ID A0A0V0VLI5_9BILA Unreviewed; 5532 AA.
AC A0A0V0VLI5;
DT 16-MAR-2016, integrated into UniProtKB/TrEMBL.
DT 16-MAR-2016, sequence version 1.
DT 27-MAR-2024, entry version 20.
DE SubName: Full=Twitchin {ECO:0000313|EMBL:KRX64380.1};
GN Name=unc-22 {ECO:0000313|EMBL:KRX64380.1};
GN ORFNames=T09_9953 {ECO:0000313|EMBL:KRX64380.1};
OS Trichinella sp. T9.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Enoplea; Dorylaimia;
OC Trichinellida; Trichinellidae; Trichinella.
OX NCBI_TaxID=181606 {ECO:0000313|EMBL:KRX64380.1, ECO:0000313|Proteomes:UP000054681};
RN [1] {ECO:0000313|EMBL:KRX64380.1, ECO:0000313|Proteomes:UP000054681}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ISS409 {ECO:0000313|EMBL:KRX64380.1};
RA Korhonen P.K., Edoardo P., Giuseppe L.R., Gasser R.B.;
RT "Evolution of Trichinella species and genotypes.";
RL Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KRX64380.1}.
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DR EMBL; JYDN01000024; KRX64380.1; -; Genomic_DNA.
DR Proteomes; UP000054681; Unassembled WGS sequence.
DR CDD; cd00063; FN3; 28.
DR CDD; cd00096; Ig; 3.
DR CDD; cd05748; Ig_Titin_like; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 54.
DR InterPro; IPR003961; FN3_dom.
DR InterPro; IPR036116; FN3_sf.
DR InterPro; IPR007110; Ig-like_dom.
DR InterPro; IPR036179; Ig-like_dom_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR013098; Ig_I-set.
DR InterPro; IPR003599; Ig_sub.
DR InterPro; IPR003598; Ig_sub2.
DR PANTHER; PTHR14340; MICROFIBRIL-ASSOCIATED GLYCOPROTEIN 3; 1.
DR PANTHER; PTHR14340:SF9; TITIN; 1.
DR Pfam; PF00041; fn3; 27.
DR Pfam; PF07679; I-set; 25.
DR PRINTS; PR00014; FNTYPEIII.
DR SMART; SM00060; FN3; 27.
DR SMART; SM00409; IG; 25.
DR SMART; SM00408; IGc2; 22.
DR SUPFAM; SSF49265; Fibronectin type III; 16.
DR SUPFAM; SSF48726; Immunoglobulin; 26.
DR PROSITE; PS50853; FN3; 28.
DR PROSITE; PS50835; IG_LIKE; 19.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000054681};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT DOMAIN 7..99
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 110..204
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 216..311
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 439..527
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 691..783
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 832..918
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 923..1002
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 1016..1107
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 1301..1394
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 1398..1490
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 1495..1591
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 1597..1690
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 1717..1808
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 1816..1909
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 1912..2009
