ID A0A0V0Y0R6_TRIPS Unreviewed; 232 AA.
AC A0A0V0Y0R6;
DT 16-MAR-2016, integrated into UniProtKB/TrEMBL.
DT 16-MAR-2016, sequence version 1.
DT 13-SEP-2023, entry version 17.
DE RecName: Full=isopentenyl-diphosphate Delta-isomerase {ECO:0000256|ARBA:ARBA00012057};
DE EC=5.3.3.2 {ECO:0000256|ARBA:ARBA00012057};
GN Name=IPI2 {ECO:0000313|EMBL:KRX93880.1};
GN ORFNames=T4E_7668 {ECO:0000313|EMBL:KRX93880.1};
OS Trichinella pseudospiralis (Parasitic roundworm).
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Enoplea; Dorylaimia;
OC Trichinellida; Trichinellidae; Trichinella.
OX NCBI_TaxID=6337 {ECO:0000313|EMBL:KRX93880.1, ECO:0000313|Proteomes:UP000054815};
RN [1] {ECO:0000313|EMBL:KRX93880.1, ECO:0000313|Proteomes:UP000054815}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ISS141 {ECO:0000313|EMBL:KRX93880.1};
RA Korhonen P.K., Edoardo P., Giuseppe L.R., Gasser R.B.;
RT "Evolution of Trichinella species and genotypes.";
RL Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Catalyzes the 1,3-allylic rearrangement of the homoallylic
CC substrate isopentenyl (IPP) to its highly electrophilic allylic isomer,
CC dimethylallyl diphosphate (DMAPP). {ECO:0000256|ARBA:ARBA00003951}.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=isopentenyl diphosphate = dimethylallyl diphosphate;
CC Xref=Rhea:RHEA:23284, ChEBI:CHEBI:57623, ChEBI:CHEBI:128769;
CC EC=5.3.3.2; Evidence={ECO:0000256|ARBA:ARBA00000374};
CC -!- PATHWAY: Isoprenoid biosynthesis; dimethylallyl diphosphate
CC biosynthesis; dimethylallyl diphosphate from isopentenyl diphosphate:
CC step 1/1. {ECO:0000256|ARBA:ARBA00004826}.
CC -!- SIMILARITY: Belongs to the IPP isomerase type 1 family.
CC {ECO:0000256|ARBA:ARBA00007579}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KRX93880.1}.
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DR EMBL; JYDU01000081; KRX93880.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0V0Y0R6; -.
DR STRING; 6337.A0A0V0Y0R6; -.
DR UniPathway; UPA00059; UER00104.
DR Proteomes; UP000054815; Unassembled WGS sequence.
DR GO; GO:0004452; F:isopentenyl-diphosphate delta-isomerase activity; IEA:UniProtKB-EC.
DR GO; GO:0050992; P:dimethylallyl diphosphate biosynthetic process; IEA:UniProtKB-UniPathway.
DR GO; GO:0008299; P:isoprenoid biosynthetic process; IEA:UniProtKB-KW.
DR Gene3D; 3.90.79.10; Nucleoside Triphosphate Pyrophosphohydrolase; 1.
DR InterPro; IPR011876; IsopentenylPP_isomerase_typ1.
DR InterPro; IPR015797; NUDIX_hydrolase-like_dom_sf.
DR InterPro; IPR000086; NUDIX_hydrolase_dom.
DR NCBIfam; TIGR02150; IPP_isom_1; 1.
DR PANTHER; PTHR10885; ISOPENTENYL-DIPHOSPHATE DELTA-ISOMERASE; 1.
DR PANTHER; PTHR10885:SF0; ISOPENTENYL-DIPHOSPHATE DELTA-ISOMERASE; 1.
DR Pfam; PF00293; NUDIX; 1.
DR PIRSF; PIRSF018427; Isopntndiph_ism; 1.
DR SUPFAM; SSF55811; Nudix; 1.
DR PROSITE; PS51462; NUDIX; 1.
PE 3: Inferred from homology;
KW Isomerase {ECO:0000256|ARBA:ARBA00023235, ECO:0000313|EMBL:KRX93880.1};
KW Isoprene biosynthesis {ECO:0000256|ARBA:ARBA00023229};
KW Reference proteome {ECO:0000313|Proteomes:UP000054815}.
FT DOMAIN 52..203
FT /note="Nudix hydrolase"
FT /evidence="ECO:0000259|PROSITE:PS51462"
SQ SEQUENCE 232 AA; 27490 MW; 036405683D244F18 CRC64;
MLRLVKRFPW SVKPLFLHSS VNCVAVDRYD HCLGSISIED AHNWKLIQDD VALHRAFSVF
LFRSDGRMLI QKRASSKTTF PGYWSNACCS HPRFMPDETN SDPPFSGIKC AAQRRMSEEF
KIPLIPLESF QFIDRFIYKA QFNESLGEHE LDYVFFVRSD LLIEPNFNEV ELIQYVKEDQ
LKELLELSDR KPEIMQFAPW FRLIAKNFLF FWWKHLGDLQ SIQNFETIHI LD
//
