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Database: UniProt
Entry: A0A0V0YEW6_TRIPS
LinkDB: A0A0V0YEW6_TRIPS
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ID   A0A0V0YEW6_TRIPS        Unreviewed;      4254 AA.
AC   A0A0V0YEW6;
DT   16-MAR-2016, integrated into UniProtKB/TrEMBL.
DT   16-MAR-2016, sequence version 1.
DT   28-FEB-2018, entry version 14.
DE   SubName: Full=Ryanodine receptor 44F {ECO:0000313|EMBL:KRX98604.1};
GN   Name=Rya-r44F {ECO:0000313|EMBL:KRX98604.1};
GN   ORFNames=T4E_7573 {ECO:0000313|EMBL:KRX98604.1};
OS   Trichinella pseudospiralis (Parasitic roundworm).
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Enoplea; Dorylaimia;
OC   Trichinellida; Trichinellidae; Trichinella.
OX   NCBI_TaxID=6337 {ECO:0000313|EMBL:KRX98604.1, ECO:0000313|Proteomes:UP000054815};
RN   [1] {ECO:0000313|EMBL:KRX98604.1, ECO:0000313|Proteomes:UP000054815}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ISS141 {ECO:0000313|EMBL:KRX98604.1};
RA   Korhonen P.K., Edoardo P., Giuseppe L.R., Gasser R.B.;
RT   "Evolution of Trichinella species and genotypes.";
RL   Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an
CC       EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is
CC       preliminary data. {ECO:0000313|EMBL:KRX98604.1}.
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DR   EMBL; JYDU01000020; KRX98604.1; -; Genomic_DNA.
DR   Proteomes; UP000054815; Unassembled WGS sequence.
DR   GO; GO:0005623; C:cell; IEA:GOC.
DR   GO; GO:0016020; C:membrane; IEA:InterPro.
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0005219; F:ryanodine-sensitive calcium-release channel activity; IEA:InterPro.
DR   CDD; cd00051; EFh; 1.
DR   CDD; cd12878; SPRY2_RyR; 1.
DR   CDD; cd12879; SPRY3_RyR; 1.
DR   InterPro; IPR001870; B30.2/SPRY.
DR   InterPro; IPR013320; ConA-like_dom_sf.
DR   InterPro; IPR011992; EF-hand-dom_pair.
DR   InterPro; IPR018247; EF_Hand_1_Ca_BS.
DR   InterPro; IPR002048; EF_hand_dom.
DR   InterPro; IPR014821; Ins145_P3_rcpt.
DR   InterPro; IPR036300; MIR_dom_sf.
DR   InterPro; IPR016093; MIR_motif.
DR   InterPro; IPR013662; RIH_assoc-dom.
DR   InterPro; IPR000699; RIH_dom.
DR   InterPro; IPR013333; Ryan_recept.
DR   InterPro; IPR003032; Ryanodine_rcpt.
DR   InterPro; IPR015925; Ryanodine_recept-rel.
DR   InterPro; IPR035910; RyR/IP3R_RIH_dom_sf.
DR   InterPro; IPR035764; SPRY2_RyR.
DR   InterPro; IPR035762; SPRY3_RyR.
DR   InterPro; IPR003877; SPRY_dom.
DR   PANTHER; PTHR13715; PTHR13715; 2.
DR   Pfam; PF13499; EF-hand_7; 1.
DR   Pfam; PF08709; Ins145_P3_rec; 1.
DR   Pfam; PF02815; MIR; 1.
DR   Pfam; PF08454; RIH_assoc; 1.
DR   Pfam; PF01365; RYDR_ITPR; 2.
DR   Pfam; PF02026; RyR; 4.
DR   Pfam; PF00622; SPRY; 3.
DR   PRINTS; PR00795; RYANODINER.
DR   SMART; SM00054; EFh; 2.
DR   SMART; SM00472; MIR; 4.
DR   SMART; SM00449; SPRY; 3.
DR   SUPFAM; SSF100909; SSF100909; 1.
DR   SUPFAM; SSF47473; SSF47473; 1.
DR   SUPFAM; SSF49899; SSF49899; 2.
DR   SUPFAM; SSF82109; SSF82109; 2.
