ID   A0A0V0W0P8_9BILA        Unreviewed;      1746 AA.
AC   A0A0V0W0P8;
DT   16-MAR-2016, integrated into UniProtKB/TrEMBL.
DT   16-MAR-2016, sequence version 1.
DT   27-MAR-2024, entry version 34.
DE   SubName: Full=Abnormal spindle-like microcephaly-associated protein {ECO:0000313|EMBL:KRX69296.1};
GN   Name=ASPM {ECO:0000313|EMBL:KRX69296.1};
GN   ORFNames=T06_2301 {ECO:0000313|EMBL:KRX69296.1};
OS   Trichinella sp. T6.
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Enoplea; Dorylaimia;
OC   Trichinellida; Trichinellidae; Trichinella.
OX   NCBI_TaxID=92179 {ECO:0000313|EMBL:KRX69296.1, ECO:0000313|Proteomes:UP000054673};
RN   [1] {ECO:0000313|EMBL:KRX69296.1, ECO:0000313|Proteomes:UP000054673}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ISS34 {ECO:0000313|EMBL:KRX69296.1};
RA   Korhonen P.K., Edoardo P., Giuseppe L.R., Gasser R.B.;
RT   "Evolution of Trichinella species and genotypes.";
RL   Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KRX69296.1}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; JYDK01000374; KRX69296.1; -; Genomic_DNA.
DR   STRING; 92179.A0A0V0W0P8; -.
DR   Proteomes; UP000054673; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR   GO; GO:0043226; C:organelle; IEA:UniProt.
DR   GO; GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.
DR   CDD; cd21223; CH_ASPM_rpt1; 1.
DR   CDD; cd21224; CH_ASPM_rpt2; 1.
DR   Gene3D; 1.10.418.10; Calponin-like domain; 2.
DR   Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR   InterPro; IPR031549; ASH.
DR   InterPro; IPR001715; CH_dom.
DR   InterPro; IPR036872; CH_dom_sf.
DR   InterPro; IPR013783; Ig-like_fold.
DR   PANTHER; PTHR22706:SF1; ABNORMAL SPINDLE-LIKE MICROCEPHALY-ASSOCIATED PROTEIN ISOFORM X1; 1.
DR   PANTHER; PTHR22706; UNCHARACTERIZED; 1.
DR   Pfam; PF15780; ASH; 1.
DR   Pfam; PF00307; CH; 1.
DR   SUPFAM; SSF47576; Calponin-homology domain, CH-domain; 1.
DR   PROSITE; PS50021; CH; 1.
PE   4: Predicted;
KW   Calmodulin-binding {ECO:0000256|ARBA:ARBA00022860};
KW   Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW   Reference proteome {ECO:0000313|Proteomes:UP000054673}.
FT   DOMAIN          417..548
FT                   /note="Calponin-homology (CH)"
FT                   /evidence="ECO:0000259|PROSITE:PS50021"
FT   REGION          1339..1379
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1348..1371
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1746 AA;  197665 MW;  FAA70D4A26A32339 CRC64;
     MASYALYSPS QSPVRLELTH FSRIAILSFG TVTFGKTAQQ SFLVVNNKQC DQQFFFDFSS
     VNRTDISVDN EAALVPAKGE IECVVKWKPT ETGNFRLSLP LKVTMFPSDE DEYLDAPIRY
     WLRATLVGSC VLPQEILLKQ KKVPLCIQRI PMTSAIKSNV KMGREFESEK LSARPNRIQA
     NHNSQQSVRK DANFKHPFVE HVFTTFLNHL LTQDFITDDS NSEATQVNLK KIFSSSSANV
     SPKAAAQRRV SLKQYAAVQQ LNLLRLSASK AFCEVRAVVY RVCQAVEKGK ILVRREVAIH
     RDQGIMRLIT NLLLSVHPLW LRIGLEVVYS EIIQLDGDCT VRGLINFIRF RMLSDPELLK
     QYGIAHVRSI YKNDYQPAIS KFFLQKFLSL FIFLDFAKQK RLIKQDPCLF NPNSKYKTIR
     DIFVVLNKEI LSGEGNLFKT LAAVGYVPKY KQAWYDEKPL AIENLAVDLR DGLALTRLAA
     MFTENPGLVT NLRGPPISRL QKLHNVQLAL DNFMSANINI GDVDAASIVG GDRDKIMALL
     WRLILHKLEF PDEVVQSPLM PEIISLRRSL RMKNSPEAKK MLNIKLHKKM TISELFICWL
     GCIAAHYGIE VDNLNLSLAD GRVLCCTINY YLPSVLPVDV IKFETSMTTS RESFIPPNEL
     KLNEKANHML FQKSIREIGH VPDFFEFDRL QNLEYTDERV WILCLNSLAT VLFALRREQQ
     AACIIQKAWK TYLRKNCQQA VEMHEYSNVD HYNEHLLVQN EQLKIEEKEN FIVGEMPFDE
     KEQGETCAVA VVDENDKMES GDNLSMEIET LIEFQACCRR KLVLNNFLQQ YKSDSGNEYE
     RSDEEECAKE LSNAQSDQNA DAFDCMTRSE VVQQQNHVYG INVKSNSSLL DANECKVENS
     YAVHDAKDES SLFENNIINL NRNQSVIANE SVCLLETNVA AHKQNELMEP TLDDQKPEFL
     SSSSFLSNLS DMQNALPAVD EVKSISLADI PRIVIEECRS PAETTASSLK FPSFLSSTTS
     ALKPSGSNGR GFAELDAVNE AECPAPFLLI EKLPKFSEML EMFEFRPLEE KRYSPLNFDE
     RQQPLYRSTK VLSLSTENFE CFSDDSGQNL AALLCSDGAS SADVRRETNI TVSSENLLNM
     QMSCNCNYGQ TDQTEADLKP SNDETIAFNE PGNVGAGTDG TDLCMGPTEL LFCSDRCDQN
     FIPLKTDKSV SLMEAVDNLK HLTEIPRESF PANQTSMNNM AEDCLSPPQF GSLTKTPQFD
     STIVGENAAE MNVEFPNLTS AKSPQHQAEY TSLIASFMQS EKMRESVVTF NKRLEYSPIP
     SYLKSSKLHA KCTGPEFATE DADATVQVEP TARSSECGSS PENSEKKLNN TESSNLSDKD
     SEDFVIKEVR DYFETPSLRS IRSAIEVDSK FQMTPYIAEC ERLANRNDSL SFNFLKFSSI
     DFETPIKNRL HNSSSNYSGR PTLTANILNA STRNIFEGIM SAEAKDKNKS NGIIRRIPSL
     TLQQNVMDSI IEQENCLDTE LPVLQNDTLL HKNTNSVQFH FLNAMKKNVV TQHDEISNLL
     KTIVESDRLV CIENAVLRLN EFSKESEDMC KRMVELDAAE KLLALVNRLN RSFNSSIIID
     IVMKCLKQIT SHQSTMKSVT ESVDWFQSLA WQLIYFKDTK PSDTFCNIVA IFCQLSVLDV
     AQAAFQENLQ FVARFERIRK HISKRHEWLV KKYESVSSGS SENLPLKDSA QRLEALKALY
     SCYELL
//