ID A0A0V0YIJ9_TRIPS Unreviewed; 1120 AA.
AC A0A0V0YIJ9;
DT 16-MAR-2016, integrated into UniProtKB/TrEMBL.
DT 16-MAR-2016, sequence version 1.
DT 13-SEP-2023, entry version 19.
DE SubName: Full=Solute carrier family 12 member 2 {ECO:0000313|EMBL:KRY00162.1};
GN Name=SLC12A2 {ECO:0000313|EMBL:KRY00162.1};
GN ORFNames=T4E_5679 {ECO:0000313|EMBL:KRY00162.1};
OS Trichinella pseudospiralis (Parasitic roundworm).
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Enoplea; Dorylaimia;
OC Trichinellida; Trichinellidae; Trichinella.
OX NCBI_TaxID=6337 {ECO:0000313|EMBL:KRY00162.1, ECO:0000313|Proteomes:UP000054815};
RN [1] {ECO:0000313|EMBL:KRY00162.1, ECO:0000313|Proteomes:UP000054815}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ISS141 {ECO:0000313|EMBL:KRY00162.1};
RA Korhonen P.K., Edoardo P., Giuseppe L.R., Gasser R.B.;
RT "Evolution of Trichinella species and genotypes.";
RL Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KRY00162.1}.
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DR EMBL; JYDU01000010; KRY00162.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0V0YIJ9; -.
DR STRING; 6337.A0A0V0YIJ9; -.
DR Proteomes; UP000054815; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015377; F:chloride:monoatomic cation symporter activity; IEA:InterPro.
DR Gene3D; 1.20.1740.10; Amino acid/polyamine transporter I; 1.
DR InterPro; IPR004841; AA-permease/SLC12A_dom.
DR InterPro; IPR018491; SLC12_C.
DR InterPro; IPR004842; SLC12A_fam.
DR NCBIfam; TIGR00930; 2a30; 1.
DR PANTHER; PTHR11827:SF103; SODIUM CHLORIDE COTRANSPORTER 69, ISOFORM E; 1.
DR PANTHER; PTHR11827; SOLUTE CARRIER FAMILY 12, CATION COTRANSPORTERS; 1.
DR Pfam; PF00324; AA_permease; 1.
DR Pfam; PF03522; SLC12; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000054815};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 123..144
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 156..181
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 202..226
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 250..269
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 276..296
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 326..348
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 360..380
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 424..447
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 480..497
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 503..524
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 559..576
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 128..618
FT /note="Amino acid permease/ SLC12A"
FT /evidence="ECO:0000259|Pfam:PF00324"
FT DOMAIN 627..1118
FT /note="SLC12A transporter C-terminal"
FT /evidence="ECO:0000259|Pfam:PF03522"
FT REGION 1..63
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 974..1036
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 1..55
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1120 AA; 124678 MW; 0AFAEE098DAE786E CRC64;
MQNESDKENT ASAMVSKEAE LQASSETKLT PGELQKSSGT NSDSENEQIP ANNRNLPATE
PMPHLQNYAD KDVHHFTNSN LKKRPSLSQL HSDSVIHLDN IIDHKQEVPH LDGKQTKKAQ
QKLGWIEGVL IRSSLSVFGV IFYLRLTWIG AQAGIALGSI IIVLSSLIGL LTALSLSALC
TNGRVQSGGV YYIVSRTLGP EFGGSIGIIF CLANVTATAI TITGFAETVV SLMGRFHTQL
VDGEIMDIRI IGWITGCVLL MIVFTGVNFE AKAQIVLMVV LVASVLNYYI GTFIPVSEEQ
MARGVTGYDR NTLKSNFFPD WRGEDFFSIL AIYFPAVAGF MAGANISGDL KHPESAIPKG
TLWSMLITGG IYLSVVWVTG STVLRDASGS IEDLRDGTLT DCAANFTCQY GTQNSYEVLE
LEGAWGPLVT AGIFAASLSS ALGAMISGPK LFQAVAKDKL FPKIEFFAEG HGRNKEPRRA
IVLLFVISMA VIGIGRINVI APIISNFFMA TYALINYACF DASFAKAPGF RPSFTFYNKW
MSLIGALICF GFMFLINWWA ALITTAFAIM LYVYLLRRKP DVNWGSSLEA NSYLSALRRM
LKLQFTRDHI KTYRPQILLL CGSPVRRPEL IDFVSNITKN SSLLICGHVI LGSPSEKVLE
VVDRYNKHMI VWLKSRRIYG FYSPVIAPNL SEGAHYLLQT AGMSYLKPNI LFLGYKNNWI
ESNAKEISEY FQLIHYAFDY DKALIILRLP KGFDISSLLN QETVNDSISD NVTVQGAHNV
RCKYIRSDGS SIIVSPLRMT ASMDSVFTDT VSINFGAYDN PRFHDSRLDI NSEKGIIDGN
PSFDLNDSEY IMHDRPYNSM RTNINDSEVD SSIDAASIRD LNFEILTSNT HEALKGRKKS
TIISKVMKGD KWKKTLAGGQ QLNVFKNRIK KAVIDVWWLC DDGGLTILIP HLLTLERSYL
EEAKLRVFTV ATDAEKFEEQ KKELSNLLDS FRIDVKDVTV IPDISQQPKE STINEFNQLI
SKFKAADRNS NQLEEELLAV ATDNAELSML KYKTYQTLRI REELLENSKN ANLVVITLPV
PRRNGVSAAL YLSWLEMLSR DLPPTLLIRG NQKAVLTCEN
//
