ID A0A0V0ZE75_9BILA Unreviewed; 1959 AA.
AC A0A0V0ZE75;
DT 16-MAR-2016, integrated into UniProtKB/TrEMBL.
DT 16-MAR-2016, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE SubName: Full=Pappalysin-1 {ECO:0000313|EMBL:KRY10785.1};
GN Name=Pappa {ECO:0000313|EMBL:KRY10785.1};
GN ORFNames=T12_8919 {ECO:0000313|EMBL:KRY10785.1};
OS Trichinella patagoniensis.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Enoplea; Dorylaimia;
OC Trichinellida; Trichinellidae; Trichinella.
OX NCBI_TaxID=990121 {ECO:0000313|EMBL:KRY10785.1, ECO:0000313|Proteomes:UP000054783};
RN [1] {ECO:0000313|EMBL:KRY10785.1, ECO:0000313|Proteomes:UP000054783}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ISS2496 {ECO:0000313|EMBL:KRY10785.1};
RA Korhonen P.K., Edoardo P., Giuseppe L.R., Gasser R.B.;
RT "Evolution of Trichinella species and genotypes.";
RL Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00302}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KRY10785.1}.
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DR EMBL; JYDQ01000218; KRY10785.1; -; Genomic_DNA.
DR Proteomes; UP000054783; Unassembled WGS sequence.
DR GO; GO:0008237; F:metallopeptidase activity; IEA:InterPro.
DR CDD; cd00033; CCP; 2.
DR Gene3D; 2.60.120.200; -; 1.
DR Gene3D; 3.40.390.10; Collagenase (Catalytic Domain); 1.
DR Gene3D; 2.10.70.10; Complement Module, domain 1; 3.
DR InterPro; IPR013320; ConA-like_dom_sf.
DR InterPro; IPR006558; LamG-like.
DR InterPro; IPR024079; MetalloPept_cat_dom_sf.
DR InterPro; IPR000800; Notch_dom.
DR InterPro; IPR043543; PAPPA/PAPPA2.
DR InterPro; IPR035976; Sushi/SCR/CCP_sf.
DR InterPro; IPR000436; Sushi_SCR_CCP_dom.
DR PANTHER; PTHR46130; LAMGL DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR46130:SF3; SUSHI DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF13385; Laminin_G_3; 1.
DR Pfam; PF00066; Notch; 1.
DR Pfam; PF00084; Sushi; 1.
DR SMART; SM00032; CCP; 5.
DR SMART; SM00560; LamGL; 1.
DR SMART; SM00004; NL; 3.
DR SUPFAM; SSF57535; Complement control module/SCR domain; 4.
DR SUPFAM; SSF49899; Concanavalin A-like lectins/glucanases; 1.
DR SUPFAM; SSF55486; Metalloproteases ('zincins'), catalytic domain; 1.
DR PROSITE; PS50923; SUSHI; 1.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Reference proteome {ECO:0000313|Proteomes:UP000054783};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Signal {ECO:0000256|ARBA:ARBA00022729};
KW Sushi {ECO:0000256|PROSITE-ProRule:PRU00302}.
