ID A0A0V0XVN0_TRIPS Unreviewed; 1590 AA.
AC A0A0V0XVN0;
DT 16-MAR-2016, integrated into UniProtKB/TrEMBL.
DT 16-MAR-2016, sequence version 1.
DT 27-MAR-2024, entry version 29.
DE SubName: Full=Protein NDNF {ECO:0000313|EMBL:KRX92164.1};
GN Name=NDNF {ECO:0000313|EMBL:KRX92164.1};
GN ORFNames=T4E_9518 {ECO:0000313|EMBL:KRX92164.1};
OS Trichinella pseudospiralis (Parasitic roundworm).
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Enoplea; Dorylaimia;
OC Trichinellida; Trichinellidae; Trichinella.
OX NCBI_TaxID=6337 {ECO:0000313|EMBL:KRX92164.1, ECO:0000313|Proteomes:UP000054815};
RN [1] {ECO:0000313|EMBL:KRX92164.1, ECO:0000313|Proteomes:UP000054815}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ISS141 {ECO:0000313|EMBL:KRX92164.1};
RA Korhonen P.K., Edoardo P., Giuseppe L.R., Gasser R.B.;
RT "Evolution of Trichinella species and genotypes.";
RL Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000256|ARBA:ARBA00004613}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KRX92164.1}.
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DR EMBL; JYDU01000118; KRX92164.1; -; Genomic_DNA.
DR Proteomes; UP000054815; Unassembled WGS sequence.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR GO; GO:0030414; F:peptidase inhibitor activity; IEA:InterPro.
DR GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR CDD; cd00159; RhoGAP; 1.
DR CDD; cd19941; TIL; 1.
DR CDD; cd00199; WAP; 1.
DR Gene3D; 4.10.75.10; Elafin-like; 2.
DR Gene3D; 2.10.25.10; Laminin; 1.
DR Gene3D; 1.10.555.10; Rho GTPase activation protein; 1.
DR InterPro; IPR036645; Elafin-like_sf.
DR InterPro; IPR019326; NDNF.
DR InterPro; IPR045805; NDNF_C.
DR InterPro; IPR008936; Rho_GTPase_activation_prot.
DR InterPro; IPR000198; RhoGAP_dom.
DR InterPro; IPR002919; TIL_dom.
DR InterPro; IPR008197; WAP_dom.
DR PANTHER; PTHR14619:SF3; FI20196P1; 1.
DR PANTHER; PTHR14619; NEURON-DERIVED NEUROTROPHIC FACTOR; 1.
DR Pfam; PF10179; NDNF; 1.
DR Pfam; PF19433; NDNF_C; 1.
DR Pfam; PF00620; RhoGAP; 1.
DR Pfam; PF01826; TIL; 1.
DR Pfam; PF00095; WAP; 3.
DR SMART; SM00324; RhoGAP; 1.
DR SMART; SM00217; WAP; 2.
DR SUPFAM; SSF57256; Elafin-like; 3.
DR SUPFAM; SSF48350; GTPase activation domain, GAP; 1.
DR PROSITE; PS50238; RHOGAP; 1.
DR PROSITE; PS51390; WAP; 2.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000054815};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Secreted {ECO:0000256|ARBA:ARBA00022525}.
FT DOMAIN 111..160
FT /note="WAP"
FT /evidence="ECO:0000259|PROSITE:PS51390"
FT DOMAIN 232..282
FT /note="WAP"
FT /evidence="ECO:0000259|PROSITE:PS51390"
FT DOMAIN 884..1092
FT /note="Rho-GAP"
FT /evidence="ECO:0000259|PROSITE:PS50238"
FT REGION 1140..1161
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1389..1418
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1537..1578
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1544..1578
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1590 AA; 179465 MW; B696EB5D434D7EED CRC64;
MNDTYALALD MLDNMLVWDD NCHKQGGHFD IVSRWPLEDV LNCVGAADPD EADAEAVAVL
ATDAGSVAQF RLPRYTAKLI YCTLIVFHML YTRLLFSLCV VTCLTSVSHL QRVKVGRCPE
LPARYLTNQL QHDRCRDDYD CDSTMKCCES IIGKVCMMPK DYDQKEVCKQ PYTKWDSCGG
GCMTTCYNIG WQQPCRQSCQ PGCTCISGFV RLYLHPYAPC VPQIHCPNQR TTRKKFGVCP
TLPQGAEIDY HRRRDRCGTD FDCSGYMKCC ESIIGKACML PLCTCPDGQK TSIFCDERDS
CPWGYTCRSG LCCPNAPWQS PTATWPGQVT TAAGNCPHYA YIGTWAQLAP SCFTNSNCAY
NQLCCYTYYG NRCIQVSQSA LSFYIGKQNY MTNRLYDNVF KEPHYPDSWH EDEETLYKNA
GEKQMNYVSK TASMLHVRLY LTGLRRICKV EIRFGTTPVE KHLFFQLFHL TQPKIDNIQS
KSVTLSWKPS MSALLYTGGR LVYVIALSTV RPFATLCDLE TDLKLDRVNL LEHRRQEHVA
HRLIPQHHSG AVRSLTVLDA TGPAKLQLIS LQQNTNYYAN VFALDLNTGE NIAYNTVSFT
TTSENQISQH RLVSSLTEAQ LQTGYLGPSR VAFKVYQFSA PVAISELYIL IQPCTGPLQA
AIYQDGQKTL HYSIEELQAI NLTGVNVGIV QIQIANDDNQ AKIFNIWASN NYSAYPYPKL
PYDTSITVTE RKCDSVQLSW LASTDAHVYC LYKRVQRFDY FKQLTLEDWN LCQQPDENLQ
PLFCNQFRGN QYRNEILIQE IAALKPATTY RFDLFVSKHN QPSLAYRTVW SRSFSVVLNE
DLVADGADRL NSDFLRTISL WVNKYLRRSR TQEMDSPPNP LVLSGLRSLL YTFPDGVTFT
VPIFLHKAFS VLEAHYLTTE GIFRKPGIAS KLRVLKNCFN ASSALELNFK IEEVSPFDLC
DLIKLFLREI DEPILTWGLQ PQFLQFADLN TPRDVRTKCL LQLCHALPPR HKETLAFIMR
FLKMISNSSA YNKMDVKNLA TVFVPCIFRE SAKARPVKHG QALLDELAAS KSDIALKVDV
LEMLIQNADS IGVLSEQERA ILAAESSDKL NDDLNILKRS AKKAASKVLV RSRNSLSGNR
NSQIYRRSVQ PKLKSAESIE RHERIKGSRI TEPYKRRSVC SLEKSQGLSD KGENAIIRQN
RCLQEKHVKP MRSSMFETIY SSAFTEGIST SSVIEEQCTT SPILRTSSLP DRKVISTENR
ECLKVNKAEG ELVRAEPVQT VLRGTTVQFM SSDNELQDAY SKQSCLYEEL SSALDNFAKT
INVGLKSPVE RMEVCCTEVE LLHAEEEEDK TKKNDAKGKE ARLPRCISAP VESVPQAGGT
FAKKRNTSLG ASKLRRGMPN SLKSGLREPK TPFSSPLKNQ QQANIKASSN NMDKNNSVVV
AVEQPERNLE IESKENIIQT TKVSSTNMDI VEDDEFKDSD MKKQIILQQI NPDDDDNHPA
SEVGFCIRPS VNFIREHRKG HVRSKIQEFT DRESRLEFVG EETDSSSVIG QSPAEISKRT
TTSKPTATRK PSSSSGNKGC SLNIKFSACF
//