DR   PROSITE; PS50188; B302_SPRY; 2.
DR   PROSITE; PS00018; EF_HAND_1; 2.
DR   PROSITE; PS50222; EF_HAND_2; 2.
DR   PROSITE; PS50919; MIR; 5.
PE   4: Predicted;
KW   Calcium {ECO:0000256|PROSITE-ProRule:PRU00448};
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Complete proteome {ECO:0000313|Proteomes:UP000054815};
KW   Receptor {ECO:0000313|EMBL:KRX98604.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000054815};
KW   Repeat {ECO:0000256|SAAS:SAAS00903904}.
FT   DOMAIN      109    163       MIR. {ECO:0000259|PROSITE:PS50919}.
FT   DOMAIN      170    214       MIR. {ECO:0000259|PROSITE:PS50919}.
FT   DOMAIN      224    278       MIR. {ECO:0000259|PROSITE:PS50919}.
FT   DOMAIN      284    331       MIR. {ECO:0000259|PROSITE:PS50919}.
FT   DOMAIN      328    386       MIR. {ECO:0000259|PROSITE:PS50919}.
FT   DOMAIN      566    801       B30.2/SPRY. {ECO:0000259|PROSITE:
FT                                PS50188}.
FT   DOMAIN     1048   1229       B30.2/SPRY. {ECO:0000259|PROSITE:
FT                                PS50188}.
FT   DOMAIN     4182   4217       EF-hand. {ECO:0000259|PROSITE:PS50222}.
FT   DOMAIN     4220   4252       EF-hand. {ECO:0000259|PROSITE:PS50222}.
FT   CA_BIND    4195   4206       {ECO:0000256|PROSITE-ProRule:PRU00448}.
FT   CA_BIND    4230   4241       {ECO:0000256|PROSITE-ProRule:PRU00448}.
FT   COILED     3872   3892       {ECO:0000256|SAM:Coils}.
SQ   SEQUENCE   4254 AA;  483552 MW;  8ACD918B610315DD CRC64;
     MTDFQENSTG EQDDISFLRT VLKKGDVVCL TCLAPCKESG TGSAERVSLA AEGFGNRICY
     LENVSDKNKP PDNATSMFYI DQALSVRALQ EMMSSELPNI SVRGSSSTHR TLLYGHAVQL
     KHTLSGMYLT CLSTSSASDK LAFDVGLCET NVGESCWWTI HPASKQRSEG EKVRFGDDVI
     LVSVATERYL HMSSTNGNTV LAAFHQTLWS ITPNSAGGVR ARHMGYVCGN DVLRLNHGND
     ECLTIPENWS DSSQNNIVIY ENGKSCNQAR SLWRPELIHG KWQSSLLGWE QAFRIRHITS
     GRFLALNEDN QDVKRSTFEE KEEEGMGVAT VKYGETVIFL QHLQSNLWLS CQTTAVTKKN
     MGKVEEKKAI AVEEARMDDC FILFKAQEEE SQSARVIRKC SQILNRFLRG LEGLQMEGKD
     SLAWNRADLS ETVKLMEDLI QYFAQPEETV DFESMQNGLR ALRNRQDLFQ EEGLLNMIID
     TIDQFSVVES MTELLDVTKE DKCKDWQDIS TYLYLLVAAM IKGNHSNCTQ FASAQRLNWL
     FSRLSNPQSA EGILDVLYCI LTESPEALNM INEDHVKAVI SLLEKVGHDP KVLNVLSALC
