ID   A0A0V0WR30_9BILA        Unreviewed;      1352 AA.
AC   A0A0V0WR30;
DT   16-MAR-2016, integrated into UniProtKB/TrEMBL.
DT   16-MAR-2016, sequence version 1.
DT   27-MAR-2024, entry version 24.
DE   SubName: Full=Tyrosine-protein phosphatase non-receptor type 23 {ECO:0000313|EMBL:KRX78196.1};
DE   Flags: Fragment;
GN   Name=PTPN23 {ECO:0000313|EMBL:KRX78196.1};
GN   ORFNames=T06_5182 {ECO:0000313|EMBL:KRX78196.1};
OS   Trichinella sp. T6.
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Enoplea; Dorylaimia;
OC   Trichinellida; Trichinellidae; Trichinella.
OX   NCBI_TaxID=92179 {ECO:0000313|EMBL:KRX78196.1, ECO:0000313|Proteomes:UP000054673};
RN   [1] {ECO:0000313|EMBL:KRX78196.1, ECO:0000313|Proteomes:UP000054673}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ISS34 {ECO:0000313|EMBL:KRX78196.1};
RA   Korhonen P.K., Edoardo P., Giuseppe L.R., Gasser R.B.;
RT   "Evolution of Trichinella species and genotypes.";
RL   Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KRX78196.1}.
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DR   EMBL; JYDK01000070; KRX78196.1; -; Genomic_DNA.
DR   Proteomes; UP000054673; Unassembled WGS sequence.
DR   GO; GO:0005768; C:endosome; IEA:UniProtKB-SubCell.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0004725; F:protein tyrosine phosphatase activity; IEA:InterPro.
DR   GO; GO:0071985; P:multivesicular body sorting pathway; IEA:InterPro.
DR   Gene3D; 1.25.40.280; alix/aip1 like domains; 1.
DR   Gene3D; 3.90.190.10; Protein tyrosine phosphatase superfamily; 1.
DR   InterPro; IPR025304; ALIX_V_dom.
DR   InterPro; IPR045251; BRO1-like.
DR   InterPro; IPR004328; BRO1_dom.
DR   InterPro; IPR038499; BRO1_sf.
DR   InterPro; IPR029021; Prot-tyrosine_phosphatase-like.
DR   InterPro; IPR000242; PTP_cat.
DR   InterPro; IPR003595; Tyr_Pase_cat.
DR   PANTHER; PTHR23030; PCD6 INTERACTING PROTEIN-RELATED; 1.
DR   PANTHER; PTHR23030:SF30; TYROSINE-PROTEIN PHOSPHATASE NON-RECEPTOR TYPE 23; 1.
DR   Pfam; PF13949; ALIX_LYPXL_bnd; 1.
DR   Pfam; PF03097; BRO1; 1.
DR   Pfam; PF00102; Y_phosphatase; 1.
DR   SMART; SM01041; BRO1; 1.
DR   SMART; SM00194; PTPc; 1.
DR   SMART; SM00404; PTPc_motif; 1.
DR   SUPFAM; SSF52799; (Phosphotyrosine protein) phosphatases II; 1.
DR   PROSITE; PS51180; BRO1; 1.
DR   PROSITE; PS50055; TYR_PHOSPHATASE_PTP; 1.
PE   4: Predicted;
KW   Membrane {ECO:0000256|SAM:Phobius}; Receptor {ECO:0000313|EMBL:KRX78196.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000054673};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        1292..1318
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        1330..1349
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          29..657
FT                   /note="BRO1"
FT                   /evidence="ECO:0000259|PROSITE:PS51180"
FT   DOMAIN          868..1126
FT                   /note="Tyrosine-protein phosphatase"
FT                   /evidence="ECO:0000259|PROSITE:PS50055"
FT   REGION          754..779
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          1137..1165
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   NON_TER         1352
FT                   /evidence="ECO:0000313|EMBL:KRX78196.1"
SQ   SEQUENCE   1352 AA;  155877 MW;  15B86A1C3F374BDF CRC64;
     MELNIEQSIH SRLKLMEIRP RSFPDDYQPL SRVPFAAMRA RTCKNSNRTT ANMKNLMSSS
     FQADFDKYIE SMLISDTCDA GTSIVVQSTL REIRRSAGYY IRLMFLKEKL NSISEKERQN
     LLVDSFRNSP SLAINQIDFE MAGVLHNVAS SYSFLAARLI RATSMDMQLA ATFFQFASGI
     FEQLRGKHSE MARYNNDFST TVISFRYKFM LAQAQECMVE RSMLDGIDEK YISEFVMQVI
     QDYNACDTSL DAVQAVEAFP ANEVTILRQL IDFKRTYFTA LLHLSLSNVA FKEGRRDEVI
     ARLRLAKEGL SGIESKFAQL PEQFLPVTDR LLRVIDRKLS STRYYGISEK DIARVELNPC
     MAVLAVGPMS LFEQQETTEI NTNNSTMYVQ RVASVFRNIR AVALQPYITH HDELNRQFKS
     LFRSTQLEQV YMYVDRKVPE DIAYWSNLLK ANPQLVERLN GILNHLHSVR SSARTKLIDV
     VKRLKDFRGN IKKHHRKSNF KVVINYLNGT EKMVAKCQDV FRQAEETGDQ LSNAHKSVML
     ILETLQKSLD CVAETIFADL YDPCSTEVGR QMNELRTTAL SVFLKRMSVI KGVRKAMTND
     DPVEKLNMLD EIGFQGRFFD KELAKYNGVC QFLRTSFATH EKIFKQISSL ERNFKPIREH
     ALRCNESITR RFKSMVECCK SIKTMESKVG EGERFYARLH FLLNESLRRI EQLEIGATCG
     YKNIKADDTP CCISITDCLR SDIPLLIDDN GRGFGTMTNN ETESGTTGDG ESTTSEHESI
     AGRCTYDVEM KDTRRGSSSS KSLQQQRRGG EKVCSFEVLK QKLCCKGVER MVTLKPKLDL
     DKLKNYFENL KELVDSLETV TSNGMTKLDL EWQEVQRKCN EEAQKHDISE AKKFTSMNRN
     STMLPYDDNR ILVMTPKQDY VNASLIGKLC EYGPAFYIAQ IPTKPVVASF WCMLFENKIE
     LLCMIFDSRD CNAKNFMPRE NAKLKTAQFS ISIASKEDFG AWTESTIVME ELRDPKHSYS
     FKCLHFDGWQ NKSELIDVDG FAKFVLQVRR YFLLQKQNRS SVVAMSLYGS SRSGIFSICL
     SACCEIMAGK PLPLIDEMPE RLCMWRNNCI TSKQDLYTCY MVVLTILKNI CESQENGDFD
     EQDENEQEEY NNNSDESAIE YDDDDGKEFN EELRQLEEKM SKYTFTDPLD LQFGGPSCSG
     VGNGQQAAKV NNNENKQHRC CYNVIDMKNQ TKQSMTQLLH LVNAESMNNN FFTDQAKPAR
     ASCFDLLCLM TNTMIQRMRF IFHTNYVRYS SYIIYLLCLS IHSFIIFIIL LSSLYYLTSH
     NDHYCDYYHY IIRVCNTYTY IYLFIYLFGH FE
//