ID A0A0V0WZ30_9BILA Unreviewed; 803 AA.
AC A0A0V0WZ30;
DT 16-MAR-2016, integrated into UniProtKB/TrEMBL.
DT 16-MAR-2016, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE RecName: Full=U4/U6 small nuclear ribonucleoprotein Prp31 {ECO:0000256|ARBA:ARBA00013538};
DE AltName: Full=Pre-mRNA-processing factor 31 {ECO:0000256|ARBA:ARBA00030766};
GN Name=prpf31 {ECO:0000313|EMBL:KRX80957.1};
GN ORFNames=T06_12559 {ECO:0000313|EMBL:KRX80957.1};
OS Trichinella sp. T6.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Enoplea; Dorylaimia;
OC Trichinellida; Trichinellidae; Trichinella.
OX NCBI_TaxID=92179 {ECO:0000313|EMBL:KRX80957.1, ECO:0000313|Proteomes:UP000054673};
RN [1] {ECO:0000313|EMBL:KRX80957.1, ECO:0000313|Proteomes:UP000054673}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ISS34 {ECO:0000313|EMBL:KRX80957.1};
RA Korhonen P.K., Edoardo P., Giuseppe L.R., Gasser R.B.;
RT "Evolution of Trichinella species and genotypes.";
RL Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the PRP31 family.
CC {ECO:0000256|ARBA:ARBA00005572}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KRX80957.1}.
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DR EMBL; JYDK01000036; KRX80957.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0V0WZ30; -.
DR STRING; 92179.A0A0V0WZ30; -.
DR Proteomes; UP000054673; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0005681; C:spliceosomal complex; IEA:UniProtKB-KW.
DR GO; GO:0046540; C:U4/U6 x U5 tri-snRNP complex; IEA:InterPro.
DR GO; GO:0008081; F:phosphoric diester hydrolase activity; IEA:InterPro.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR GO; GO:0006629; P:lipid metabolic process; IEA:InterPro.
DR GO; GO:0000244; P:spliceosomal tri-snRNP complex assembly; IEA:InterPro.
DR Gene3D; 1.10.287.4070; -; 1.
DR Gene3D; 1.10.246.90; Nop domain; 1.
DR Gene3D; 3.20.20.190; Phosphatidylinositol (PI) phosphodiesterase; 1.
DR InterPro; IPR030395; GP_PDE_dom.
DR InterPro; IPR042239; Nop_C.
DR InterPro; IPR002687; Nop_dom.
DR InterPro; IPR036070; Nop_dom_sf.
DR InterPro; IPR012976; NOSIC.
DR InterPro; IPR017946; PLC-like_Pdiesterase_TIM-brl.
DR InterPro; IPR027105; Prp31.
DR InterPro; IPR019175; Prp31_C.
DR PANTHER; PTHR13904; PRE-MRNA SPLICING FACTOR PRP31; 1.
DR PANTHER; PTHR13904:SF0; U4_U6 SMALL NUCLEAR RIBONUCLEOPROTEIN PRP31; 1.
DR Pfam; PF03009; GDPD; 1.
DR Pfam; PF01798; Nop; 1.
DR Pfam; PF09785; Prp31_C; 1.
DR SMART; SM00931; NOSIC; 1.
DR SUPFAM; SSF89124; Nop domain; 1.
DR SUPFAM; SSF51695; PLC-like phosphodiesterases; 1.
DR PROSITE; PS51704; GP_PDE; 1.
DR PROSITE; PS51358; NOP; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|SAM:Phobius};
KW mRNA processing {ECO:0000256|ARBA:ARBA00022664};
KW mRNA splicing {ECO:0000256|ARBA:ARBA00023187};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000054673};
KW Ribonucleoprotein {ECO:0000256|ARBA:ARBA00023274,
KW ECO:0000313|EMBL:KRX80957.1}; RNA-binding {ECO:0000256|ARBA:ARBA00022884};
KW Spliceosome {ECO:0000256|ARBA:ARBA00022728};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 6..23
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 39..287
FT /note="GP-PDE"
FT /evidence="ECO:0000259|PROSITE:PS51704"
FT DOMAIN 512..630
FT /note="Nop"
FT /evidence="ECO:0000259|PROSITE:PS51358"
FT REGION 628..654
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 694..714
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 803 AA; 90164 MW; AF5DB595712E61F9 CRC64;
MDAFWLVVAT TVIIYILFCA YAIQNPPKYV MMKAPAFKAK IIAHRGGAGE HVENTLSAML
LAAEKKVDML ELDVHITKDE QVVVCHDDHL LRVSGVDNYI SKLNYNELPF LKNNIPLDEH
SEVLGGSTQN MMDRRIPLLE EILKQTYPIP VNIDIKINND KLIEKTAEIV SISKRENSVA
WGNFDEKIVR KLHKANRNVN LICSTRTTIR LLQQIPSCCI KNFSCSRLVR HEYNTLLLNP
VLFKHLKKRG MQIFLWVLNT PEEFEHAFRV GTDGIITDYP TLLQNAPGLF IYFSSRHIPE
NLVMSLAEEL LADLEEGDDD DYNVAEEAAE GEEKETRTRS IYNRVTAVAH LLHSDHFQGI
MQRIADRMEN SHLTNISGPV ESHPEYLLIV DANGLAAEID NEIAVVHKFV RDKYAKRFPE
LESLVQMPME YVACVKELGN DILDKAKHNE QLQNILLPST VIVISVTAST TQGECLSDEE
LAIVMEGCEM AIQLNDAKLK IYQFVESRMH CIAPNLSVIL GPEIAAKLMG TAGGITQLSK
IPACNVLILG SQKRTLSGFS STTILPHTGY IYYTPLVQSL PVDLRRKAAR LVAAKCTLAA
RIDSVHSHSD GSVGLKLAEE VRSKFEKWQE PPPKKLIKPL SKPLDQASKK RGGRRIRKMK
ERLGLTELRR KANRMNFGQI EEDILQEHMG FSLGQAKTGG PGGRLRTPQV DQKSRARMSK
TLQRNMQKQQ STFGSVTSVR RQLAGTISTV TFTPVQGLEI VNPQAAEKDK SAEAASAKYF
REDAEFIKVE TPIPGHHHNH QSK
//
