ID A0A0V0ZHA3_9BILA Unreviewed; 2451 AA.
AC A0A0V0ZHA3;
DT 16-MAR-2016, integrated into UniProtKB/TrEMBL.
DT 16-MAR-2016, sequence version 1.
DT 24-JAN-2024, entry version 23.
DE SubName: Full=Proteasome activator complex subunit 4 {ECO:0000313|EMBL:KRY11771.1};
DE Flags: Fragment;
GN Name=psme4b {ECO:0000313|EMBL:KRY11771.1};
GN ORFNames=T12_13498 {ECO:0000313|EMBL:KRY11771.1};
OS Trichinella patagoniensis.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Enoplea; Dorylaimia;
OC Trichinellida; Trichinellidae; Trichinella.
OX NCBI_TaxID=990121 {ECO:0000313|EMBL:KRY11771.1, ECO:0000313|Proteomes:UP000054783};
RN [1] {ECO:0000313|EMBL:KRY11771.1, ECO:0000313|Proteomes:UP000054783}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ISS2496 {ECO:0000313|EMBL:KRY11771.1};
RA Korhonen P.K., Edoardo P., Giuseppe L.R., Gasser R.B.;
RT "Evolution of Trichinella species and genotypes.";
RL Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the BLM10 family.
CC {ECO:0000256|ARBA:ARBA00005739}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KRY11771.1}.
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DR EMBL; JYDQ01000183; KRY11771.1; -; Genomic_DNA.
DR STRING; 990121.A0A0V0ZHA3; -.
DR Proteomes; UP000054783; Unassembled WGS sequence.
DR GO; GO:0000502; C:proteasome complex; IEA:UniProtKB-KW.
DR GO; GO:0070577; F:lysine-acetylated histone binding; IEA:InterPro.
DR GO; GO:0016504; F:peptidase activator activity; IEA:InterPro.
DR GO; GO:0070628; F:proteasome binding; IEA:InterPro.
DR GO; GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
DR Gene3D; 3.40.50.1010; 5'-nuclease; 1.
DR Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 1.
DR InterPro; IPR011989; ARM-like.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR039436; Asteroid_dom.
DR InterPro; IPR032430; Blm10_mid.
DR InterPro; IPR021133; HEAT_type_2.
DR InterPro; IPR029060; PIN-like_dom_sf.
DR InterPro; IPR035309; PSME4.
DR InterPro; IPR021843; PSME4_C.
DR PANTHER; PTHR32170; PROTEASOME ACTIVATOR COMPLEX SUBUNIT 4; 1.
DR PANTHER; PTHR32170:SF3; PROTEASOME ACTIVATOR COMPLEX SUBUNIT 4; 1.
DR Pfam; PF16507; BLM10_mid; 1.
DR Pfam; PF11919; DUF3437; 1.
DR Pfam; PF12813; XPG_I_2; 1.
DR SUPFAM; SSF48371; ARM repeat; 2.
DR SUPFAM; SSF88723; PIN domain-like; 1.
DR PROSITE; PS50077; HEAT_REPEAT; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW DNA damage {ECO:0000256|ARBA:ARBA00022763};
KW DNA repair {ECO:0000256|ARBA:ARBA00023204};
KW Proteasome {ECO:0000313|EMBL:KRY11771.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000054783};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT DOMAIN 325..816
FT /note="Proteasome activator Blm10 mid region"
FT /evidence="ECO:0000259|Pfam:PF16507"
FT REPEAT 1695..1721
FT /note="HEAT"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00103"
FT DOMAIN 1749..1831
FT /note="Proteasome activator complex subunit 4 C-terminal"
FT /evidence="ECO:0000259|Pfam:PF11919"
FT DOMAIN 1931..1993
FT /note="Asteroid"
FT /evidence="ECO:0000259|Pfam:PF12813"
