ID   A0A0V0ZDT2_9BILA        Unreviewed;       931 AA.
AC   A0A0V0ZDT2;
DT   16-MAR-2016, integrated into UniProtKB/TrEMBL.
DT   16-MAR-2016, sequence version 1.
DT   27-MAR-2024, entry version 24.
DE   SubName: Full=5'-3' exoribonuclease 2 {ECO:0000313|EMBL:KRY10706.1};
DE   Flags: Fragment;
GN   Name=XRN2 {ECO:0000313|EMBL:KRY10706.1};
GN   ORFNames=T12_4193 {ECO:0000313|EMBL:KRY10706.1};
OS   Trichinella patagoniensis.
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Enoplea; Dorylaimia;
OC   Trichinellida; Trichinellidae; Trichinella.
OX   NCBI_TaxID=990121 {ECO:0000313|EMBL:KRY10706.1, ECO:0000313|Proteomes:UP000054783};
RN   [1] {ECO:0000313|EMBL:KRY10706.1, ECO:0000313|Proteomes:UP000054783}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ISS2496 {ECO:0000313|EMBL:KRY10706.1};
RA   Korhonen P.K., Edoardo P., Giuseppe L.R., Gasser R.B.;
RT   "Evolution of Trichinella species and genotypes.";
RL   Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the 5'-3' exonuclease family. XRN2/RAT1
CC       subfamily. {ECO:0000256|ARBA:ARBA00006994}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KRY10706.1}.
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DR   EMBL; JYDQ01000220; KRY10706.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A0V0ZDT2; -.
DR   Proteomes; UP000054783; Unassembled WGS sequence.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-KW.
DR   GO; GO:0004534; F:5'-3' RNA exonuclease activity; IEA:InterPro.
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   GO; GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.
DR   CDD; cd18673; PIN_XRN1-2-like; 1.
DR   Gene3D; 1.25.40.1050; -; 1.
DR   Gene3D; 3.40.50.12390; -; 2.
DR   InterPro; IPR027073; 5_3_exoribonuclease.
DR   InterPro; IPR041412; Xrn1_helical.
DR   InterPro; IPR004859; Xrn1_N.
DR   InterPro; IPR017151; Xrn2/3/4.
DR   PANTHER; PTHR12341:SF77; 5'-3' EXORIBONUCLEASE 2; 1.
DR   PANTHER; PTHR12341; 5'->3' EXORIBONUCLEASE; 1.
DR   Pfam; PF17846; XRN_M; 1.
DR   Pfam; PF03159; XRN_N; 1.
DR   PIRSF; PIRSF037239; Exonuclease_Xrn2; 2.
PE   3: Inferred from homology;
KW   Exonuclease {ECO:0000256|ARBA:ARBA00022839};
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW   mRNA processing {ECO:0000256|ARBA:ARBA00022664};
KW   Nuclease {ECO:0000256|ARBA:ARBA00022722};
KW   Reference proteome {ECO:0000313|Proteomes:UP000054783};
KW   Transcription {ECO:0000256|ARBA:ARBA00023163};
KW   Transcription regulation {ECO:0000256|ARBA:ARBA00023015};
KW   Zinc {ECO:0000256|ARBA:ARBA00022833};
KW   Zinc-finger {ECO:0000256|ARBA:ARBA00022771}.
FT   DOMAIN          6..260
FT                   /note="Xrn1 N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF03159"
FT   DOMAIN          329..763
FT                   /note="Xrn1 helical"
FT                   /evidence="ECO:0000259|Pfam:PF17846"
FT   REGION          881..931
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        881..916
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   NON_TER         1
FT                   /evidence="ECO:0000313|EMBL:KRY10706.1"
SQ   SEQUENCE   931 AA;  107301 MW;  D66A52AEFD118759 CRC64;
     LLSTKMGVPA FFRWLSRKYP SIVMNCIEDT PRDVDGTTVP VDNTQPNPHG IEFDTFYLDM
     NGIIHPCCHP EDKPAPKSEE EMMVAIFEYI DRLMCIVRPR RLLYMAIDGV APRAKMNQQR
     TRRFRASKEA AEKEEQIRQI REDLRAQGIP LPAESTDKQH FDSNCITPGT PFMARLAICL
     RYYIHERLNT DPAWQNLLVI LSDASVPGEG EHKIMDYIRH QRACASHDPN THHVLCGADA
     DLIMLGLATH EPNFTIIREE FVPNLPRPCE ICNNYGHTMQ DCQGLSILEN ENEEAHRPVL
     KKTQFIFIRL SVLREYLQRE LEMPNIKFKY DFERCVDDWV FMCFFVGNDF LPHLPSLEIR
     EGAIDRLVKL YKDCVYRTGG YLTENGFVNL KRVQLIMSEL GKIQFSNKAK MRRMQAESFD
     APAFIPQNAF APTPIGESPL PLSNAKRTAM EMRQVAMAVT SSTKREFNGA ANAEDANDEG
     PLDEVRLWEC GWKDRYYLVK FQCSPKDLKF RHHVANCYVE GLCWVLRYYY QGCCSWKWYF
     PFHYSPFASD FMNIGDLKID FSEKTMPIKP LEQLMSVFPA ASSKHLPKSW AALMHDPKST
     IIDMYPSDFK VDLNGKRYAW QGVVLLPFVD AERLNEALEV VYPDLTEEER FRNRQGNDLL
     FISSKHEAFD FIQSIYEGDM SAEWLNMDPS LCNGISLMVK PYKFYVPVGK TVHSPLPQCS
     DVENNHVLSV FCLNPQFPDD YIFSTARLSG AVDPQPVLKP KDWDDDRDGR YRPVTGFVQS
     PVTAQLNRAS KRILDFEMRS VQSYNARMPN QYYSGIDNRQ YYNSTSPDYV RYGGNRGNYG
     QCRGSFSGRG GTVGRDLAPQ YQRGGWSGAK DKICQAESPY RTVRHSTPST FEAHSGRGRA
     QSWQSHYNSS SYRPRIPSRN PRYRTEHFKP Y
//