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 2008..2102
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 2110..2203
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 2212..2306
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 2310..2401
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 2407..2503
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 2509..2604
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 2704..2797
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 2803..2897
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 2901..2990
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 2998..3090
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 3096..3190
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 3291..3384
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 3390..3484
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 3488..3572
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 3582..3676
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 3682..3777
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 3781..3868
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 3875..3969
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 3975..4071
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 4077..4172
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 4275..4369
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 4375..4470
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 4474..4564
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 4571..4667
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 4673..4768
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 4771..4868
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 4873..4956
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 5063..5157
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 5163..5259
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 5264..5352
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 5357..5448
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 5480..5532
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT REGION 603..654
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 802..827
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1590..1610
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2185..2216
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2878..2903
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 620..654
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 804..826
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1590..1607
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2187..2203
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 5532 AA; 614154 MW; D87412797EC2C345 CRC64;
MPGGKAPRFT QKPVIKQTPE GHLLMECLLD SQPNPKVQWF HGSKPVTDNA RYTLNSKHLG
KEQHLVTLLI KDPTADDRGT YKCNVANEFG DSNANINLNF AAEEESKIKP PVFLTKPKII
PKNDGAIILM ECRVKSAVLP TATWIHNGAP VQAGGRVKIT AVKEPDHTYL FELELHDLVP
