ID A0A0V0XUD8_TRIPS Unreviewed; 678 AA.
AC A0A0V0XUD8;
DT 16-MAR-2016, integrated into UniProtKB/TrEMBL.
DT 16-MAR-2016, sequence version 1.
DT 24-JAN-2024, entry version 19.
DE SubName: Full=Rap1 GTPase-activating protein 1 {ECO:0000313|EMBL:KRX91539.1};
GN Name=RAP1GAP {ECO:0000313|EMBL:KRX91539.1};
GN ORFNames=T4E_6693 {ECO:0000313|EMBL:KRX91539.1};
OS Trichinella pseudospiralis (Parasitic roundworm).
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Enoplea; Dorylaimia;
OC Trichinellida; Trichinellidae; Trichinella.
OX NCBI_TaxID=6337 {ECO:0000313|EMBL:KRX91539.1, ECO:0000313|Proteomes:UP000054815};
RN [1] {ECO:0000313|EMBL:KRX91539.1, ECO:0000313|Proteomes:UP000054815}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ISS141 {ECO:0000313|EMBL:KRX91539.1};
RA Korhonen P.K., Edoardo P., Giuseppe L.R., Gasser R.B.;
RT "Evolution of Trichinella species and genotypes.";
RL Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KRX91539.1}.
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DR EMBL; JYDU01000135; KRX91539.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0V0XUD8; -.
DR Proteomes; UP000054815; Unassembled WGS sequence.
DR GO; GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.
DR GO; GO:0051056; P:regulation of small GTPase mediated signal transduction; IEA:InterPro.
DR Gene3D; 3.40.50.11210; Rap/Ran-GAP; 1.
DR InterPro; IPR003109; GoLoco_motif.
DR InterPro; IPR035974; Rap/Ran-GAP_sf.
DR InterPro; IPR000331; Rap/Ran_GAP_dom.
DR PANTHER; PTHR15711:SF32; RAP GTPASE ACTIVATING PROTEIN 1, ISOFORM H; 1.
DR PANTHER; PTHR15711; RAP GTPASE-ACTIVATING PROTEIN; 1.
DR Pfam; PF02188; GoLoco; 1.
DR Pfam; PF21022; Rap-GAP_dimer; 1.
DR Pfam; PF02145; Rap_GAP; 1.
DR SMART; SM00390; GoLoco; 1.
DR SUPFAM; SSF111347; Rap/Ran-GAP; 1.
DR PROSITE; PS50877; GOLOCO; 1.
DR PROSITE; PS50085; RAPGAP; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW GTPase activation {ECO:0000256|ARBA:ARBA00022468};
KW Reference proteome {ECO:0000313|Proteomes:UP000054815}.
FT DOMAIN 279..495
FT /note="Rap-GAP"
FT /evidence="ECO:0000259|PROSITE:PS50085"
FT REGION 480..499
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 523..575
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 611..673
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 539..555
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 678 AA; 77026 MW; 2996082F22E1202D CRC64;
MFQHSINRSK TEIIYSILSH FYAIFGNYME WVWSWTDYAF ENICGCSSRN AYCVDNTGDA
VLQKHPSSGK IVCDVHQREV QSFSIPSQCH IQSNQTVELA LPLKHSVTES SDEKVQDFFA
LLERLQGNRL EDQRCSWPLP ICRPESLHQM IAHVLSRGGP FPTVVMPLHG GYWIDTASSE
EHLMESTCNS CQRLRLESDE TAKLYRRYFF GKDHFNFYAL DDRLGPIVLS VRVESTASQE
HLRIILRLKT GTIHEMVPAN RIGELLTAAR MAKFLCEDIS TECFTPVMFP KGTELIMTFD
EHTSEEELFG NAEHSDKMEE FLEFIGEKVQ LRNFKGFRGG LDTVHGQTGE ESFYTKFKDR
EIMFHVSTLL PYTVGDAQQL QRKRHIGNDI VAIIFQDDNT PFVPDMIASH FLHAYIVVTF
VDTGSSTTHY KVTVTARDDV PPFGPALPSP PIFIKGQELK TFLLTKLINA ENACYRARSK
HRHSAQLPEA ANVDRSDSAR KKDSFLSGDA LIKDNLHSGK STLTASKIDR RNVESGDHSN
ADVHSSSQID SESSSIDSAE LEHDSDTGME SMSSAETTNF KHLACMAWKD SPEKSCLTFI
NKDKCADFQK LQELLQEMSK LKNEKLDLLR QNVSCKSDIK KLKKRETQMS AELEAAYDEI
NKLQQLLKFS TSDRNQQM
//
