ID   A0A0V0W909_9BILA        Unreviewed;       819 AA.
AC   A0A0V0W909;
DT   16-MAR-2016, integrated into UniProtKB/TrEMBL.
DT   16-MAR-2016, sequence version 1.
DT   27-MAR-2024, entry version 26.
DE   SubName: Full=Heat shock factor protein 1 {ECO:0000313|EMBL:KRX72121.1};
GN   Name=HSF1 {ECO:0000313|EMBL:KRX72121.1};
GN   ORFNames=T06_14216 {ECO:0000313|EMBL:KRX72121.1};
OS   Trichinella sp. T6.
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Enoplea; Dorylaimia;
OC   Trichinellida; Trichinellidae; Trichinella.
OX   NCBI_TaxID=92179 {ECO:0000313|EMBL:KRX72121.1, ECO:0000313|Proteomes:UP000054673};
RN   [1] {ECO:0000313|EMBL:KRX72121.1, ECO:0000313|Proteomes:UP000054673}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ISS34 {ECO:0000313|EMBL:KRX72121.1};
RA   Korhonen P.K., Edoardo P., Giuseppe L.R., Gasser R.B.;
RT   "Evolution of Trichinella species and genotypes.";
RL   Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC   -!- SIMILARITY: Belongs to the HSF family. {ECO:0000256|ARBA:ARBA00006403,
CC       ECO:0000256|RuleBase:RU004020}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KRX72121.1}.
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DR   EMBL; JYDK01000217; KRX72121.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A0V0W909; -.
DR   Proteomes; UP000054673; Unassembled WGS sequence.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR   InterPro; IPR000232; HSF_DNA-bd.
DR   InterPro; IPR027725; HSF_fam.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   PANTHER; PTHR10015:SF206; HEAT SHOCK FACTOR PROTEIN; 1.
DR   PANTHER; PTHR10015; HEAT SHOCK TRANSCRIPTION FACTOR; 1.
DR   Pfam; PF00447; HSF_DNA-bind; 1.
DR   SMART; SM00415; HSF; 1.
DR   SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
PE   3: Inferred from homology;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW   Reference proteome {ECO:0000313|Proteomes:UP000054673};
KW   Stress response {ECO:0000313|EMBL:KRX72121.1}.
FT   DOMAIN          6..119
FT                   /note="HSF-type DNA-binding"
FT                   /evidence="ECO:0000259|SMART:SM00415"
FT   REGION          223..285
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          321..348
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          544..569
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          658..768
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          145..172
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COMPBIAS        269..285
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        324..339
FT                   /note="Pro residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        658..746
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        753..768
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   819 AA;  90170 MW;  CA392EF2848E1B7B CRC64;
     MSSKFKVSSF LSTLRFILDS EEYNNAVCWD DTGTVFCIKD QEWLVDVILP KFFRHKNFAS
     FIRQLNNCKS SVGIGEVSDG FHKVNAVNIV PPLHANVPCF SHKYFLRGEP SLDVNIRRKC
     YQEKSPPPLT RDEETVTYAD VIRVVMRMNE QLSEITKRVS KLEKEMVDAR KYMPNWCITT
     FLQLLTAASQ KQGTVDLLHL LHMLTQTQYK ANRQNSNGKS VPYVPIVKSQ SPKNGLRVNT
     IGHRKRKQEL NSVESTPPPV VGNDANPSVV AGPTDTTATP SLTTSGEDVS ESFAVCTTPA
     YTDAIMAYNN VENQGKVLLD GGCLDPLPPP PPQQQQHQPQ PQPHPAGDSM ITYPCTWDLP
     GFDDISANFL TDDSDSLMNM EFDYYGGINW RTESADLITF TGGDRVQRVH SASSTSSFSS
     CIDENDKNST LNKTMEFGQW IMSNNNIDGA EENNGNNNSN DNNMLFCPKE LTLAEPEALN
     SQIDDMFFKN LTIPQYSLAI DTNSADHYSL SGNYDFSLTY PTYQEIEFPN SNNLSTVQEV
     SAVSNVQPSG TQPAPSNEPN NGGMENNTVF KPLTNSGSML DDDMYLSNAY NDMLNTPKVD
     ELSHEDLIAE FLLPMTQNDC ETFSNECDLM VSIPQPSFVS EQPMAILQSD VQNLEIPLAN
     NNPLNNGDQG SLNSASLSSM LSTVPSSTTI QSRDESQLPL VGPENGSQKE ENHINVSSSI
     LGRRSSTTSD VPCSDAFQSS SVKSRKRSKS LILKKQQIQT SGKNSGDTAA ANTAAAAAAV
     GDSGGAEKKN DPKAAFCLKM FNLTDAKTGK KITCRVIRR
//