     EGNGVAVRNS QNVICSELLC NKKFLLQTKM IDQVSSVMAN IFVGSYENSA MYPRWYFEAE
     LEYMESMHTS GQKPHLRIGW ASSAGYRAYP GSGKKWGCNG VGDDMFSFGF DGQYIYAGIA
     ALKLSKLIGG IEKFVGTHEF RKGDVIGCSL DLAVPEIQFS LNGHQIGTSV RNFSSCDCLF
     YPVMSLSAIV SCRFCFGGSQ GKLRFGPKKG YLPISEAAIT PVKLISCISF GDNRKGYFAG
     PSTVISDYIV FQPKPIDTKD VSLPKHLEDV HEKLAENIHE LWAMDKIEKG WIYGERRSET
     QKTHPCLTSY ERLPTAERSY NLNLAKETLK TIVALGYRIE LGKASDRVKT CRLGQKYDNE
     YYDAKNLWSR CFSFLMSNGY KPAPLDTREY ELNETLETLV DQLAKNMHNI WAQSKIQRGW
     TYSNNEVRNV NIKTTSHLVA YDFLDPNIKA ANRDKAGQII KSLLVYNYCI EPPTAEQDEG
     AVKQAQVMNL QKRTYRFEKS YAVKSGKWYF EFEVRTSGFM NVGWMDVSAS PDNDFGLHKS
     SYAYDGYLGR KWHGESESYG KKWNVGDVVG CFLDLTDRTI CFSLNGELLL DSSGTEVAFD
     NVSAEDGFVP AFSLAPGQIG RLNCGQNVNT LKYYTTCGLQ EGYEPFCIRM SRQAPMWIAK
     CEAEFDEINE EEKRFKVTRI PQSGDNPPCL KLQCKSAGML ERCSLALFRL NLPVFCKEAN
     DSRACNQYFT ETLSERNAGK RNCETDRTAE SGRRGKMKGV RGSRNQDENI SFHDQQNYAE
     QYEVGNHAVM KGNYLVQKTF SLDEDSSEVI ENRFRKGPRL RSSASEVNLK EKESIDSQDK
     ISASYATAFG QRMRDVSVGR SRKQNARKLQ DGCASKSKIR SDENDKFSSS RLSSRKLDDR
     VADVDSTESL DMPKSGPGRR PTVIRLESDS KVKKRSNYFS SGHDLLVEAS KLSAPSGSQH
     VSTGASVSFY STPDDYYFGI RVFPGQDLAN IWIGWLTPQF SFIGSQIAAD SQRICFLEST
     HGTLDNIQEF RSCYIVNGLE LLTAAGGSSN VSKMAGLLAG CLINTATGEL KFHANGKQTE
     MSYRVEPGTI LYPAVFVLPT SREVLQFELG NIEKTLPIAS AQLNERSNAV QLMCPPRLKI
     EICKTRTWLR VPDQCARVTS LKLSDTRGWS VLCDDLVRTM MLYVPERDSS IDILELVEHE
     SLCTFHQQTL RLYCSLCAQG NFKIAHILCQ HVDEDQLMYA IQSKYLSGSL RHCFYDVLIA
     IHLKCHYDAR LAESHEYIIP LNAKLKDRNY FNYETKSVYP HALNSDITLK SSINVMEVKK
     KISAEDEKFL MSPTFDFHSL KQYVVDALEE ATLEALMNSR DLIGGTNTTH FVPILKLFDT
     LLIVGLLSDT DIHRFFRLLN PRSFQETLDS PQNVKGLVDL DLDEMVQLEL CHIMNHLCDL
     QLQGRVESLI NFAETFVGET QNDQLRRYLE IKQTDMPSAE AARKTKEFRC PPKEQMLKLL
     DFKADRDVQT DEEGELEVSA MSEFLQRVLR EFHCNMVKCI GNSDKNDDNY SENVEQKQLE
     CENMNWVEKL AWMVVPVPPA LLSEDERIKF DGEEAFRNII LSTLIKWTGN KAIDDPNLIR
     EIFGLLLRQY TRISEVKSAL KTAYCIHERS TEDVQSFLDN LCQIRRLLCV QFEATEEEVL
     KNSLWDMMNN RVFFQHPDLM RLLKVHENVM TIMVNVLSRA QKSELDDRRN RSTQDDIKKA
     FQSSISDLVV ACCKFLCFIC RSSTKNQAAM FDHLPFLLDN ATMLLAKPSL RGSVPLDVAY
     YSFMENSELA LALKEDDLEK VAFYLSRCGL QANAEMVSKG YPDIGWDPVE GERYVDFLRF
