ID A0A0V0YD32_TRIPS Unreviewed; 1025 AA.
AC A0A0V0YD32;
DT 16-MAR-2016, integrated into UniProtKB/TrEMBL.
DT 16-MAR-2016, sequence version 1.
DT 27-MAR-2024, entry version 30.
DE SubName: Full=Putative pre-mRNA-splicing factor ATP-dependent RNA helicase mog-5 {ECO:0000313|EMBL:KRX98310.1};
GN Name=mog-5 {ECO:0000313|EMBL:KRX98310.1};
GN ORFNames=T4E_10348 {ECO:0000313|EMBL:KRX98310.1};
OS Trichinella pseudospiralis (Parasitic roundworm).
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Enoplea; Dorylaimia;
OC Trichinellida; Trichinellidae; Trichinella.
OX NCBI_TaxID=6337 {ECO:0000313|EMBL:KRX98310.1, ECO:0000313|Proteomes:UP000054815};
RN [1] {ECO:0000313|EMBL:KRX98310.1, ECO:0000313|Proteomes:UP000054815}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ISS141 {ECO:0000313|EMBL:KRX98310.1};
RA Korhonen P.K., Edoardo P., Giuseppe L.R., Gasser R.B.;
RT "Evolution of Trichinella species and genotypes.";
RL Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + H2O = ADP + H(+) + phosphate; Xref=Rhea:RHEA:13065,
CC ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=3.6.4.13;
CC Evidence={ECO:0000256|ARBA:ARBA00001556};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KRX98310.1}.
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DR EMBL; JYDU01000022; KRX98310.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0V0YD32; -.
DR STRING; 6337.A0A0V0YD32; -.
DR Proteomes; UP000054815; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-KW.
DR GO; GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR CDD; cd21691; GH2-like_DHX8; 1.
DR CDD; cd05684; S1_DHX8_helicase; 1.
DR CDD; cd18791; SF2_C_RHA; 1.
DR Gene3D; 1.20.120.1080; -; 1.
DR Gene3D; 2.40.50.140; Nucleic acid-binding proteins; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR011709; DEAD-box_helicase_OB_fold.
DR InterPro; IPR049588; DHX8_GH2-like.
DR InterPro; IPR048333; HA2_WH.
DR InterPro; IPR007502; Helicase-assoc_dom.
DR InterPro; IPR001650; Helicase_C.
DR InterPro; IPR012340; NA-bd_OB-fold.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR049621; S1_DHX8_helicase.
DR InterPro; IPR003029; S1_domain.
DR PANTHER; PTHR18934; ATP-DEPENDENT RNA HELICASE; 1.
DR PANTHER; PTHR18934:SF85; ATP-DEPENDENT RNA HELICASE DHX8; 1.
DR Pfam; PF21010; HA2_C; 1.
DR Pfam; PF04408; HA2_N; 1.
DR Pfam; PF00271; Helicase_C; 1.
DR Pfam; PF07717; OB_NTP_bind; 1.
DR Pfam; PF00575; S1; 1.
DR SMART; SM00847; HA2; 1.
DR SMART; SM00490; HELICc; 1.
DR SMART; SM00316; S1; 1.
DR SUPFAM; SSF50249; Nucleic acid-binding proteins; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR PROSITE; PS51194; HELICASE_CTER; 1.
DR PROSITE; PS50126; S1; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000313|EMBL:KRX98310.1};
KW Helicase {ECO:0000313|EMBL:KRX98310.1};
KW Hydrolase {ECO:0000313|EMBL:KRX98310.1};
KW mRNA processing {ECO:0000256|ARBA:ARBA00022664};
KW mRNA splicing {ECO:0000256|ARBA:ARBA00023187};
KW Nucleotide-binding {ECO:0000313|EMBL:KRX98310.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000054815}.
FT DOMAIN 237..307
FT /note="S1 motif"
FT /evidence="ECO:0000259|PROSITE:PS50126"
FT DOMAIN 547..736
FT /note="Helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51194"
FT REGION 129..221
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 307..329
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 458..489
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 129..174
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 193..221
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 315..329
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 459..473
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1025 AA; 117034 MW; C2415E20040ABCA2 CRC64;
MEEMERLQYI SLVSKICTEL ENHLGLSDKD LAEFIIHLGQ KNPTFESFKS ALESNGAEFD
NSLISNLLRR IQLMSKPTGK SENADENASH MLSMSSKSDR EVMKQCLPAL AMPNKPVSET
LSELENLIPQ WRRENETEQK ENAGDGSRDE RKKRERRRSR DRSRSCDSSE RRTERHRARR
RRSSSFSGES SRKHASRRRR SRSGSELRTK LKSRRRSRSG ERISRIRIKL DDTPIVGKIY
DGRVNSIRDF GCFVELFGLR RHVEGLVHIS QIKNERVNAV TDVVTRGQKV KVKVLACSGN
RTSLSMREVD QETGEDLNPT EDVDQEEQPF DETLQLRNPD LPSAAQQKLM QLQAEEFKAS
TSKRIKRLSS PERWELKQMM AASCISTADL PDFDEETGVL LQEDMLDDHE EDVEVELVEE
EPQFLQGYGR VRQDLEPIKV VKNPDGSLAQ AAMMQGALAK ERREQKIQQQ RERGNEQLGR
GSGAASKSFL DPLADADNKY SKVLQNVERK HMDLPEWKRH IAAGKSFGKP QGSMTILEQR
QSLPIYKLRG ELVKAVSENQ ILIVIGETGS GKTTQITQYL AEEGFTFSGK IACTQPRRSL
GPDVPELIIL PVYSALPSEM QTRIFESAPP GSRKVVIATN IAETSLTIDG IYYVVDPGFV
KQKIYNPKTG MDSLVVTPIS QAQAKQRSGR AGRTGPGKCY RLYTERAYRD EMLPTPVPEI
QRTNLASTLL QLKAMGINNL IDFDFMDPPP VEAMVMALEQ LHSLSALDDE GLLTRVGRRM
AEFPLEPSLS KLLIMSVHLG CSEEVLTIVS MISVQNVFYR PKDKQDVADQ KKSKFHQPEG
DHLTLLAVYN SWKNHRYSHS WCYENFVQIR TLKRAQDIRK QLLGIMDRHR LDMISCGKNM
QKVQKAICSG FFRNAAKKDP QEGYRTLVDS QTVYIHPSSS LFHNQPEWVV YHELVMTTKE
YMREVCAIEP KWLVEFAPAF FRFGDPTKLS KFKKGQKIEP LFNKYEDVNA WRISKVKKKI
YNPNR
//
