ID A0A0V0X9L6_9BILA Unreviewed; 1574 AA.
AC A0A0V0X9L6;
DT 16-MAR-2016, integrated into UniProtKB/TrEMBL.
DT 16-MAR-2016, sequence version 1.
DT 24-JAN-2024, entry version 19.
DE SubName: Full=GTPase-activating protein pac-1 {ECO:0000313|EMBL:KRX84584.1};
DE Flags: Fragment;
GN Name=arhgap21 {ECO:0000313|EMBL:KRX84584.1};
GN ORFNames=T06_15913 {ECO:0000313|EMBL:KRX84584.1};
OS Trichinella sp. T6.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Enoplea; Dorylaimia;
OC Trichinellida; Trichinellidae; Trichinella.
OX NCBI_TaxID=92179 {ECO:0000313|EMBL:KRX84584.1, ECO:0000313|Proteomes:UP000054673};
RN [1] {ECO:0000313|EMBL:KRX84584.1, ECO:0000313|Proteomes:UP000054673}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ISS34 {ECO:0000313|EMBL:KRX84584.1};
RA Korhonen P.K., Edoardo P., Giuseppe L.R., Gasser R.B.;
RT "Evolution of Trichinella species and genotypes.";
RL Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KRX84584.1}.
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DR EMBL; JYDK01000005; KRX84584.1; -; Genomic_DNA.
DR Proteomes; UP000054673; Unassembled WGS sequence.
DR GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR CDD; cd01253; PH_ARHGAP21-like; 1.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR Gene3D; 1.10.555.10; Rho GTPase activation protein; 1.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR001849; PH_domain.
DR InterPro; IPR008936; Rho_GTPase_activation_prot.
DR InterPro; IPR000198; RhoGAP_dom.
DR PANTHER; PTHR23175; PDZ DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR23175:SF23; PDZ DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF00169; PH; 1.
DR Pfam; PF00620; RhoGAP; 1.
DR SMART; SM00233; PH; 1.
DR SMART; SM00324; RhoGAP; 1.
DR SUPFAM; SSF48350; GTPase activation domain, GAP; 1.
DR SUPFAM; SSF50729; PH domain-like; 1.
DR PROSITE; PS50003; PH_DOMAIN; 1.
DR PROSITE; PS50238; RHOGAP; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000054673}.
FT DOMAIN 552..674
FT /note="PH"
FT /evidence="ECO:0000259|PROSITE:PS50003"
FT DOMAIN 814..1006
FT /note="Rho-GAP"
FT /evidence="ECO:0000259|PROSITE:PS50238"
FT REGION 62..89
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 387..418
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 726..752
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1413..1435
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1460..1485
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1531..1574
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1553..1567
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:KRX84584.1"
SQ SEQUENCE 1574 AA; 173649 MW; 9DCC06BEF416217E CRC64;
LVYMMTENLN SCTLNNEEQL LNVEKKEKWE NSSTGYCEEE HDNNDKAVGR LDLASWKRTN
DVSVGDAGKK QEEEEEEVEE DAAAAVDATK DDDSLNGSLK LATWKRDLAS RSNSGLVSSR
TVPWCLRRGS VKTGVVSQIV EALRENRKLD ENCCCSSSSS SSAQLGCCYA TTSAKDSKYY
YYANRRFNNS TPASTVAASD SCLVRTLISL YERGTVDRVG PLKLYHAQMY KRELNRITSH
NLGQVLRKAK RFDQLLSGPR RHSLDSNQFF DSLVDNNYQN PATTTTTTTD VKGLIIDNQG
QIRCRAMSTF LDESFPTNRP DVLTCRLRRQ QSFIRAVTGN KLLTSDASHL GVNFELITPV
LLIYWSIGIV FVDSGLADID TINEYTDQSS SSVNGDYPAD GKSKKQSTNR SMPNGNILSS
QAIRNGRRHS TLKLMDALGK VEVMEKSLLA NGNAAIPCSS RTTVPCSARI PVPPGKDQIL
SPPFVRYRQQ GNREKRITHF INFYNSCQDQ VDNFTSEACS PSPSCSSSFS DSSCAKPTTL
SPCSDSTSRS DTVYREGILY HKQVAVENGR RAHDRSWQLY WAFLIDHRMY LCPEKPMLAV
PPTALSFDKV ANFVREKAAL LIDVRSCIAD IAYSHLKRKN VFRCITVNQS EHLFQAMDEK
DMIGWIAALQ SCAVIEETET VSPSSLALII KHYERQSHSL SPSVKLKKPT TLHRVVTAAK
ERNTAAATNA SLMDDARHDQ QTATDLNRDE ASTVVASSSS SSSFGQLAHS KLEKGEATLK
KVKKWCKTRK AAAGPAAVVS SQVNNPKVNA VFGINLEECV TTGETDFVPL IVQLCVKVVE
AYGLDTVGVY RIPGNTAAVN TLSANLDQGF EFVEFDDIRW RDVNVVSSLL KAFFRKLPDP
LLTSALYRDF IEANRIESLE SRLKVFRELI FKLPKHNFET LKFLLQHLKR VVAHSSVNKM
EVKNLALMFG PSLVRPSGEN MVTMVTHMSD QCKIVELLLS HSDWIFGSDW SASLDNQSEL
TKSLDHSSSN VGELLNLIHH SEKDLDKVKE NLARNLQNVK MVKSGCLAPS SIAQAIQQPQ
QCFTTADYDE RNIDEEVARA ERLHSLSVEC CTPSLLNSRR LSAGVGDPLT ISARSSTTNE
LIQAAEDYRK SREEQIYTAR RIFIAGTSAV DSVHNSPPVD SVAKIDGLAR HCRHLNVNPN
SLDFLSPETR EKIKQFQRGH PLWSSSSARS GNNILASLST TGPQFSSNND NGNEVNLRQH
NDELIPYSES DVRKKNIDDM LMSRSCQARL AYSTNSPKIN TPGATVIATT DRAFSNSNNN
NSTTYQHGAS TLAKESYPAT SFICASSISS SGMHDQSKLV ESNLSKPISS PAADSSSSSS
AFLRRHVIMR RPAQMESVAT NREQNKNVKN LPISPSTAII NNTTTTPSSS SCSSRSTILR
NYGQSSFDSA MPAKFSHLLK LNNRKSSSPQ AGGGKRRDAR RHTLGNVDCG GIVGVKLSST
PSTITASTRW SIEAVTGAQG GVGAGMMASV ESKARQDDDH ALKQRCLKRR SVRRSNPNLS
SPPLNFDPAL QVHS
//
