ID A0A0V0WRX1_9BILA Unreviewed; 1152 AA.
AC A0A0V0WRX1;
DT 16-MAR-2016, integrated into UniProtKB/TrEMBL.
DT 16-MAR-2016, sequence version 1.
DT 24-JAN-2024, entry version 32.
DE SubName: Full=Transcription initiation factor TFIID subunit 5 {ECO:0000313|EMBL:KRX78540.1};
GN Name=IK {ECO:0000313|EMBL:KRX78540.1};
GN ORFNames=T06_372 {ECO:0000313|EMBL:KRX78540.1};
OS Trichinella sp. T6.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Enoplea; Dorylaimia;
OC Trichinellida; Trichinellidae; Trichinella.
OX NCBI_TaxID=92179 {ECO:0000313|EMBL:KRX78540.1, ECO:0000313|Proteomes:UP000054673};
RN [1] {ECO:0000313|EMBL:KRX78540.1, ECO:0000313|Proteomes:UP000054673}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ISS34 {ECO:0000313|EMBL:KRX78540.1};
RA Korhonen P.K., Edoardo P., Giuseppe L.R., Gasser R.B.;
RT "Evolution of Trichinella species and genotypes.";
RL Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the RED family. {ECO:0000256|ARBA:ARBA00006660}.
CC -!- SIMILARITY: Belongs to the WD repeat TAF5 family.
CC {ECO:0000256|ARBA:ARBA00009435}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KRX78540.1}.
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DR EMBL; JYDK01000065; KRX78540.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0V0WRX1; -.
DR STRING; 92179.A0A0V0WRX1; -.
DR Proteomes; UP000054673; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW.
DR CDD; cd00200; WD40; 1.
DR Gene3D; 1.25.40.500; TFIID subunit TAF5, NTD2 domain; 1.
DR Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 2.
DR InterPro; IPR039896; Red-like.
DR InterPro; IPR012492; RED_C.
DR InterPro; IPR012916; RED_N.
DR InterPro; IPR007582; TFIID_NTD2.
DR InterPro; IPR037264; TFIID_NTD2_sf.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR InterPro; IPR019775; WD40_repeat_CS.
DR InterPro; IPR036322; WD40_repeat_dom_sf.
DR InterPro; IPR001680; WD40_rpt.
DR PANTHER; PTHR12765:SF5; PROTEIN RED; 1.
DR PANTHER; PTHR12765; RED PROTEIN IK FACTOR CYTOKINE IK; 1.
DR Pfam; PF07807; RED_C; 1.
DR Pfam; PF07808; RED_N; 1.
DR Pfam; PF04494; TFIID_NTD2; 1.
DR Pfam; PF00400; WD40; 3.
DR SMART; SM00320; WD40; 5.
DR SUPFAM; SSF160897; Taf5 N-terminal domain-like; 1.
DR SUPFAM; SSF50978; WD40 repeat-like; 1.
DR PROSITE; PS00678; WD_REPEATS_1; 2.
DR PROSITE; PS50082; WD_REPEATS_2; 3.
DR PROSITE; PS50294; WD_REPEATS_REGION; 3.
PE 3: Inferred from homology;
KW Initiation factor {ECO:0000313|EMBL:KRX78540.1};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Protein biosynthesis {ECO:0000313|EMBL:KRX78540.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000054673};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW WD repeat {ECO:0000256|ARBA:ARBA00022574, ECO:0000256|PROSITE-
KW ProRule:PRU00221}.
FT DOMAIN 84..299
FT /note="RED-like N-terminal"
FT /evidence="ECO:0000259|Pfam:PF07808"
FT DOMAIN 444..523
FT /note="Protein RED C-terminal"
FT /evidence="ECO:0000259|Pfam:PF07807"
FT DOMAIN 632..738
FT /note="TFIID subunit TAF5 NTD2"
FT /evidence="ECO:0000259|Pfam:PF04494"
FT REPEAT 909..950
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 994..1035
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 1036..1069
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REGION 1..29
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 325..382
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 397..417
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 502..522
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..26
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 329..369
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 397..413
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 502..521
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1152 AA; 130005 MW; A01DCBE793C9D219 CRC64;
MNNKEASSGN VKAEIVDSSS AGQPLTNDDF RKLLMTPRPV SQSSLRQAQL MGRAKVSSRS
QKDEKKKKLI NIIKTQDGPI RGSSHEKNEL NEILKHYRDR AKERRECELK EYQQEIDMLA
TSGYRAVAPT LKAAVDMTAR RKQIIEESKY LGGDMEHTHL VKGLDYALLQ KVRSEISTRE
KLTPSVEKTT TAYTVEDSLT PEVESSIKSS TVKNIYQLLF KKEAKKVNEM FIPYRMAYIV
ELDEENAESD IPTTLIRSKH ECASQEVVSA ASIDDMIIQK LGKVLSYLRA DNRKKKKEKG
KGKEDESVAN QDIYEDIGEY VPALSRQPKV KSEAEEHGKK LHGDYDRNSK LEHEGSRLKV
IHKEENNDST KSWPVANDEQ LHKHSSGRYF SDVSDAKDQE VNAMSRKSDR RKGTTQTTAT
NFVEPKSVKP DALKLDTGSS VDSYAECYPS SMAFYDAAGD SDDEADYSKM DLGNKKGLVR
RWDFDTEQEA AFQYGVKMND GRRTRKLPGT RSEKDDKAKI NPNYPDTFQE KRIFRCSYFA
VLLRNALFVA HVTVRTANGT IDLQNIADVD DQMIVKCLNF FRVEGFFDAE RTFVRELRNI
GRSAAVDAYL QRVGCTVNDN QLATVKSWNH WIEEYDYFFQ YTKSKVDALC ELSLLNFPLF
TQLYIQLLKA GKMKLASRFY DEFHSVQKES MQEYTKQLGW IHSSEQLADD WLIQILEEHN
FVLCLCLACK SALNELMEKL PTIKDIIESK IQIECHGEVC RSEEQVEQIS GYLLGEAPRQ
LNQIPVLASC FDHGGNDVPS WDRIPFPISR DEVILTNSDE IKKICLNDAR PSVCFYTVLN
PRVAVSSMVV SSDSTLLCVG NLDCSVEVFS LSKDLMEMLK PASQLLHTED DLDPSSIFDS
SSAQSKFSLF GHSSPVYGVS FNRSGEFVLS CCLNGEIILW NLLTRTRIAD YRMQMLKGLD
VKFGPYDGYF VVSDYHSGGA LMWSMECETP VRAFIGHLST VNCVAFHPNS NYVATGSNDR
TVRLWDLLDG KCVRLFTGHQ DAIQSLYFSD DGHILASGGL SGQVMLWDVA MAARLEGFKH
SDRGVSGLAI SRDGSTVAWG GADQKVMLRS IGDNSKSEMP CVLTYRTKSA PVQHLHFTQE
NELIGFGGFC RD
//