EDSGLYKCTV KNDAGETNAN LTLNFDIPPE PADFSPTIAE KPSITTSADG TVVSLKCVAK
AKPKPKATWS LDGVPLKESA KLVHHEETVG PNLYLFRLDI MNPTEKSAGI YKCSLKNKLG
ETSANVNLKI DAEELKQKLE RKPIFLPRIE PTVDADRIFI ECKFQSDTSP KAIWKKDNKI
LSQSEQITKK LTSNGKGQYT ASLSVKNPTD RDSGKYELFL ENSAGKTETS FPIVVPEMKR
LKATSPSPVP KKKSSAKPPM FTNELHNESV EEGATAILAV TLECDTSTKL IWSRNGLQIS
TGGNFETFFD GSAGRLTIKN VKKQFGGTYV CTAESRFGNA KSSCRLTVES KGKCSFLIII
FCETLTNDSI PTIEMQMDDD QSQAKTSIAT DYSEDEMTES ISELPSVSMK PPQISRRHTE
ADAELFAQPH VGRGARRSSL RPGEIAEETF RRSSNAREPS NEKHGHRRSS DWSYLERRAS
SVEITSESVQ ELLEKPTGPL MPLPENTPAA PKITEIPENV TVLEGETALV SCSVQGNPVP
TFRWMKAGRE VLPGGRYKHL THTDNNTVTL VIGKAKLEDE DAYDLIAENE HGTDQATIKV
FVTNAAGVDF RSLLKHRQYE KWGKHKHKGD SGDLKPGDDQ QRRASMLPDK KPSFWEIEIQ
DQRVQQTVHK EAKFECKFCR PKAKIRWYKQ KQEIFTGMKY KIINDKEFCT LIINNPDQDD
ASKYTCVANG IPTTAMLYVE DPPTKFTFEK PLPTSTELIR TREGILECRV SHPDAPVKWY
KGDDELKPSS KYSMEIDRFG RCVLIIANVD YDDMGEYTAK INKDNVTSCC VAVGNPRCEF
ISPMKSQKVQ EKENASLECE LNDKAAEVTW YHDESKITID KVKFEEVRIG RKRKLIIKNC
GVEDEGVYKC MTSDDQTMGQ LIVEPLNKFL EKLTDKTVVE KDDVTLQCQT KDTHGAATWF
KNGKQITPMP GGKFETKSKN GTHTLLIRKC ELTDDDKYEV EVGGLKGECS VSVLEAEKKP
IFTGKPQKIE AEAGKPITVS IPYMVKGTRK ADPVATVSHN GTALKLKSGD QIKVTVTADS
VEIEFKDPKM ADDGKWDITL SNSAGSTTTN FQMEVRDRPG PPEGPLEIAD LKATECKVKW
RPPKDTGNSP IHHYLVEMLD GTTGEWKKLG QSKACEMKVP NLIKGQNYKF NIVAVNKIGV
SDPLIGGEFI AKDPDCKPTL DKVALKNLKV KVGEVIKYKI DIGGEPPPTA IWLFGDQPVK
QNVRAKVVTT AKETELTVSD AERGDSGKYT LRVKNSLGEE TGVGLVIVVS KPAKPTGPLV
VSEVNKEGCK VAWNAPEDDG GEPIEEFIVE AQESGKGGDF FEVARCGPAE KEAVIKGLKN
KGKYNFRVKA KNKEGVSDAL VTKEATLIKD PWDEPGKPGK PEITDSDKDY VTLSWTPPTS
DGGAPIEKYV VECKEKNSKD WKPVGESAKT TATINQGLKE GNEYQFRVIA VNKAGPGEPS
QPSSIHVMKP KFSMKKLFID VVFTFIYYEK NFNTAAPWID LNSMGNLVIK AGQEAKFSPK
IGGQPPPKVT WTKVGSGQIN EGSRIHFKDS KPGIAVLTIL KAVRGDCGDY MINVKNQKGE
QSATASLTVL DRPTPPKGPL KVTDVFENEM TLHWQMPEDD GGVPVEAYEV EKFDVDHGRW
IPCGRTNEEK ITVHNLVPGH SYLFRVKAIN KEGESDALAL TDPVLAKNPY DPPTKMEKPN
VTDWDSDHVD LEWKPPENDG GAEIEKYIIE KKRKNDKWVP ALEVSPDKLE ARIGDLTKDE
QYQFRIIAVN KAGPSEPSEP SNRVIAKPRF LAPLINREDL PMTTVKVGQL IKFNVRIIGE
PPPEVFWEKD GKKLSSSAEL TIENPDYLSK FFINKSARKH AGIYKITAQN SSGVDVAEVT
ISVLGKPSKP KGPLEVKDVF ADHMTLSWNA PEDDGGTPIE CYEIEKCDPA TGIWIPCGRT
ADTNFVADGL LEGNSYEFRV KAVNSEGESE PLQTDTSIKA KNPYSYEPNP DKPNKPEVVD
WDIDHVDLAW SPPQNDGGAP IEEYVIEKRT KYGRWEPAAS VPGDATSVTI SDLTPNDEYE
FRIKAKNKGG FSDPSDPSEA VITKHRNLPP KIDRSAMQPV TVKAGQVIRF DVPVEGEPPP
TMTWFHEGEI MKPKGNIKIE NGDYNTKFAI RLAERSDSGV YTLKAVNVNG EDEATVKVEV
TDKPSAPEGP LEAKEVYGDH ITLGWKAPED DGGIPISHYV VEMLDPQLGH WVVAGKTPTG
DSTEYTVENL IPGHDYKFRV KAQNANGESD ALETTKPITA KNPYDEPGKP GQPQVMDWDE
NFIEIGWTPP ESDGGAPIES YIVEIKEKFS PFWSKAGETP ADVTAFKVTD LTPGNEYQLR
VRAKNKAGPG EPSDETERVV TKARRVPPKF NKEIIQDIRL KAGQHYRLEI PLIGEPAPQL
SYAFNNSPID VSDRLKFEQR EHDVLFVIKR ALRTDTGFYL ITAKNEYGED TARLNVTVLD
HPSKISDLKV SDIHKDGCKI SWQAPEDDGG SEISHYVIEK EDIANGRWVT AAETPSCEAD
ISGLHPNHEY RIRVKAVNRN GESEPVVCDE SFIARDPFEE PDKMLPPVVL DWDKDHVQLE
LIKPESDGGA PIEKYVVEMK CNNGEWMPAV EVPADQNLVT VPDLKEGQKY QFRVKAVNKA
