ID A0A0V0X602_9BILA Unreviewed; 1907 AA.
AC A0A0V0X602;
DT 16-MAR-2016, integrated into UniProtKB/TrEMBL.
DT 16-MAR-2016, sequence version 1.
DT 27-MAR-2024, entry version 35.
DE SubName: Full=Afadin {ECO:0000313|EMBL:KRX83472.1};
GN Name=MARCH1 {ECO:0000313|EMBL:KRX83472.1};
GN ORFNames=T06_2897 {ECO:0000313|EMBL:KRX83472.1};
OS Trichinella sp. T6.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Enoplea; Dorylaimia;
OC Trichinellida; Trichinellidae; Trichinella.
OX NCBI_TaxID=92179 {ECO:0000313|EMBL:KRX83472.1, ECO:0000313|Proteomes:UP000054673};
RN [1] {ECO:0000313|EMBL:KRX83472.1, ECO:0000313|Proteomes:UP000054673}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ISS34 {ECO:0000313|EMBL:KRX83472.1};
RA Korhonen P.K., Edoardo P., Giuseppe L.R., Gasser R.B.;
RT "Evolution of Trichinella species and genotypes.";
RL Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KRX83472.1}.
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DR EMBL; JYDK01000013; KRX83472.1; -; Genomic_DNA.
DR STRING; 92179.A0A0V0X602; -.
DR Proteomes; UP000054673; Unassembled WGS sequence.
DR GO; GO:0005911; C:cell-cell junction; IEA:InterPro.
DR GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR CDD; cd22711; FHA_AFDN; 1.
DR CDD; cd00992; PDZ_signaling; 1.
DR CDD; cd01782; RA1_Afadin; 1.
DR Gene3D; 2.30.42.10; -; 1.
DR Gene3D; 2.60.200.20; -; 1.
DR InterPro; IPR028842; Afadin.
DR InterPro; IPR002710; Dilute_dom.
DR InterPro; IPR001478; PDZ.
DR InterPro; IPR036034; PDZ_sf.
DR InterPro; IPR000159; RA_dom.
DR InterPro; IPR008984; SMAD_FHA_dom_sf.
DR InterPro; IPR029071; Ubiquitin-like_domsf.
DR PANTHER; PTHR10398; AFADIN; 1.
DR PANTHER; PTHR10398:SF2; AFADIN; 1.
DR Pfam; PF01843; DIL; 1.
DR Pfam; PF00595; PDZ; 1.
DR Pfam; PF00788; RA; 2.
DR SMART; SM01132; DIL; 1.
DR SMART; SM00228; PDZ; 1.
DR SMART; SM00314; RA; 2.
DR SUPFAM; SSF50156; PDZ domain-like; 1.
DR SUPFAM; SSF49879; SMAD/FHA domain; 1.
DR SUPFAM; SSF54236; Ubiquitin-like; 2.
DR PROSITE; PS51126; DILUTE; 1.
DR PROSITE; PS50106; PDZ; 1.
DR PROSITE; PS50200; RA; 2.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000054673}.
