ID A0A0V0VQE8_9BILA Unreviewed; 1832 AA.
AC A0A0V0VQE8;
DT 16-MAR-2016, integrated into UniProtKB/TrEMBL.
DT 16-MAR-2016, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE SubName: Full=Signal-induced proliferation-associated 1-like protein 2 {ECO:0000313|EMBL:KRX65621.1};
GN ORFNames=T09_8621 {ECO:0000313|EMBL:KRX65621.1};
OS Trichinella sp. T9.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Enoplea; Dorylaimia;
OC Trichinellida; Trichinellidae; Trichinella.
OX NCBI_TaxID=181606 {ECO:0000313|EMBL:KRX65621.1, ECO:0000313|Proteomes:UP000054681};
RN [1] {ECO:0000313|EMBL:KRX65621.1, ECO:0000313|Proteomes:UP000054681}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ISS409 {ECO:0000313|EMBL:KRX65621.1};
RA Korhonen P.K., Edoardo P., Giuseppe L.R., Gasser R.B.;
RT "Evolution of Trichinella species and genotypes.";
RL Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KRX65621.1}.
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DR EMBL; JYDN01000016; KRX65621.1; -; Genomic_DNA.
DR Proteomes; UP000054681; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.
DR GO; GO:0051056; P:regulation of small GTPase mediated signal transduction; IEA:InterPro.
DR CDD; cd00992; PDZ_signaling; 1.
DR Gene3D; 2.30.42.10; -; 1.
DR Gene3D; 3.40.50.11210; Rap/Ran-GAP; 1.
DR InterPro; IPR001478; PDZ.
DR InterPro; IPR036034; PDZ_sf.
DR InterPro; IPR035974; Rap/Ran-GAP_sf.
DR InterPro; IPR000331; Rap/Ran_GAP_dom.
DR PANTHER; PTHR15711; RAP GTPASE-ACTIVATING PROTEIN; 1.
DR PANTHER; PTHR15711:SF70; RAP-GAP DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF02145; Rap_GAP; 1.
DR SUPFAM; SSF50156; PDZ domain-like; 1.
DR SUPFAM; SSF111347; Rap/Ran-GAP; 1.
DR PROSITE; PS50085; RAPGAP; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054};
KW GTPase activation {ECO:0000256|ARBA:ARBA00022468};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000054681};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 6..25
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 903..1120
FT /note="Rap-GAP"
FT /evidence="ECO:0000259|PROSITE:PS50085"
FT REGION 86..105
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 172..199
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 213..276
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 392..477
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 578..650
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1443..1467
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1485..1505
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1593..1625
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1787..1832
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 228..242
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 249..276
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 392..418
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 435..457
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 578..614
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 631..645
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1485..1504
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1832 AA; 200423 MW; 5F1AC2392B1FE301 CRC64;
MTFACWRLAI SCFVPVPILV TLLFLKCKKN RHGQIQLLID SLPSGCRWTL TSVGPLKRSS
RPAGLVTAVN KISTLGLDSS GGKAAAIGQR GRLPPAPTAS PASAGDSYGV KLRRISQGVR
ARLLNRPFSC DVDTLCTLPS TVDDASTAAT VDNNGSLTLK PGSFFKSKLR NVGHHHHHHH
HHNHQDEASV KATAPSCSGS EDAQMEFTFG QVDLQSGLQR TPKAAPSKRK GSLKERFSLF
RRSVASDCEP SPNEESIPSS AHFQQQKKKN RVSSTTRSLS QLDLSSCHNF PVEETASVDN
GNIIHKHHLA KFSSSQGADL VTNCPGDISG KPFSLSAGST LSNFSTPPGT MTTVSPLCEK
EVCTKYRNNV TTTNSNYHHT NNNKTTDHVH FIASLSPGDN GSSSSSSQQP SSVLKQQRTL
RRAKAVDLGG CSTDLTHHPL SSSPRSHNAS NFPSSLSDGF KKVARKESRK PHGTRKAAND
SILKKLIVAG GKAFSEDSSL RIMNSVASMV AGTRQEVATE CWAPAVEERG RKLFFSHYDC
HSICADSGQL LSNFSLRTSQ TRDGGGCMHA HASGTATVTQ PGSVAGSGSF PSSGSSSSSA
AAVLPRNSGN TVGVGGTLDF LPGASPMDSG SVDDGPSSSQ APQSPVDEGD GKCNALVTAC
PFFRGEIGGE PTRHVSLGTE RYRRRWIVQD VSNSSADTAL ASDPLLPNSA DPTRPTLTAK
EHLETWHRIP SAAEACVLEN LGNVYLGGRL CAYRQPQLVI EHVDHGAFYY RHCFLGKAHQ
NYFGIDENLG PVAISIARDK LDVIQARLSN LSSPYVYRII IRLSDLSTFR GSIIEESLPS
YQLTKEQAQT VSQPMSPTGF ASGLVSSSST KIPVKEILEL VIPELTSSCL KLAVPLPRTE
EMLLKLDEQA IYTRYKVGVL LCKANQCTEE HMYNNEFSTP AFEEFLDILG DRIRLKGFDK
YKGGLDNKGD STGTHSVYTT YQQYEIMFHV STMLPFTPSN RQQLARKRHI GNDIVTIIFQ
EPGAMPFNAQ TMRSHFQHVF IIVRAVDAGT DNVQYSIAVT RFKDVPVFGP PVPANYLFPR
SQEFREFLLT KIINAENAVH KSAKFAQMAA RTRREFMREL AENHCISHSI ESSSVKITSK
ILGNKRKDRP KPKVFLEAFN HGAVVWDVQV LTELENFSLC STIDCYLGIS VDYLVMIERS
SDITLFCTAT HSVIGWTSQG NSLKLYYDHA DVIILRTVDD DDGLILNDII TRLKMVTKGY
ETQEMILRHN PSDVLDFRIQ YEGIVNDVDM YGPSWLAGLR QGSRIVEISK VSVASLTYPK
MLEFLKNANT RVLVIPPLED GSPRRGCEDP HCPAVRGEVT PIIPTDWVPH SGTFPPHLPG
RSPPSYETVM HRQRSGTIAE SLTGSKCKRE LKVQTETGER VSGYSSKSLD ELRSRRLTCY
GDPTVHHDSG FDSTRNSADY QSTTTSSLSS EDRWYQSLKL QPKIRTKTLS SSSSGGSSDL
STEAPPVGQF CKTARADRSS VVNSTASSCC CKDPTTPAAE QISFSGSGAG GGSSPRNLTL
NITNDPCSMI VKANRPSFSA RYDAMKHTKL ANYQAPPLPP KTYKNRTDLP ALPVTESDDS
PSRLHESAFD DDAILINTNS RGLARRQANF LADNGWSISA SKNNQAPRPQ MGDLIKCSSL
VDLATRAIEG IAQVAAVSQR GSPELSSYNL ILQASRRKIV LLEDRVHQLL AELNFERENK
RKLEMEISRL SDENKTLFHE CKAAKEELCH FTEWFCKTVE NPSAYVKEQQ QQQQEQQQRQ
HTKSNNDNNR SSSEAALTSN GGGVECSKSS SG
//
