ID A0A0V0ZJG0_9BILA Unreviewed; 778 AA.
AC A0A0V0ZJG0;
DT 16-MAR-2016, integrated into UniProtKB/TrEMBL.
DT 16-MAR-2016, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE SubName: Full=Carnitine O-palmitoyltransferase 1, liver isoform {ECO:0000313|EMBL:KRY12491.1};
DE Flags: Fragment;
GN Name=CPT1A {ECO:0000313|EMBL:KRY12491.1};
GN ORFNames=T12_7874 {ECO:0000313|EMBL:KRY12491.1};
OS Trichinella patagoniensis.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Enoplea; Dorylaimia;
OC Trichinellida; Trichinellidae; Trichinella.
OX NCBI_TaxID=990121 {ECO:0000313|EMBL:KRY12491.1, ECO:0000313|Proteomes:UP000054783};
RN [1] {ECO:0000313|EMBL:KRY12491.1, ECO:0000313|Proteomes:UP000054783}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ISS2496 {ECO:0000313|EMBL:KRY12491.1};
RA Korhonen P.K., Edoardo P., Giuseppe L.R., Gasser R.B.;
RT "Evolution of Trichinella species and genotypes.";
RL Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the carnitine/choline acetyltransferase family.
CC {ECO:0000256|ARBA:ARBA00005232}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KRY12491.1}.
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DR EMBL; JYDQ01000163; KRY12491.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0V0ZJG0; -.
DR STRING; 990121.A0A0V0ZJG0; -.
DR UniPathway; UPA00659; -.
DR Proteomes; UP000054783; Unassembled WGS sequence.
DR GO; GO:0005741; C:mitochondrial outer membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0004095; F:carnitine O-palmitoyltransferase activity; IEA:UniProtKB-EC.
DR GO; GO:0006635; P:fatty acid beta-oxidation; IEA:UniProtKB-UniPathway.
DR Gene3D; 6.10.250.1760; -; 1.
DR Gene3D; 3.30.559.10; Chloramphenicol acetyltransferase-like domain; 1.
DR Gene3D; 3.30.559.70; Choline/Carnitine o-acyltransferase, domain 2; 1.
DR InterPro; IPR000542; Carn_acyl_trans.
DR InterPro; IPR023213; CAT-like_dom_sf.
DR InterPro; IPR039551; Cho/carn_acyl_trans.
DR InterPro; IPR042231; Cho/carn_acyl_trans_2.
DR InterPro; IPR032476; CPT_N.
DR PANTHER; PTHR22589; CARNITINE O-ACYLTRANSFERASE; 1.
DR PANTHER; PTHR22589:SF31; CARNITINE O-PALMITOYLTRANSFERASE; 1.
DR Pfam; PF00755; Carn_acyltransf; 1.
DR Pfam; PF16484; CPT_N; 1.
DR SUPFAM; SSF52777; CoA-dependent acyltransferases; 2.
PE 3: Inferred from homology;
KW Acyltransferase {ECO:0000256|ARBA:ARBA00023315};
KW Fatty acid metabolism {ECO:0000256|ARBA:ARBA00022832};
KW Lipid metabolism {ECO:0000256|ARBA:ARBA00023098};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000054783};
KW Signal {ECO:0000256|SAM:SignalP};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000313|EMBL:KRY12491.1};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..16
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 17..778
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5006873887"
FT TRANSMEM 76..98
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 105..128
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 15..61
FT /note="Carnitine O-palmitoyltransferase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF16484"
FT DOMAIN 184..765
FT /note="Choline/carnitine acyltransferase"
FT /evidence="ECO:0000259|Pfam:PF00755"
FT ACT_SITE 480
FT /note="Proton acceptor"
FT /evidence="ECO:0000256|PIRSR:PIRSR600542-1"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:KRY12491.1"
SQ SEQUENCE 778 AA; 89848 MW; 6F0A0D7DF3B062D4 CRC64;
LLTVLRILFV LSKTMAEAHS AVAFGFTVSH DGVSLNYDKE LLKIVYQSIS RSYKRRVARF
KNNLRAGIYP ASPSSYVFIV AVMVAVSLAN IDLSFGLIDW AQKRFFGISF TSLLFCSVVY
SSLCWLAIVQ IARLTIKLMF MYRGWMYERL RNTRMATKFY LLIVKLILKH EPMLKSFQGA
LPRLPLPTLR DTLRRHLDTL KPLLNDESRQ RMERLSNEFE NTIGPKLQRY LTLKSWLSGN
YVSDWWEEYV YLRGRSALMI NSNFYGLDSL GHAGTTIQAA RAANITYASL LFRRLIERQE
LKPILIGVVP LCSSQYERTF NTCRIPGVEI DTLKHWNDAR HIAVYCHGAW FKVLIHDGRR
LLKPCELQII FSEILNNCYD VTDDERHLGA LTAIDRTSWA EIRQKYFSVG VNRSSLHAIE
SSAFTLCFDE EEYFYDPNDT SKLDHWAHMN LHGKGYDRWF DKSFNLIVSK NGKVGINAEH
SWYEFLADAP IMSHYFEYAT VFDILKLGYT AEGNCIGDVD ITPVPARRLK WDFTPELSRE
IAESVQKAEV LINDVEMALI VFREFGKGFI KKCQISPDGF IQMILQLTYF RDQRKFCLTY
EASMTRLYRE GRTETVRPVT FESCAFVRAM CDDTCSIEQR RDLLYKACEK HQKAYLDAMC
GKGVDRHLFC LYIVSRYLQL DSPFLKEVLS EPWRLSTSQT PQQQTDLVDT RKYPDYVSAG
GGFGPVADDG YGISYIIGGE NIISFHISSK RYCETTSSTR FRETLLQSLR DVRSLFDD
//