     CVWVNGECVE ENANLVIRLL IRRPECLGPA LKGQGEGLFR AFKDAISLSS EISNLHKGRD
     LRSRFNFDLS HYPNPEIEEE DYIDLGAAIL GFYSSLADLL GKCAPDHLTV KSGKGESVRL
     RSILRSLTSV EDLEAILALR FLLPNVFAAK EENVRSSCIG LLPCHKQSIL LFLERVYGLV
     DKEMVFRLLE QSFILDFRAA TILDHPAYAE SDLALALNRY LCGSVLPLLT SHAHCFADAE
     HYYSLLEATL HTVYRMSKIK SLTKSQRSAI TEFLLAFTKE IHPGMMKKLL QKVVVDISSL
     NEFATVPLQI MTQHYECFSK HYGISLHEDM ASEEQKRLSM LLFTTIFDSL GKRAFDSDLF
     ASALPCLTAI GSALSPDYAM QSYAEEDIQS MNVSSDHMEV WRPHPVDASN VQLSVNLQNL
     VQRFAQHFHD SWASRKLEKG WRNDDIYSRT NCTHPRLKPF GMLKEFEQNF YKERCSECLK
     ALLAWGYSID QETQVSGIQP KAMNPTSNVR SASVFCPQPI DLSNMTLSEE MCELAERMAE
     NSHLIWVSKT IEDLNDANTG IMVLLVPWDI LADSEKRKHR FRAQEVLKFL QYQGFRLKSP
     LQRNKEEYEQ TVVDSNAHRP VEKRFACNLL EKLLAYLENA AQKMDVIKPS KQFSRYRNYT
     LPSEDVKFFG KVLLPLLESY FRSHRNYFTA ASSASLSGVA SIKEKEMVAG LFHRLMSVFR
     TKHNAFGCHV KSTVRCLQVL LQAIDFRSLV KINSDTLRTC AQIFLTNMVS DLMNITKEIK
     NNGRYAEIKG KTLPCTSSLL FLYEAMLPLL TTLFCHLSKH GHGQDFLVND IQVGCYKIAD
     CLYMLAAPIT ITRKSVKEEM EKHRSSIGQC LSAFACCFPV AFLEADFNAN SRCSTVDRQH
     LLSESKDAST SLLVNIPSLG NLLSNIEQLS NTNGKYQDAP AIFDVDIPML CSYMSFWWQH
     GPTNNTQEKK LSAVSSDHIN RLFSSCSRLI CNHIGIAHAD WICHLAPFIT PMINYVTIEP
     VRDYLLPMAE KVRMQADLAF KEEEKHRMHP DVFDESAVIE LHSILIRDVY ALYPILIKFT
     DLHRARWLKN PCWETNALFE HVAFVFKLWT TSQHMKREEL NFVTQFESDF MTGTSRKTGK
     AAVAFRKKKR REGKRREKDS GSIVVACLKR LLPVGLSVFG GRELDLLQKV KEKYMKKEND
     ERIKEYIFSS LAVPDQENVF DKSHWQRKLY QQIGKAQMLG IDSMSQEMVV DKIIFMGVTL
     CNLHNNRLNI RKRFKQMLGA RLYRLKESVL LLHVFEWLHY TAFQSMLPIA YIEKWLKSEK
     VDEDLLISEV TVASEGRIQR LREDVEEVDE QCPPDPLSQL VQCFQRAATS ERKQLVPIVD
     DNLYIEYVRV MASSIHISED EENNAEDDAI SMEAQELEKQ QLLHEQSRLA DRGVAVMVLM
     YLSACNGEPN VMVEKTLALG IHILNGGNSE VQNIMLNYLQ EKKDVRFFSS ISGLMNRCSV
     LNLEIFERQL KAEGLGMGAE LSVGKHQNLN DSEFICSLFR FIQLTCEGHN SEFQNYLRNQ
     PGNTTSINLI ICTVDYLLRL QESIMDFYWH FSSKEVVDEA GKAHFLKALS VCSQVFNTLT
     ESIQGPCVGN QMALANSRLW DAINGFFFLF AHMMDKLSKN HTQLELLREF LSLQKDMIVL
     MLSMLEGNIL NGSIGKQMVD TLAESQQNVQ LILKFFDMFL KLKDLTTSQA FQEFDTNKDG
     WISPKEFLRA MEAQKMYSTE EINYLMMCTD VNNDGKIDYM EFTERFHNPA KDIG
//
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