FT REGION 2398..2433
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 719..746
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 2415..2431
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:KRY11771.1"
SQ SEQUENCE 2451 AA; 281776 MW; FA016BDFF566027E CRC64;
LLCAMSKVNE VDVVKMNRQP LHERFILKYL PYYDKLKEEV TEHIVKIKSG LASSLLLREC
RPGLQFWISQ IESMINVYGY CFTKEDHIMF VKIIYELLAS PDIDYPTAEY LCTALVALLK
KWYYISPKDL QLNWKVLFAL YERVIALDLD DGFQEVVPKG LPVVLTNAVK LSSMYFSKEA
TQEILNRLRP SIGFLTGQIK MNIFITLCNF LPAAMSPNER ECGYELWFDE LMYWWQNMPN
SGMWEYYFVE LLQRLAKNNV GCIDWNPHMN FIFNKILRQF RLSVKDTRDS SNFNLGGTVK
SYDLKIMGSL VCYMATPKND VLKYLDRLFK AVQSYCHPSN SGKWQNAIFS FIEALCLNIC
ERLNRERCPR KGWLATIPDD CQLDDQYVSK LVSSILPCVQ AGMFGKGSSA IVASCFHYLS
RMDPAAVVPI VLDSCESSLL SITEPHRMQQ SLASMISVGL PLLRLARHDA NGLRLIPFLK
SLQSTIDVFD FSKISTILET LSYFFQLLPL VDNCDTPLFV DNLNDIEKEL CAGTALFEDI
VDGFVDWLLY ALTSYGNNVS NGNSNAPDDC PEANVYKEAV SAVGRFLLAN SSDMVVKNAM
ENILRFAEEN EFESGMAMVY IAELCCYACE ANFDYCFKRI WNLYFGRLKS MITEETKNEE
EVHFLIINNI MALDQFLRFQ GKSIVEFVDD MLELFDLLLP LQAPTAVNCY SVIVETVLMQ
LTEVKLDDAE RNKEALNQSV DRFIAIRNWG EQFDSKNFQM TWKFPGQAEV DAVSRIFEKI
LYPQLRLLEQ PEKLTKNQIV KCLNLTRHCI SGASVVLPFM DGKLIDVTSS KVPRDVIANH
SVYDCYPSII IGGPLDCDGK NIRNMVKDTV NNLLDYMLAN REHETAVLEE ICWIYQDLLM
SRGCSMKQTF ATDVDSDDDD DDDENCSVLE EELTNLHKKM SDEVKGRNGM TKILFAFKVK
LFHQKRLVCD CEMVHNESHT EVFSKLFKLL TSPYNEIREY ARGVFNNCFE TFPFSSKFVF
DMLLDTIAKY NNDSNDIASR ARFKGAMRML HDCNEIIRFC DSIWQATYKL WMSLARCPFP
REPLEIAMFM KMGKQIQSCF QMPEEVVKMG HLLCENFYMP SYITEADIEE AVVQERQRNE
NNEQTYKQLI CELVDIVEEQ KLPWSQECIV LKFLILQLHK EVAYPYRAVQ LFFKQLRSDH
IQIRRMAIKF FSRYLVLQKP KVRKVPLKIP NESPLYADQV KWPHKWGIRA DNAFCIYDKN
KLPKTAQEWN EATFAEKLHC GFYCWSRECT ADAPLSAQPA VDRPLCEMND SEVGLYTAFT
DAEFVEKFSM SLALDSKDIK PVDMCNCKFF RGLFFTFGES ILTTLKPILE KLVESERPEK
QRLAAEISSG LLYGMRLWPY EMQQRCLEWF SPMLEGIFDS FAPETMNNWL ISISEGLVFY
TVEQMSWFVE IVVRVIKRAI GTASQRSNYL YVLGLLLFTR NWQMVNVWNE LLPVVESKMA
DPSPSVQEAY GRMLRMMFHS DLADITNEMD IVIPSADLFI GRCLASLENL ILETEMSAPD
ELVEENLPEA ELERREKRSE SIWKLQTLLN FAFPLGSHVE NMPVRKCVLK LLPLLCYFEN
ESSGVDLKEL CQMKLKFCLS RIMMTENEAA CFLEQCEIVT KRKWWKARIS MLHVLQFCAF
SNLFSFNTDT NRDRLVEIIF SLLRDDQLEV RKAASNSLSS LLHCSFIQPT GELTACFTDW
CQSAEAEVRH AGILGLSAIV SSQPYAVPNY LPDILMQLCR YVNDSAHIVR TSVKETLSEF
KRTHVDSWRE HQLQFTDEQL SVLTGLFLSP NGLAFAHQIF LHFGIDSACG GDYVAFEKSC
RICLCVLKQS DISPVFFMDG KIDEVRYKRR TTILRQQSRM NLARQMSEQP CSKLLLPPLA
CDLLHRILTE HNITVYYCAG EADAFIAAYA NHHNYPVLSS DSDFFIFPLR AGYIPLPSVE
WESCNGVLKC SLYQFAHCEA HFPNLKPEVM PLFAVLSGND FVRGDLFRSF YNQISKPVVM
NGKDVCKTRQ HRNMNGLLNW LRGKSFAQAV EGVLSYVKKS SVRSLRQIIL SGAKFYQNTT
LMGNCEDPTR LTRRQLKNLP DWLVELYCAG QMPCPIVIAI RCNQTLILPT FVEDFTKPTI
YDSSTRLREA LYGIILKDTG KLQVKEYVRL NQAFRFRVIS VSSDWCSLSD IGNMTSSELR
AQFLRIVDCD EAEIISLSEK LQLYFLSLRY WSLSAAEFAS KNILIAFIAV AYCLFSVSAT
GQGFPKPFRL LNAIPVLDTR MKSKLYLQIT HSVNIWQASL TAMTWLNYVL KEPFKWPKIS
TLFSGRMLIN LACELSRDVK PMNLLEKKYF ASAANSFASF LEFCKPFQNI IDQAPLSATA
KPRKRRRPKQ KSSTKSAEKS PVTGQSTSSE WADVDEENRF SKLLNNNLKI S
//
