ID A0A0V0XME5_TRIPS Unreviewed; 373 AA.
AC A0A0V0XME5;
DT 16-MAR-2016, integrated into UniProtKB/TrEMBL.
DT 16-MAR-2016, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE SubName: Full=Ras-related protein Rab-4B {ECO:0000313|EMBL:KRX89124.1};
GN Name=RAB4B {ECO:0000313|EMBL:KRX89124.1};
GN ORFNames=T4E_1013 {ECO:0000313|EMBL:KRX89124.1};
OS Trichinella pseudospiralis (Parasitic roundworm).
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Enoplea; Dorylaimia;
OC Trichinellida; Trichinellidae; Trichinella.
OX NCBI_TaxID=6337 {ECO:0000313|EMBL:KRX89124.1, ECO:0000313|Proteomes:UP000054815};
RN [1] {ECO:0000313|EMBL:KRX89124.1, ECO:0000313|Proteomes:UP000054815}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ISS141 {ECO:0000313|EMBL:KRX89124.1};
RA Korhonen P.K., Edoardo P., Giuseppe L.R., Gasser R.B.;
RT "Evolution of Trichinella species and genotypes.";
RL Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the small GTPase superfamily. Rab family.
CC {ECO:0000256|ARBA:ARBA00006270}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KRX89124.1}.
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DR EMBL; JYDU01000209; KRX89124.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0V0XME5; -.
DR STRING; 6337.A0A0V0XME5; -.
DR Proteomes; UP000054815; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0004869; F:cysteine-type endopeptidase inhibitor activity; IEA:InterPro.
DR GO; GO:0003925; F:G protein activity; IEA:UniProtKB-EC.
DR GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR GO; GO:0032482; P:Rab protein signal transduction; IEA:InterPro.
DR CDD; cd00042; CY; 1.
DR CDD; cd04113; Rab4; 1.
DR Gene3D; 3.10.450.10; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR000010; Cystatin_dom.
DR InterPro; IPR046350; Cystatin_sf.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR041819; Rab4.
DR InterPro; IPR005225; Small_GTP-bd_dom.
DR InterPro; IPR001806; Small_GTPase.
DR NCBIfam; TIGR00231; small_GTP; 1.
DR PANTHER; PTHR47979; DRAB11-RELATED; 1.
DR PANTHER; PTHR47979:SF24; SMALL MONOMERIC GTPASE; 1.
DR Pfam; PF00031; Cystatin; 1.
DR Pfam; PF00071; Ras; 1.
DR PRINTS; PR00449; RASTRNSFRMNG.
DR SMART; SM00043; CY; 1.
DR SMART; SM00175; RAB; 1.
DR SMART; SM00176; RAN; 1.
DR SMART; SM00173; RAS; 1.
DR SMART; SM00174; RHO; 1.
DR SUPFAM; SSF54403; Cystatin/monellin; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS51419; RAB; 1.
DR PROSITE; PS51421; RAS; 1.
DR PROSITE; PS51420; RHO; 1.
PE 3: Inferred from homology;
KW GTP-binding {ECO:0000256|ARBA:ARBA00023134};
KW Lipoprotein {ECO:0000256|ARBA:ARBA00023288};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00023134};
KW Reference proteome {ECO:0000313|Proteomes:UP000054815}.
FT DOMAIN 178..287
FT /note="Cystatin"
FT /evidence="ECO:0000259|SMART:SM00043"
SQ SEQUENCE 373 AA; 41433 MW; FC65B042DF1A3F5F CRC64;
MPGYLFKYLI IGNSGTGKSC VLHQFLENKF KQDTAHTIGI EFGSKVVKIQ DRSIKLQVWD
TAGQERFRSL TKNYYNGAAC ALLVYDITCR QSFNAIAQWL SDARSLASPQ IIVILIGNKK
DLEDRREVTF MEASQFAQEN GMLFLETSAL TGENIEETFL RCARSILTKI ESAVVGEPIV
GGLIPADDED PKVRQMIQYA VEQLNEKSKE PFLRKLITLK NAAVQVVQGA LYHLNILVAE
TDCKKGENVE NVQNCKTTPH GLSQECFVKI WEREWLNFIK VMKTKCKEAS LPDVNITDTT
KPTDNLQVGV IATPENYTIP IEEIATTVVV DQADEQQAST AVISSEAEIA ATLPVISTTD
ASLSNKTEQT ADM
//
