; 3.20.200.10; MHCK/EF2 kinase; 1.
DR Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 1.
DR InterPro; IPR004166; a-kinase_dom.
DR InterPro; IPR047588; eEF2K_a_kinase_dom.
DR InterPro; IPR011009; Kinase-like_dom_sf.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR PANTHER; PTHR45992:SF2; EUKARYOTIC ELONGATION FACTOR 2 KINASE; 1.
DR PANTHER; PTHR45992; EUKARYOTIC ELONGATION FACTOR 2 KINASE-RELATED; 1.
DR Pfam; PF02816; Alpha_kinase; 1.
DR SMART; SM00811; Alpha_kinase; 1.
DR SUPFAM; SSF81901; HCP-like; 1.
DR SUPFAM; SSF56112; Protein kinase-like (PK-like); 1.
DR PROSITE; PS51158; ALPHA_KINASE; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Elongation factor {ECO:0000313|EMBL:KRX63633.1};
KW Kinase {ECO:0000256|ARBA:ARBA00022777, ECO:0000313|EMBL:KRX63633.1};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Protein biosynthesis {ECO:0000313|EMBL:KRX63633.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000054681};
KW Serine/threonine-protein kinase {ECO:0000256|ARBA:ARBA00022527};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT DOMAIN 91..305
FT /note="Alpha-type protein kinase"
FT /evidence="ECO:0000259|PROSITE:PS51158"
FT REGION 387..433
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 387..407
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 660 AA; 74543 MW; 785C4A4930CC0481 CRC64;
MDKKNAVSIN TAIDDEMLIY PFHESPPPAK CGEEFAVGQE LVARNASEGD LSKNKIRMKW
RQMVKKVLRV PDPWEMLKLN SSPVEQCLRY RYSALRGEWV TDKVYVKIED EPFDRGAMRI
CYRLKKCPGV HGDVPSDWSK ATNFVAKRYI AQSVSRETYF EDVRLQMDAK LWSDEFNRHN
PPKKIDIFQV SIVEFVNRQE KPLFHLEHFI EGNYVKYNSN SGFVLSSSVY RQTPQAFSHF
TFEMSAHQLI VVDIQGVGDL YTDPQIHTSD GVGYGDGNLG TKGMALFFYS HACNSICRSL
NLAEFDLAPA ERASRKKSYA IKQHLSETVV RDATQRCRDF CPSSGIRAMD YVRARSATSM
MAANSGDFTP LSPGHYPDVF NFAESSDETS SSEVNGSSSS SALPMEAAAT TTGRRRIDSE
VDSSSKQDSM RNQYWAGRRG KSLPACIITQ QLHLHNSEDN ILGRIHLDLA RYHELGRFVQ
PDTQYDRSAA WFHLEKAAEC GVHEAVMTMA KIYLGVEHEL LQDFMEDGTT DENINQGLKL
AEKLAVNGDR WATMILAERY ASGQLLGSER KQSYKTALFF YNKLLEQVDP KGNVDIAIYE
IHAMIADLYR TGGTDLKKDI NLAVYHYNEA AALAIENLKG KLAMKYYTAA EQCAAEDEGE
//
