ID A0A0V0YC01_TRIPS Unreviewed; 710 AA.
AC A0A0V0YC01;
DT 16-MAR-2016, integrated into UniProtKB/TrEMBL.
DT 16-MAR-2016, sequence version 1.
DT 27-MAR-2024, entry version 28.
DE SubName: Full=Double C2-like domain-containing protein beta {ECO:0000313|EMBL:KRX97273.1};
DE Flags: Fragment;
GN Name=Doc2b {ECO:0000313|EMBL:KRX97273.1};
GN ORFNames=T4E_3145 {ECO:0000313|EMBL:KRX97273.1};
OS Trichinella pseudospiralis (Parasitic roundworm).
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Enoplea; Dorylaimia;
OC Trichinellida; Trichinellidae; Trichinella.
OX NCBI_TaxID=6337 {ECO:0000313|EMBL:KRX97273.1, ECO:0000313|Proteomes:UP000054815};
RN [1] {ECO:0000313|EMBL:KRX97273.1, ECO:0000313|Proteomes:UP000054815}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ISS141 {ECO:0000313|EMBL:KRX97273.1};
RA Korhonen P.K., Edoardo P., Giuseppe L.R., Gasser R.B.;
RT "Evolution of Trichinella species and genotypes.";
RL Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KRX97273.1}.
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DR EMBL; JYDU01000033; KRX97273.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0V0YC01; -.
DR Proteomes; UP000054815; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:InterPro.
DR GO; GO:0008021; C:synaptic vesicle; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0031267; F:small GTPase binding; IEA:InterPro.
DR GO; GO:0006887; P:exocytosis; IEA:InterPro.
DR GO; GO:0006886; P:intracellular protein transport; IEA:InterPro.
DR CDD; cd04035; C2A_Rabphilin_Doc2; 1.
DR CDD; cd15746; FYVE_RP3A_like; 1.
DR Gene3D; 2.60.40.150; C2 domain; 2.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR000008; C2_dom.
DR InterPro; IPR035892; C2_domain_sf.
DR InterPro; IPR041282; FYVE_2.
DR InterPro; IPR030541; FYVE_RBF-1.
DR InterPro; IPR010911; Rab_BD.
DR InterPro; IPR043566; Rabphilin/DOC2/Noc2.
DR InterPro; IPR047022; Rabphilin_Doc2_C2A.
DR InterPro; IPR001565; Synaptotagmin.
DR InterPro; IPR017455; Znf_FYVE-rel.
DR InterPro; IPR011011; Znf_FYVE_PHD.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR PANTHER; PTHR45729:SF4; RAB EFFECTOR NOC2; 1.
DR PANTHER; PTHR45729; RABPHILIN, ISOFORM A; 1.
DR Pfam; PF00168; C2; 2.
DR Pfam; PF02318; FYVE_2; 1.
DR PRINTS; PR00360; C2DOMAIN.
DR PRINTS; PR00399; SYNAPTOTAGMN.
DR SMART; SM00239; C2; 2.
DR SUPFAM; SSF49562; C2 domain (Calcium/lipid-binding domain, CaLB); 2.
DR SUPFAM; SSF57903; FYVE/PHD zinc finger; 1.
DR PROSITE; PS50004; C2; 2.
DR PROSITE; PS50916; RABBD; 1.
DR PROSITE; PS50178; ZF_FYVE; 1.
PE 4: Predicted;
KW Exocytosis {ECO:0000256|ARBA:ARBA00022483};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000054815};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Synapse {ECO:0000256|ARBA:ARBA00023018};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00091}.
FT DOMAIN 43..163
FT /note="RabBD"
FT /evidence="ECO:0000259|PROSITE:PS50916"
FT DOMAIN 91..151
FT /note="FYVE-type"
FT /evidence="ECO:0000259|PROSITE:PS50178"
FT DOMAIN 437..559
FT /note="C2"
FT /evidence="ECO:0000259|PROSITE:PS50004"
FT DOMAIN 575..704
FT /note="C2"
FT /evidence="ECO:0000259|PROSITE:PS50004"
FT REGION 203..234
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 249..362
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 254..274
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 275..289
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 290..308
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 309..341
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 342..362
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:KRX97273.1"
SQ SEQUENCE 710 AA; 80830 MW; CF9598D74A95DF02 CRC64;
LKYIRKSTKM PGKQNSWICP SDRFLILRSQ LSAGWSVWSD TQRADKSTIS DNEMQQIKDV
LARAEHIEEN EQRRIGKLVE RLDRMKKMAA GNGINQCMLC GAKFGMIGTR SFASFCHDCN
KYVCQKNCGL ETLDSNGQTI YLCKLCSETR EMWKKSGAWF YRGIPNFIKD TGLRSKSNDV
SLSNTDDRGG FDTVSLTSMD SRCSKESLPS WSGKAKHAKR LLPTPPSESH IRPSQPRWAI
ISQSIQSFDK CVDSSSEEEE EDSKDGQETE EDIEQNNENL NRRLFLDDSD TPYSRQSSCL
SELDNSKPLS ELESPELKRL SEEEKRTARD VKEEETEIYD SKSSTSEVAV HSDSPVQSCT
NSSSRYTMEI AEDSDASMAL STSVHDQATS EVNRITDQLA ECSMSKPYAT KNLQHSDSAK
SFDSSLYDSS PDNDITNFGS LEYSLLYDET EEMLIVTIFQ ASNLPAMDSN GFSDPYVKLH
LLPLANKSTK LRTSTKWKTL NPRWNERLIY YGMSKDDLRK KTLRLMVLDQ DRIGSDFLGE
TRAPLKRLQS GKEKYFNVYL EKQMPVEKCD EFTEERGKIL LALCYDLQNK LLAVEVVRCV
ELVGMDSTGY SDPTLKPGTL KSYHVKTEVK KKTLNPEYNR VFQFPVSYDE LAKKSLDVEV
WDKDVGKLDD FIGSVTLSAN AKSDRLKHWI ECIQNPNKRI KKWHKLTGKV
//