FT DOMAIN 42..136
FT /note="Ras-associating"
FT /evidence="ECO:0000259|PROSITE:PS50200"
FT DOMAIN 223..319
FT /note="Ras-associating"
FT /evidence="ECO:0000259|PROSITE:PS50200"
FT DOMAIN 718..947
FT /note="Dilute"
FT /evidence="ECO:0000259|PROSITE:PS51126"
FT DOMAIN 1099..1184
FT /note="PDZ"
FT /evidence="ECO:0000259|PROSITE:PS50106"
FT REGION 1373..1397
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1445..1471
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1562..1581
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1565..1581
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1907 AA; 214737 MW; CB382C3B4EB2BB0E CRC64;
MEYSNLDEKH AMRVQLTKLI EDWNASRLDL FALCEPNEEL EFHGVMRFYF QDSGQKMATK
CIRVSSTATT RAVIEALIEK FHADLRLLST PSYSLWEVHE NGEKRKLLAD EKPLLVQLNW
HKDDREGRFL LQMDKADQQP NMLPVEAIEN GTTSMRRKLS KRESKKLEKQ QKMNQIREAE
DVTKLLYSAV PNTNFTRTIS NPEIVMKKRR ERKLEQKLKD LGEGGSLKIY GEELSETKPY
VTLLLSLRDR ADKVVRETLE KYGLDRHCSD EFCLVQLCTN EQGDIFERIL DKDDCPLLIL
AQEGNESNCV TFHVRRKPST LSRSTVGFTG AAGRIADGPR PPAQPEQHNN KLDTLPYLLE
INPDGSEPAG ASRIFVIRPN VTEVGSDRTF TKPGVQALCV NKREILFYLK MFIHHHLYGP
HVHPRHCVIA FMDGLTTLTP CDATAEITVD DVSITETTIL KQNNLIRIGG IHLFRFYETG
GENMNSVHAE AFMKPNNHNS INDNNASYGS VIGSGRNKFY SHFTKADPLR CLIMTPKIIR
CALFKAAKGK VVIHSGGDLL TSGILRILLQ QGDFCFAVVF CFVFIDLANC NSTVCVGDEM
KLWTLFSAAD SNINDMERIL HPARGMSPRA QELATNAKFL ARTSSNLEDV IPALFEFSNN
VEDDLLKAII CELIPSNVSF KLTPAYMLYM CCRYRIVRHL DVGRSWNACS SSLNCFLTKT
SRMINETVQA HCQDAGALAF WMSNLAEALN FLKLDVDLAA CSSPEPQGSM ADLIQKAFDH
LTVCLKQDLH TAMPPILDPQ ALDQAATEPC LHVLNCVMNL LRVNRVNAAL TIQLFSQLFH
YINMYLFNWL ISSEGSVYCC RRWGIKLRSR LSYVLAWAEK QGLELAAECR LVRILEASQL
LQLDFKRGFT KLNSLQTASL LERYIPEADE PPLDRETVTA LIQFAEREVD RCQSYEHVPL
QLEEEIDLLL PFLIPDDGYS PEMVRGIPAG LQDFANSLAQ RGFGQLLIQP TSSGSWAVHF
SGDSLFDIPQ YHKMHNSNLT SMMMNNSGDV AGHNRQAFTG TRLIEKMGAI PTPLLLLQKR
QNSVNRSSES DTTGPHLMFV SFEKGSNGIG LSIVQAQGNE DQMPGIYVKK VVPGSAAAQD
GRLQAGDQLL KVNGQSLIGV SQECAAQMMS QSGQVVNFEV AKGAALYNGL AQWIYQLSPD
NRYQQQQQQQ QMHPVANSPI IYSPHTNNAS PVRRHVVGET VPSQPASNRT NNGNNYRYST
SDIHHGRRLV KQFQQPPVSN SRFHSTIGQQ MGRSGRSLSA SSLLHEMQME RSLGRGRTDS
VPSSPAFSSR SDRVFHNAKM IPNPTSGVTK HHQTSADGTA IAAGYNPIVR QSVGSRRSAG
SQQIYSHETQ SSPQQQHTLN KNYANYNQVV DTTRQSPRSN LPQPQTADFY GSAQQKQTIA
NGGVGVSSSI QQLPPPAQLS QRPPSRSDLY SAPIMMSDQN SKSRLIPCLE NGTQSNPYPA
DFLEPNEMDR EDLEQQVDSE MEKLMRDELA RLQSKSSLTA AEQRRYRALR YELEFRRRLS
NSSHADDNHY QQIYDPNQQQ QHNNYSKSYE LDMSHRGNSF NVPVQSASGN SDTSALNEAA
CARRQQQRDL YFEDAERRYQ QIAAKEWNRT QQKDSPITGG RLGQAAVKNV ITAEPVANGR
GAWHNLDSKM LQTESQMKNL SVTANGGNRM MDSNLKASSS LAENTTNIRK MTPVTTSRPQ
VQFDTAPPAV YHVETLDDDQ RFLDFVTSTS ETRPVSNELE QMITSSDGSS TSEQHHHFPT
VHAAESRYVY QMHEETPRVI GNQEVYKDPR QERLKHLKPN NSQVEGEKLS FRDKMKLFAK
EINESTPKPA TIEEFLRIHQ NCTDHEIVEY TRERWSTKYA NYNFSVL
//