GSGQPSDPSK TVTAKPRHLP PKIDRSTLHS VKIKAGQKLE FDVNVEGEPP PQIRWLLNGE
SLGSSERTRV VNKDYNTTLR TVDVKRFDSG VYKIIAENES GTDEAEVMVT ILDAPTAPRG
PLQVSDVHSE GCNLAWKPPE DNGGSDILNY VIEKQEDGGR WVECGTSYDT EFKVGKLKPG
EEYNFRVKAV NRQGESKPLT TSTSIVAKNP YDTPDKPENL KVIDWDKDHM DLQWQPPVND
GGAPIEKYLV EVKSRLDDWK PAVEVTADTC KATVPGLTPR ESYQFRVRAV NKAGPGKPSE
ETAPMIAKPR RLAPKLKLDD LFDIRIKAGQ PLSIVVPFEA EPQPLIIWMH EDIKLESNDR
TEIEHVENLT SVEIPRSVRS DTGPYTIILQ NEYGEDKGVV NVTVLDVPLA PEGPLKVKDV
TKQSCNLSWK PPNDNGGSEI IHYVVEKMDT SRGTWQEVGE FPDCEAKVNR LIPGKEYKFR
VKAVNSLGES KPLTTEASII AKDPFDVPSP PEELTVVDWD RDFVALQWKP PENDGGSPVS
EYIIDVREKG NPFWCEAGRT GGNKPSFCVK NLKEGAAYEF RVTAVNDAGP SNPCDTVCAA
AKPRRLSPKI LTTIRLIKVR AGMPLRMPVD FIGEPAPDVS WTKEKASLNE RIQIENTEGK
TELFISSAKR CDTGPYNLRL TNEYGQDQGE FQFLIQDVPG VPEGPLEAVE ITKDSVVLSW
KPPLDDGGSE VTNYVVEKRD THSDVWNLVS SFVPGTTVKA LKLTEGHSYE FRVMAENAFG
RSEPLSTIRP ITAKDPFAPP DKPGAPVVKA HDRDFIAIEW QKPLDDGGSP ITHYDIERRH
NKTGRWIKIN QDPVKSLKFQ DNRVNEGHLY EYRVVAVNEA GSSEPSDPSS AVYAKPMFEV
PKFLLDLNGK EVRIKAGEPL DLNIPFTGSP TPTIEWIKDN ISVPESSLNT DDQHTQLYIA
HSKRSDSGDY KIMAKNQSGT AEALVKVVVI DKPSEPRGPF NYTGISKHSI KLEWNPPDDD
GGSEIIGYAM EIQEFGSPVW EKIRDYIPST SYTVKGLDEG RQYLFRVRAE NMIGLGEPLH
SVPMTAKPSY DVPGAPSAPE VTGYDNTYIS LKWNPPRSDG GSPITEYIVE KHEKKGGGDW
SPCYTSHSTS CECVVKNLVP GESYQFRVRA VNLAGEGPPS RFSEPCTCQP FIHPPGPPDS
PRVGKVTKRS VDLTWNRPLK DGGSAITGYM IEKKPFVSNE WIPCNTQPIL GTEFTVTGLP
EGEQFMFRVI AVNKAGPGEP SKPTENIIIQ DELGKPYIDI GSVKDVTVRA GEPYTIQIPY
TGGNPKPTVS FLNNDNEIFD EENRVKITVT DDCAILENLC SKRSDTGPYK VSLSNRYGKD
SCKFKVKVLD RPSPPVGPLE ATNVDADAIT LHWLPPKDDG GEEIRNYIVE KKEPNSDEWK
TVNASVMGTS FRVRNLKEGN QYEFRVRAEN QYGISDPLTT MEPVVAKSQH QPPSAPGIPE
ACGTSEDFIN LTWTKPFYDG GQPITGYIVE KREKGEENWI RADFGMFPDT KAKITSVIPN
KCYEFRVCAV NSVGAGPFSQ TSLPIYAQYP PSAPKIDISL LTRDIYTVVG SPLSINVSYS
AVPNGTVTWT KGSEILLSND HLNVEQNENI AVVSTKSCVR SDSGIYTVVV QNSLGSDSAT
IRVTVFDRPS PPLGPIIHSD ITPESCVLSW LSPKDDGGSP VTNYVIEKCT TDQPDNWERV
SSFVRGLRYE VIGLVPKASY KFRIRAQNEY GTSDPLESDL PIVTKYQFDV PSPPGTPEAV
DMDTTWVTLT WDRPNSDGGS KILGYLVEFR EPDSYKWTSA NAFLAKEPRL VIESLRDQSE
YQFRVLAKNA AGFSKPSEPS SFIKLKPKFS PPGAPSLPYT DRIGRNYVTL MWEPPLLDGG
SKITGYIVER REVGSYSWIR CNDYNIRDPE FTVPDLVEFK DYEFRVSAVN SAGRGAPSPV
ATVKVQESGG FKPEFVRKLF NTVVPLNRKA VFECEAIGKP TPVVRWIRHG RDISDCGRYK
VEEFETKYTL TIEEVWDIDN GEFACEATNQ FGSDVTVAVL KIQEPPVIDK EPGNQTYSEE
ELARIKIFFH GDPEFSCFLN QNGREISADD DFVKLVAFDD HVLITLNSVR KQDAGRYEFT
VQNESGKATC VFYVYVTGLP GPPIGPLLIT DITQHSAMLQ WKPPREDGGT KILYYLVEKR
DLAREEWTTV ANSVKELSVQ ALGLFEKHEY SFRVSAVNEN GQGPPLDADE PITAKFPFDP
PLAPGIPDII SVTSDYLSLS WDRPKRDGGD TVAGYVIEKK EEGTELWQRC NAVPIPQTVF
NVPNLIDGRK YLFRVFAVNA AGMSPPAECA SPVTFSPNSS AKAPEIVTPL RNVSGEEGRS
VRLECEITGD PAPEIRWFKG ARDITNGGKH SIFSIGNKHV LVINDLFGED ADEYSCRALN
IAGCRSTTGE VFIKSAPKIL LPPHYQATVE FRKGETVSLK IPFRGYPQPT AVWTKQGSRC
CSEGRFSIET VDRLATLNIS NSSKEDSGTY ELRVENELGF DVSSVEIRIC GISYFLFPDK
FLCRSTYLMI FFFSPDRPDP PQCPAVETIL DNAVILSWKP PVDDGGSDIS NYLIEKRQLP
NSDWMPCVKS RQ
//
