ID A0A0V0Y0J4_TRIPS Unreviewed; 473 AA.
AC A0A0V0Y0J4;
DT 16-MAR-2016, integrated into UniProtKB/TrEMBL.
DT 16-MAR-2016, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE SubName: Full=Cysteine-rich with EGF-like domain protein 2 {ECO:0000313|EMBL:KRX93586.1};
GN Name=Creld1 {ECO:0000313|EMBL:KRX93586.1};
GN ORFNames=T4E_270 {ECO:0000313|EMBL:KRX93586.1};
OS Trichinella pseudospiralis (Parasitic roundworm).
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Enoplea; Dorylaimia;
OC Trichinellida; Trichinellidae; Trichinella.
OX NCBI_TaxID=6337 {ECO:0000313|EMBL:KRX93586.1, ECO:0000313|Proteomes:UP000054815};
RN [1] {ECO:0000313|EMBL:KRX93586.1, ECO:0000313|Proteomes:UP000054815}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ISS141 {ECO:0000313|EMBL:KRX93586.1};
RA Korhonen P.K., Edoardo P., Giuseppe L.R., Gasser R.B.;
RT "Evolution of Trichinella species and genotypes.";
RL Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the CRELD family.
CC {ECO:0000256|ARBA:ARBA00005897}.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00076}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KRX93586.1}.
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DR EMBL; JYDU01000086; KRX93586.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0V0Y0J4; -.
DR Proteomes; UP000054815; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR CDD; cd00054; EGF_CA; 1.
DR CDD; cd00064; FU; 1.
DR Gene3D; 1.10.1740.140; -; 1.
DR Gene3D; 2.10.25.10; Laminin; 1.
DR InterPro; IPR021852; DUF3456.
DR InterPro; IPR001881; EGF-like_Ca-bd_dom.
DR InterPro; IPR000742; EGF-like_dom.
DR InterPro; IPR000152; EGF-type_Asp/Asn_hydroxyl_site.
DR InterPro; IPR018097; EGF_Ca-bd_CS.
DR InterPro; IPR006212; Furin_repeat.
DR InterPro; IPR009030; Growth_fac_rcpt_cys_sf.
DR InterPro; IPR002049; LE_dom.
DR PANTHER; PTHR24038:SF13; PROTEIN DISULFIDE-ISOMERASE; 1.
DR PANTHER; PTHR24038; STABILIN; 1.
DR Pfam; PF11938; DUF3456; 2.
DR Pfam; PF07645; EGF_CA; 1.
DR SMART; SM00181; EGF; 3.
DR SMART; SM00179; EGF_CA; 1.
DR SMART; SM00261; FU; 1.
DR SUPFAM; SSF57184; Growth factor receptor domain; 1.
DR PROSITE; PS00010; ASX_HYDROXYL; 1.
DR PROSITE; PS00022; EGF_1; 1.
DR PROSITE; PS50026; EGF_3; 2.
DR PROSITE; PS01187; EGF_CA; 1.
DR PROSITE; PS01248; EGF_LAM_1; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157, ECO:0000256|PROSITE-
KW ProRule:PRU00076};
KW EGF-like domain {ECO:0000256|ARBA:ARBA00022536, ECO:0000256|PROSITE-
KW ProRule:PRU00076}; Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000054815};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Signal {ECO:0000256|ARBA:ARBA00022729};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 416..434
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 441..460
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 263..303
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 357..396
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT COILED 201..228
FT /evidence="ECO:0000256|SAM:Coils"
FT DISULFID 293..302
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
SQ SEQUENCE 473 AA; 52781 MW; 5DA0ECCC7EC15777 CRC64;
MASVKAVVTA LRNIGRLPQL RHLSGSKKSF EDLVVPLTVK SASTINDVNV GVEFGGILAK
DALASVLSQF ARRPALGFIL QTRSQRISFC NVSFSWRRIR PNKTILTTNR HQQNRLACCC
AINVLLVVDL ASRATDVPPG DRCDTCRFLA RSFEKGFNDT NKSHFEGGNT AWENENLGKY
STSETRFIEI MELICSKKSK HVKEESKIKN LESKCHAMAE EYEETLETWY YHNRKEYPDL
FDWFCIKTVK VCCPDNTFGA SCAPCPGDPK RPCFGNGICE GSGSRFGSGK CKCHRGYQGK
LCRHCDSNFF KVHSNETYIL CQPCHESCKG GCNGEGPKEC HSCRAGWIMD EDTGCKDIDE
CESSPCTDQF EKCENTPGSY KCVCAEAFRR EDGVCIPDPD VPRPKPVFFG LLAQQVLRYA
SYFGLLLSFL LILLRPKTPL IVLFTCSLVI IALIEAGHAV RMLNAIFLGD QAL
//
