ID A0A0V0XAQ5_9BILA Unreviewed; 850 AA.
AC A0A0V0XAQ5;
DT 16-MAR-2016, integrated into UniProtKB/TrEMBL.
DT 16-MAR-2016, sequence version 1.
DT 22-FEB-2023, entry version 18.
DE SubName: Full=Breast cancer anti-estrogen resistance protein 3 {ECO:0000313|EMBL:KRX85110.1};
DE Flags: Fragment;
GN Name=BCAR3 {ECO:0000313|EMBL:KRX85110.1};
GN ORFNames=T06_8837 {ECO:0000313|EMBL:KRX85110.1};
OS Trichinella sp. T6.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Enoplea; Dorylaimia;
OC Trichinellida; Trichinellidae; Trichinella.
OX NCBI_TaxID=92179 {ECO:0000313|EMBL:KRX85110.1, ECO:0000313|Proteomes:UP000054673};
RN [1] {ECO:0000313|EMBL:KRX85110.1, ECO:0000313|Proteomes:UP000054673}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ISS34 {ECO:0000313|EMBL:KRX85110.1};
RA Korhonen P.K., Edoardo P., Giuseppe L.R., Gasser R.B.;
RT "Evolution of Trichinella species and genotypes.";
RL Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KRX85110.1}.
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DR EMBL; JYDK01000003; KRX85110.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0V0XAQ5; -.
DR Proteomes; UP000054673; Unassembled WGS sequence.
DR GO; GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:InterPro.
DR GO; GO:0001784; F:phosphotyrosine residue binding; IEA:InterPro.
DR GO; GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
DR CDD; cd10337; SH2_BCAR3; 1.
DR Gene3D; 1.10.840.10; Ras guanine-nucleotide exchange factors catalytic domain; 1.
DR Gene3D; 3.30.505.10; SH2 domain; 1.
DR InterPro; IPR023578; Ras_GEF_dom_sf.
DR InterPro; IPR001895; RASGEF_cat_dom.
DR InterPro; IPR036964; RASGEF_cat_dom_sf.
DR InterPro; IPR000980; SH2.
DR InterPro; IPR036860; SH2_dom_sf.
DR InterPro; IPR044102; SH2_SHEP1/BCAR3/NSP1.
DR PANTHER; PTHR14247; BREAST CANCER ANTI-ESTROGEN RESISTANCE PROTEIN 3 HOMOLOG-LIKE PROTEIN; 1.
DR PANTHER; PTHR14247:SF8; RAS-GEF DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF00617; RasGEF; 1.
DR Pfam; PF00017; SH2; 1.
DR PRINTS; PR00401; SH2DOMAIN.
DR SMART; SM00252; SH2; 1.
DR SUPFAM; SSF48366; Ras GEF; 1.
DR SUPFAM; SSF55550; SH2 domain; 1.
DR PROSITE; PS50001; SH2; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000054673};
KW SH2 domain {ECO:0000256|ARBA:ARBA00022999, ECO:0000256|PROSITE-
KW ProRule:PRU00191}.
FT DOMAIN 43..142
FT /note="SH2"
FT /evidence="ECO:0000259|PROSITE:PS50001"
FT REGION 705..748
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 705..745
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:KRX85110.1"
FT NON_TER 850
FT /evidence="ECO:0000313|EMBL:KRX85110.1"
SQ SEQUENCE 850 AA; 97286 MW; EF1F3A726B088B56 CRC64;
LLDLELKENS KMPSLIANEL CKWKLKLCVC CSVWKSRIDD HYWYHGSIDR SQAETLVLYP
GDFLVRDSLS REHDYVITCN WQGYPTHFAI SRTLQNQGTL YERAFFKIEE EQFDSIPALI
HFYVGNKQPL TRDSQCIISK PVNRDPASPP KPCVPFQVDN NRLGAVYQAV MQNGIDNIAI
PEVPDHIRNR PLPELPLIKE FQLQQQQQQQ RHYFKKSFKS SSEKKVSSVK QQQQQYLAEV
RNSSNTISFT NINSLEDGYI YTGNNFNGIV VDDSTKRADW LEEHEYCDID YEELLPIEKS
NSNAELLAAD VKIMNNNSNN NDNGVETNDE SETTTRAAAG SFLIYDAPSN GAPVDMNDIE
LQLTSRIHVQ SYTCEKFPVD LKPMDCRIWP EICKNLLQLD CAELCFCLNR EDVRFLSAHA
CSAHPLIPVD LSLLLLPQGD QFRKDIIERC TTLKYFIIMS ILNGDNFAQR VQLMVKWIEI
SEKMKNSFDN FFAFNSIIAA LSSSQITSIT SHWSNLRTNY TACAVTYESK LRRMYVEKLY
WNLNWVSNEM NFKGIPELET ICHLFQPINE KPNESFFDHL FRDDEHFGLE SIWQVLLEAR
KWKNVQLSSS GDQVQVEDPN SSSFANEMFQ TEFQIFTLWG IKGCLVCHAC KQASTTCTQP
SRAYPVFARQ ILLSIVITNA EIHPIKSAFS CGAFQMNQQR DFIEPTSPVS SSSTMGSSCV
KKTESIDNTE DTSGSGAYHG MNRSDNGQRC HQKFRSLRRL EPIRRESQHS GTFYYAIATL
ADATHDVGNI TQTLVHLQTP WSPYKDPLEV EALVRKAKAE MKTISVTNDC LFVDYRFVCH
LPPNAKIRAS
//