FT DOMAIN 1444..1502
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT REGION 1797..1816
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1959 AA; 218991 MW; 8701701799564EA5 CRC64;
MEVWLLIKLD FIQSQERENW CFFSNVGQRE IGKEKDVVGE LRIRHNFSTA LTGMTAAAAV
ESDVSNLNTS NGPLDSGWVW GMRRRLYIKG SNLSSRFDSR NYKKQSRRRV CRFLVFSSSA
LASSASNCSY SYSSFAAAAA TTTTTTTTTT TTTTTTTTTT TTTTTTTTAT TYSSFAYSSF
VFCVFAMHHL LLLFTLCLAC LTSAVDDTTL ANCAVGTGTR LDHRYHPNVR HPRSVSNGGG
YSTTAKAIYF DGQERTVRLQ DVGQLPRDQF TLTVWIRPEG GQGDPAIIAE LADGCSGDDD
DDDGPPFVWQ LGIATKTASR EKGAHFFFQM RNEMSSSATV LWSHYPYKAE RWVHLAVTYD
GIMLRFFVGG ALVATTDKQI GPLFSNIKSA CKHLLLGGPM PGRFDEGHTM NFRGAVDELQ
LWSTFQEYDF IQKMATGRNA QEAANNNNNN HNAQHPTTTS VLIINAQSVA KWKPAGDFAP
KFVPSDLDAF FNTYQLLVHA CGQTVCDHPD VVRSYSANWE LRQSKVVRYK VADDVINIVD
NSTGKGIVSD RKIELQHGSL SGAFAKYNIT WQMEIVKIAN ANLRKKKIIF GCDSSKIGNK
QCDLECRHPI TGNDGGDCDE LMLVRCQRRM LGNGRCDPEC NFPEYSWDQG ECCNKTLTDV
TTNCIDPQSP FRPYIGIEEY KRMLNVSNED ALTISFVEWS NGDLIGLSTF PWEKHVFSIY
GGIVVQPKRF GSDGHRNNLI HEFGHALGLW HVHHGISEMT CDDPCRETKP SLYTGDLCED
TNPTPKNVEC KDPEYVSFDS RQSMAELSGC ESGSQMYLNT PYDNYMSYSD GECATHFTPQ
QVARMHCYLD LKYSSWMASS ESLREYVPTA PRILRKTETS LTFAWLPPLS WHQCKPAVER
CQHCECDTDG RFIQYASRVI ANHTARTTSY WSPDQALGPP DAEPCEASTK SWLPDAQNCD
NNNACSLVLG FEVAVVPAHL KLWISWNAAD GLKHFILHFD DSSMIALPPA TAFCDMPYTL
SLDTDKRLTK VELTTSSPFV SIDAVQIVSN PNHELCSKCS HIDYNIVREP PFPKPPLVQS
TADTFFTDRD LKQDQVYMYR IGARRTNSNG AVYFSPPLIY SHSWSFCGDG NLDEIAYVFV
LARLCSLVWR SPSFCYSLDG VQHAHAINGS PIMMSDMPDV SYAPEHSDQW AARAFSNAEP
INLRCNTTMI LGPPRNLVCQ VNSPPGLSWQ PCLPSVMKNV WIEVEFEQPV VATAVFVHLA
SDGYAGVDSE YRFLRLELVS VDNKYYELQN SKLVTVSCAK SPLEYPVWHD LTKPFFYSRA
VRIHLSSDRI SIAAVRLRSK RNFDPVVLEL CSKSDMLYSV FANQCVSSQC SVVSCKSVIV
NHADVQCTGH SNGDSCIVTC MKGYHLVKHE RAQTHAFSYS SQRSAKIICL NGQWSVGNLK
CEPVDCGWPK IFRAEVLCPD GTRLGAKCSF RCLRPAIMQG TKREITCGER GAWSVPEAYC
QLSCGPSLEG ELNGRAVSKL CRINFLTLDL KSVGYPVGTK CRIVCKAGYH VEGHSINKRV
FKRVCDRNGH WKGHRCVKIK CPEPAIVYRG LYNCTKGFEV GSQCSFYCPF SSQIRDSVCM
MDGTWSIADP CVLPKDVTCS IPHAPGHIVV SCPSKRLVGS TCHVACDAQG YDPVVEHVVN
SDRNFKMHVL QKITKLTCSI KRKWEPEVES LICVKRCTQD FVGDGWCDFQ NNRAYCGWDG
GDCCASTAKG GKVKLMFPLL CTSHLCRCLD PYAVENRNPR IIPRAFLVQG YHGGEALDKE
EEEEEDLDEN NSTEHIQSPD LMMLMNNDKN RTNPSWKLLG LGSRVKFAWE TSGGGFSTAK
LDHLSSSMLV LFLQALKNVS SDPRDPFLLL QNSATTNATI KRLKELDAMT RFLKRPTAST
AQPLTWTTRW FRRRVVHPQL STSILKALRK QHESLQVKS
//
