ID A0A0V0W4E9_9BILA Unreviewed; 1137 AA.
AC A0A0V0W4E9;
DT 16-MAR-2016, integrated into UniProtKB/TrEMBL.
DT 16-MAR-2016, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE SubName: Full=Apoptosis-stimulating of p53 protein 2 {ECO:0000313|EMBL:KRX70700.1};
GN Name=TP53BP2 {ECO:0000313|EMBL:KRX70700.1};
GN ORFNames=T06_68 {ECO:0000313|EMBL:KRX70700.1};
OS Trichinella sp. T6.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Enoplea; Dorylaimia;
OC Trichinellida; Trichinellidae; Trichinella.
OX NCBI_TaxID=92179 {ECO:0000313|EMBL:KRX70700.1, ECO:0000313|Proteomes:UP000054673};
RN [1] {ECO:0000313|EMBL:KRX70700.1, ECO:0000313|Proteomes:UP000054673}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ISS34 {ECO:0000313|EMBL:KRX70700.1};
RA Korhonen P.K., Edoardo P., Giuseppe L.R., Gasser R.B.;
RT "Evolution of Trichinella species and genotypes.";
RL Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KRX70700.1}.
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DR EMBL; JYDK01000271; KRX70700.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0V0W4E9; -.
DR STRING; 92179.A0A0V0W4E9; -.
DR Proteomes; UP000054673; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0002039; F:p53 binding; IEA:InterPro.
DR GO; GO:0042981; P:regulation of apoptotic process; IEA:InterPro.
DR Gene3D; 1.25.40.20; Ankyrin repeat-containing domain; 1.
DR InterPro; IPR002110; Ankyrin_rpt.
DR InterPro; IPR036770; Ankyrin_rpt-contain_sf.
DR InterPro; IPR047163; ASPP1/2.
DR InterPro; IPR036028; SH3-like_dom_sf.
DR InterPro; IPR001452; SH3_domain.
DR PANTHER; PTHR24131:SF10; ANKYRIN-REPEAT, SH3-DOMAIN, AND PROLINE-RICH-REGION CONTAINING PROTEIN, ISOFORM B; 1.
DR PANTHER; PTHR24131; APOPTOSIS-STIMULATING OF P53 PROTEIN; 1.
DR Pfam; PF12796; Ank_2; 1.
DR Pfam; PF00018; SH3_1; 1.
DR SMART; SM00248; ANK; 2.
DR SMART; SM00326; SH3; 1.
DR SUPFAM; SSF48403; Ankyrin repeat; 1.
DR SUPFAM; SSF50044; SH3-domain; 1.
DR PROSITE; PS50297; ANK_REP_REGION; 2.
DR PROSITE; PS50088; ANK_REPEAT; 2.
DR PROSITE; PS50002; SH3; 1.
PE 4: Predicted;
KW ANK repeat {ECO:0000256|PROSITE-ProRule:PRU00023};
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000054673};
KW SH3 domain {ECO:0000256|ARBA:ARBA00022443, ECO:0000256|PROSITE-
KW ProRule:PRU00192}.
FT REPEAT 949..981
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 982..1014
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT DOMAIN 1048..1112
FT /note="SH3"
FT /evidence="ECO:0000259|PROSITE:PS50002"
FT REGION 488..537
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 634..656
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 831..908
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1116..1137
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 381..460
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 634..651
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 836..850
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 851..872
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1123..1137
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1137 AA; 125785 MW; 83EA8F3DB4080746 CRC64;
MNGSLWKVEA TSRMLLQANA LKSRCMRRSI KPRSSRLGRS VSIVVLFPFF HTVNWVVEVN
IDAMTGATVV QLICQRPTVS DTAKVVVWWS FGKLQLATAS KFNVDRTGTS NHRGRQLCSA
NGRRKGRAPN FQTVIGQPEM MHVTVVVQLP GKQVAEVPLL PDSTAADVIR QLKLNANLSD
DYFLTADFDG YVELDFYFYC NKTTTTITVH QILKKITTEP ELSNRVKQLL FFVQTLLLCF
MMNSNSICTH VTIEPVLHCN VYKSLRDTNK LFDAEERLYQ LVKKHILGGG RKNDVQFYLR
KKKTITSGLN TSASSSQSDG KNEALPEMYK TNPDFGDLFK MPVSQLRRIA LHRRALIDQN
CNTINEKNRK LNSFLTSSGV DLRLQQKLRQ LEDRLALEEA RFKKLTRLKE ELNNYSLCYK
SLVQQLDLLK MKMRNKKTEV ELADQKVEEL SRLLAKLKLQ RILLAKRAEI SLYDSEIGDL
SCALSLPTTG SGSGADPGPS SGPGPGPDGQ ANSKLSVGSE CSRVQGSRPK AAVEPFKIDT
PDQDIECCST EEAAAAESGS KLDQYVRSKG FRTAFFAMQR ALVEDATGDG RSVELPSDSD
DHEVVVVDGG QPPPSAGPTE PLVKFVHGNA SRRSNVRSEL ADSSQSPPPD LIPASEKSKF
LGQGALASAS DAALGDIVKA ETDKIHLRSD TLRAAKRRSW AEHHANLATS DETEHIRLLL
CRELKKGKTS VNLSWILDQL DSVGAATTST STTNALLSEP MRSSLSPSDE HLNYCRAKVT
SSTTNNDDDT KLTLDSLTAV CCPQISDKLL CDSVEIEKNG KDDKVEVKEQ LLEQQPQEND
DDDDDGGKEE EHEREEITIV VVDEEGPEVE RRQRSGSGTT STNRREAEPK PRRGILQGTS
ARCGDGPVRP RGVHFDPLAL LLDAALEGEL DLVKRCSKQL PNVSVCYEEG ITALHNAICA
GHYDIVRFLV EAGADVNAQD SDGWTPLHCA ASCNNLPIVK FLVENGACIF ASTLSDEETP
AAKCEETEEG FVGCSQFLLG LQQRMGTMNG GIVYAAYSYD PERDDELGFE KDDQLRVLAK
DLDGFSGWWR AFDPKSGREG YVPRNYLSLY PRPSQLRFTT RGGKNDQQEE SRAKTAQ
//
