ID A0A0V0ZVI3_9BILA Unreviewed; 842 AA.
AC A0A0V0ZVI3;
DT 16-MAR-2016, integrated into UniProtKB/TrEMBL.
DT 16-MAR-2016, sequence version 1.
DT 27-MAR-2024, entry version 31.
DE RecName: Full=Carnosine N-methyltransferase {ECO:0000256|ARBA:ARBA00015448};
DE EC=2.1.1.22 {ECO:0000256|ARBA:ARBA00012003};
DE AltName: Full=Adaptor protein complex AP-2 subunit sigma {ECO:0000256|ARBA:ARBA00031115};
DE AltName: Full=Adaptor-related protein complex 2 subunit sigma {ECO:0000256|ARBA:ARBA00029632};
DE AltName: Full=Clathrin coat assembly protein AP17 {ECO:0000256|ARBA:ARBA00032679};
DE AltName: Full=Clathrin coat-associated protein AP17 {ECO:0000256|ARBA:ARBA00032557};
DE AltName: Full=Plasma membrane adaptor AP-2 17 kDa protein {ECO:0000256|ARBA:ARBA00033221};
GN Name=Nudt13 {ECO:0000313|EMBL:KRY16726.1};
GN ORFNames=T12_12955 {ECO:0000313|EMBL:KRY16726.1};
OS Trichinella patagoniensis.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Enoplea; Dorylaimia;
OC Trichinellida; Trichinellidae; Trichinella.
OX NCBI_TaxID=990121 {ECO:0000313|EMBL:KRY16726.1, ECO:0000313|Proteomes:UP000054783};
RN [1] {ECO:0000313|EMBL:KRY16726.1, ECO:0000313|Proteomes:UP000054783}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ISS2496 {ECO:0000313|EMBL:KRY16726.1};
RA Korhonen P.K., Edoardo P., Giuseppe L.R., Gasser R.B.;
RT "Evolution of Trichinella species and genotypes.";
RL Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the carnosine N-methyltransferase family.
CC {ECO:0000256|ARBA:ARBA00010086}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KRY16726.1}.
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DR EMBL; JYDQ01000073; KRY16726.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0V0ZVI3; -.
DR Proteomes; UP000054783; Unassembled WGS sequence.
DR GO; GO:0030122; C:AP-2 adaptor complex; IEA:InterPro.
DR GO; GO:0030735; F:carnosine N-methyltransferase activity; IEA:UniProtKB-EC.
DR GO; GO:0035615; F:clathrin adaptor activity; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0072583; P:clathrin-dependent endocytosis; IEA:InterPro.
DR GO; GO:0006886; P:intracellular protein transport; IEA:InterPro.
DR GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR CDD; cd14833; AP2_sigma; 1.
DR Gene3D; 3.30.450.60; -; 1.
DR Gene3D; 3.90.79.20; -; 1.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR InterPro; IPR022775; AP_mu_sigma_su.
DR InterPro; IPR027156; APS2.
DR InterPro; IPR012901; CARME.
DR InterPro; IPR000804; Clathrin_sm-chain_CS.
DR InterPro; IPR011012; Longin-like_dom_sf.
DR InterPro; IPR015797; NUDIX_hydrolase-like_dom_sf.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR InterPro; IPR001841; Znf_RING.
DR InterPro; IPR017907; Znf_RING_CS.
DR PANTHER; PTHR12303:SF6; CARNOSINE N-METHYLTRANSFERASE; 1.
DR PANTHER; PTHR12303; UNCHARACTERIZED; 1.
DR Pfam; PF07942; CARME; 1.
DR Pfam; PF01217; Clat_adaptor_s; 1.
DR SMART; SM01296; N2227; 1.
DR SUPFAM; SSF55811; Nudix; 1.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
DR SUPFAM; SSF64356; SNARE-like; 1.
DR PROSITE; PS00989; CLAT_ADAPTOR_S; 1.
DR PROSITE; PS00518; ZF_RING_1; 1.
DR PROSITE; PS50089; ZF_RING_2; 1.
PE 3: Inferred from homology;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Methyltransferase {ECO:0000256|ARBA:ARBA00022603};
KW Protein transport {ECO:0000256|ARBA:ARBA00022927};
KW Reference proteome {ECO:0000313|Proteomes:UP000054783};
KW S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Transport {ECO:0000256|ARBA:ARBA00022927};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00175}.
FT DOMAIN 537..581
FT /note="RING-type"
FT /evidence="ECO:0000259|PROSITE:PS50089"
SQ SEQUENCE 842 AA; 97141 MW; 2B13B2306BDF85A4 CRC64;
MARMNSQRSS LSDYSFRTAK KCFEHYYSSS LTILQEKYSA YKALPEKHKA LIPTFFEHIA
RIRESITINM QFFTQIYTTG MHMVEEESRK NTLFAENVTR MTCEFVVGKT QQILHDVIRE
WSAVGISERK SVYGPILAYM EDLKKSTTPE SVKILIPNAG LGRLVLELAK LGYHCDACES
SAAHVLTANF MINHSDSNSP VTIYPWINKW TNHRNCAEQI QSVTVPDVRP DLIRNGKQCN
LVAGDFLNLY ADEHETYDII CTVRYINHPK KIRDYVEKVY DLLKPGAVWI NMGPMLYRGR
NEDSSVRVPP YELVRLHIQE LGFHFEKEQL GIPINITYYN QSMLSCTEKE ASAEFAEKSE
MIRFILIQNR AGKTRLAKWY MHFDDNEKQK LIEEVHAVVT VRDAKHTNFV EFRNFKIIYR
RYAGLYFCIC CDITDNNLYY LEAIHNFVEV LNEYFHNVCE LDLVFNFYKV YAVVDEMFLA
GEIRETSQTK MRDFIDLTHC DAEEKRRSKR GQKRKASADI SFVDLTDDKT EKSKLACCKC
EMSIQMLLKN GAVISSILCG HVFCNKCLLS IPTKRKSGCC PKLVLKTVIN QLLRKTTLLH
NSKRLTSYLV NKIRMHEWMK SNDSVLLAEF KRGNFAVCME KQPLIHSLNN NQTDQYKLLQ
INYECLKKVL PEYKLNFDVK DTALLDVVPM QSTTNDIEEE WTPVFALNIK NASSVGTRND
LAQALGGEFH DFRKVFLGTD TSNAKLLTKM RNIFRWHNSF QNCPRCTARL NFKVSKASAK
CPECDAVYYP PVAPVAITLV STADKKYLLL VRQKHHPKRL YTAISGFSEL VLATAVKKFS
SI
//
